Protective effects – Page 4 – Communicable Diseases Research

AI Aided Design of Epitope-Based Vaccine for the Induction of Cellular Immune Responses Against SARS-CoV-2

Genetics

Published on 2021-03-252022-10-31
Journal: Frontiers in Genetics
[Category] COVID-19,

[키워드] Coronaviridae Activation ADE administration adverse event Affect Against Analysis antibody Antibody-dependent enhancement applicability approach benefit bioinformatics carried CD8+ cellular immunity conserved Coronaviridae coronavirus strains COVID-19 COVID-19 pandemic COVID-19 patients CSS CTL Cytokine storm syndrome drug-drug interaction Effectiveness epitope conservation epitope-based vaccines Epitopes evaluated facilitate highlighting implementation in silico Approach induction limit Macrophage observation peptide Probability proinflammatory Protective effects reported Research response risk SARS-CoV-2 SARS-CoV-2 strain selected epitope specificity Support T-cell therapeutic strategy therapy triggered vaccination Vaccine Vaccines while worse prognosis
[DOI] 10.3389/fgene.2021.602196 PMC 바로가기 [Article Type] Genetics

Back to basics in COVID‐19: Antigens and antibodies—Completing the puzzle

COVID-19의 기본으로 돌아가기: 항원과 항체—퍼즐 완성하기

Review

Published on 2021-03-182022-09-10
Journal: Journal of Cellular and Molecular Medicine
[Category] SARS, 변종, 진단,

[키워드] antibodies antibody antigens back battle cellular coronavirus disease Coronavirus disease 2019 counterattack COVID‐19 estimate Evolution Genetic homoeostasis immune memory immune response immune system Immunological memory Infection infectiousness information investigated knowledge lack memory cell Memory cells molecular Molecular diagnosis mutations outbreak Pandemia pathogen Patient persistence Prevalence protective effect Protective effects SARS‐CoV‐2 SARS‐CoV‐2 infection SARS‐CoV‐2 Severe case severe cases stages Task Force tested tests tissue repair treat viability Viral viral infection virus
[DOI] 10.1111/jcmm.16462 PMC 바로가기 [Article Type] Review

Combination of Angiotensin (1-7) Agonists and Convalescent Plasma as a New Strategy to Overcome Angiotensin Converting Enzyme 2 (ACE2) Inhibition for the Treatment of COVID-19

Medicine

Published on 2021-03-182022-10-31
Journal: Frontiers in Medicine
[Category] COVID-19,

[키워드] ACE2 ACE2 antibody ACE2 expression acute respiratory syndrome agonist alleviate Ang II angiotensin Angiotensin (1-7 Angiotensin 1-7 (Ang1-7) angiotensin-converting enzyme 2 antibodies appear approach ARBs AT1R binding block viral entry blocker cardiovascular pathology caused Cell circulating combination therapy concerning convalescent plasma Convalescent plasma (CP) coronavirus correlated COVID-19 COVID-19 patients detrimental effect differential expression Effect elicit expected Health infect Inflammatory response inhibition inhibitor Level lung Lung pathology modulation neutralize neutralizing capacity New pandemic pathogenesis of COVID-19 pathology pharmacological positive cells pro-fibrotic pro-inflammatory protective effect Protective effects receptor recovered patient reduced regimen risk SARS-CoV-2 Spread Strategy Symptoms therapeutic therapy Treatment upregulation viral entry viral infection virus
[DOI] 10.3389/fmed.2021.620990 PMC 바로가기 [Article Type] Medicine

Shared genetic etiology between idiopathic pulmonary fibrosis and COVID-19 severity

특발성 폐섬유증과 COVID-19 중증도 사이의 유전적 병인 공유

Article

Published on 2021-03-012022-09-11
Journal: EBioMedicine
[Category] SARS, 변종, 유전자 메커니즘, 진단, 치료기술,

[키워드] airway airways Analysis association carriers causal variant characterized combined effect complex controls correlation COVID-19 COVID-19 hospitalization COVID-19 Host Genetics Initiative COVID-19 severity determine Effect estimate Evidence excluded explanation fibrosis foundation Genetic genetic association genetic determinant genetic etiology genetic risk factors genetic variants Genome-wide association study GWAS GWAS meta-analysis idiopathic Idiopathic pulmonary fibrosis increased risk initiative instrumental variable instrumental variables IPF Linkage disequilibrium lung Lung disease mendelian randomization MUC5B mucin Mucin. Oak Older Older adults other variants outlier Patient performed Pneumonitis positive protective effect Protective effects provided pulmonary fibrosis risk allele risk factor risk loci risk of COVID-19 SARS-COV-2 infection scarring selection bia Selection bias Self-isolation severe COVID-19 severity survival susceptibility the strongest variance variant were used with COVID-19
[DOI] 10.1016/j.ebiom.2021.103277 PMC 바로가기 [Article Type] Article

Low rate of COVID-19 pneumonia in kidney transplant recipients-A battle between infection and immune response?

신장 이식 환자의 코로나19 폐렴 낮은 발병률-감염과 면역 반응의 전쟁?

Article

Published on 2020-10-012022-09-11
Journal: Transplant infectious disease : an official journa
[Category] SARS, 치료제,

[키워드] Admission age Clinical course Clinical outcome Course COVID-19 COVID-19 pandemic COVID-19 pneumonia CRP cyclosporine cytokine cytokine profile Cytokine storm D-dimer diabetes diagnosed disease severity elevated Eosinopenia Factor Follow-up guide higher risk history hospital immune Immunity immunosuppressive immunosuppressive agent Immunosuppressive agents incidence Infection kidney kidney transplant kidney transplant recipient kidney transplant recipients kidney transplantation. Laboratory LDH lymphopenia Manifestations Modification Mortality N/L N/L ratio outcome Patient Platelet Platelet count Pneumonia positive positive COVID-19 Predictive protective effect Protective effects radiologic recipient rejection rising T-cell the mean transplantation troponin with COVID-19
[DOI] 10.1111/tid.13406 PMC 바로가기 [Article Type] Article

Evaluation of the immunogenicity and protective effects of a trivalent chimeric norovirus P particle immunogen displaying influenza HA2 from subtypes H1, H3 and B

Original Article

Published on 2016-05-252023-06-08
Journal: Emerging Microbes & Infections
[Category] Fulltext, 신종인플루엔자,

[키워드] hemagglutinin 2 Influenza virus Norovirus P particle Protective effects trivalent chimeric immunogen
[DOI] 10.1038/emi.2016.51 PMC 바로가기 [Article Type] Original Article