Efficacy and safety of tofacitinib by background methotrexate dose in psoriatic arthritis: post hoc exploratory analysis from two phase III trialsOriginal Article Published on 2021-09-122024-09-02 Journal: Clinical Rheumatology [Category] 대상포진, [키워드] Disease activity Disease-modifying anti-rheumatic drugs methotrexate psoriatic arthritis Tofacitinib [DOI] 10.1007/s10067-021-05894-2 PMC 바로가기 [Article Type] Original Article
Influence of SARS-CoV-2 Virus Infection on the Course of Psoriasis during Treatment with Biological DrugsObservational Study Published on 2021-08-272022-10-04 Journal: Medicina [Category] MERS, SARS, 임상, [키워드] Administered Affect analyzed Area Biological biological drugs chain comparable control group Course COVID-19 COVID-19 disease COVID-19 pandemic diagnosed drug effective therapy eight Hospitalization index infected with SARS-CoV-2 influence material Mild observé Patient PCR positive psoriasis psoriatic arthritis reaction required Result RT-PCR SARS-CoV-2 SARS-COV-2 infection skin lesions statistically telephone contact therapy time Treatment [DOI] 10.3390/medicina57090881 PMC 바로가기 [Article Type] Observational Study
Pathogenic implications, incidence, and outcomes of COVID-19 in autoimmune inflammatory joint diseases and autoinflammatory disordersReview Published on 2021-07-082022-10-28 Journal: Advances in Rheumatology (London, England) [Category] COVID-19, [키워드] acute respiratory syndrome anti-TNF therapies Autoimmune autoinflammatory disease caused cohorts coronavirus coronavirus disease COVID-19 COVID-19 incidence CVD Cytokine storm syndrome develop diabetes disease Diseases disorder disorders displaying Hospitalization hypertension immunosuppressive Implications incidence increased risk Infection Inflammatory Innate immunity joint Lung disease Male sex monotherapy Older age Other outcome pandemic pathogenic mechanism Patient presence of comorbidity psoriatic arthritis question raised renal rheumatoid arthritis risk factor SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severity shown specific patient group Spondiloarthritis Spread susceptibility Taking therapy virus [DOI] 10.1186/s42358-021-00204-5 PMC 바로가기 [Article Type] Review
A case report of monoarthritis in a COVID-19 patient and literature review Simple actions for complex times6900 Published on 2021-06-112022-10-30 Journal: Medicine [Category] COVID-19, MERS, [키워드] absence affected Arthritis aspecific benefit Case report complex COVID-19 COVID-19 patient diagnosed with COVID-19 Diagnosis diagnostic differential diagnosis individuals Inflammatory arthritis Isolation joint lab lack Like literature review Long-term follow-up Musculoskeletal Nonsteroidal anti-inflammatory drugs oral steroid Patient psoriatic arthritis Reactive arthritis reported SARS-CoV2 SARS-CoV2 infection simple the patient therapy Viral diseases [DOI] 10.1097/MD.0000000000026089 PMC 바로가기 [Article Type] 6900
JAK1 selective inhibitors for the treatment of spondyloarthropathiesSupplement Papers Published on 2021-05-052024-09-04 Journal: Rheumatology (Oxford, England) [Category] 대상포진, [키워드] ankylosing spondylitis axial spondyloarthritis management psoriatic arthritis selective janus kinase inhibitors spondyloarthropathies Treatment [DOI] 10.1093/rheumatology/keaa815 PMC 바로가기 [Article Type] Supplement Papers
Management of particular clinical situations in psoriatic arthritis: an expert’s recommendation document based on systematic literature review and extended Delphi processarticle Published on 2021-05-022024-09-02 Journal: Rheumatology International [Category] 대상포진, [키워드] disease-modifying antirheumatic drugs Manifestations psoriatic arthritis recommendations systematic literature review [DOI] 10.1007/s00296-021-04877-5 PMC 바로가기 [Article Type] article
