randomised controlled trial – Page 4 – Communicable Diseases Research

Beneficial non-specific effects of live vaccines against COVID-19 and other unrelated infections

Review article

Published on 2022-08-262022-10-05
Journal: The Lancet. Infectious Diseases [Category] 임상,

Women’s EmotionS, Trauma and EmpowErMent (W-ES.T.EEM) study protocol: a psychoeducational support intervention for victims of domestic violence – a randomised controlled trial

Article

Published on 2022-08-252022-10-05
Journal: BMJ Open [Category] 임상,

[키워드] Administered adult psychiatry Affect anonymously approach approved articles behavioural blind center change control condition COVID-19 COVID-19 outbreak COVID-19 pandemic Efficacy Ethics ethics committee experimental group face-to-face interventions family Intervention Intimate partner violence Italy manuscript Mental online psychological intervention participant peer-reviewed physical prevented protocol psychoeducational Psychoeducational intervention randomised controlled trial Randomly receiving recruited reported Research Study protocol Support Telemedicine therapy treatment as usual university widespread women written Informed Consent
[DOI] 10.1136/bmjopen-2021-060