Use of conventional synthetic and biologic disease-modifying anti-rheumatic drugs in patients with rheumatic diseases contracting COVID-19: a single-center experienceCase Reports Published on 2021-05-012022-10-05 Journal: Rheumatology International [Category] SARS, 임상, [키워드] adjusted affected ankylosing spondylitis Arthritis Autoimmune rheumatic disease biologic changed clinical manifestation clinical response Comorbidity COVID-19 COVID-19 disease course disease course disease-modifying anti-rheumatic drug drug Drug side effect expressed Follow-up General population hospital Inflammatory arthritis investigated Laboratory mild COVID-19 symptoms olfactory dysfunction outcome Patient Pneumonia prospective observational study psoriatic arthritis receiving recorded respiratory symptom rheumatic disease Rheumatoid rheumatoid arthritis SARS-COV-2 infection single-center sore throat spondylitis systemic manifestation treated Treatment [DOI] 10.1007/s00296-021-04818-2 PMC 바로가기 [Article Type] Case Reports
SARS-CoV-2 Infection Induces Psoriatic Arthritis Flares and Enthesis Resident Plasmacytoid Dendritic Cell Type-1 Interferon Inhibition by JAK Antagonism Offer Novel Spondyloarthritis Pathogenesis InsightsSARS-CoV-2 감염은 JAK 길항 작용에 의한 건선성 관절염 발적 및 유착 상주 형질세포양 수지상 세포 유형-1 인터페론 억제를 유도하여 새로운 척추관절염 발병 통찰력 제공Immunology Published on 2021-04-152022-09-11 Journal: Frontiers in Immunology [Category] MERS, 유전자 메커니즘, [키워드] activated Activation antagonism Arthritis arthropathy Blood CD45 CD45+ cells characterized COVID-19 COVID-19 infection CpG DEGs dendritic dendritic cell dendritic cells differentially expressed gene Elevation enthesis evaluate evaluated flare Gene Expression IFNα imiquimod Infection inhibition insight interferon Interferon alpha interferon response investigated Jak JAK/STAT signaling pathway maturation mechanism microbe microbes modulation NF-κB NF-κB signaling normal novel objective occurred Pathway analysis pDC pDCs plasmacytoid dendritic cell plasmacytoid dendritic cells Protein psoriatic arthritis resident Result RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 SARS-CoV2 infection Signaling significantly spondyloarthritis STAT stimulated suppressed therapeutic TLR-7 TNF Tofacitinib Toll-like receptor toll-like receptor signaling Trigger triggered triggers upregulated Viral viral infection was performed [DOI] 10.3389/fimmu.2021.635018 PMC 바로가기 [Article Type] Immunology
Inhibition of Phosphodiesterase-4 in Psoriatic Arthritis and Inflammatory Bowel DiseasesReview Published on 2021-03-052024-09-02 Journal: International Journal of Molecular Sciences [Category] 대상포진, [키워드] apremilast CAMP enteropathic spondyloarthritis inflammatory bowel diseases phosphodiesterase-4 psoriatic arthritis ulcerative colitis [DOI] 10.3390/ijms22052638 PMC 바로가기 [Article Type] Review
Furin Expression in Patients With Psoriasis—A Patient Cohort Endangered to SARS-COV2?Medicine Published on 2021-02-102022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ACE2 ACE2 expression analyzed Angiotensin converting enzyme-2 Arthritis baseline biologic blood cell Blood cells blood sample clinical clinical trial Control controls Course COVID-19 decreased expression Endangered enzyme evaluate Express expression expression level expression levels Follow-up furin host cell in viral induce Infection mRNA expression not differ overexpressed Patient patients patients treated psoriasis psoriatic arthritis raised reduce registry retrieved risk SARS-CoV-2 Secukinumab severe COVID-19 significantly significantly increased therapeutic intervention translational Treatment treatment initiation untreated patients ustekinumab [DOI] 10.3389/fmed.2021.624462 PMC 바로가기 [Article Type] Medicine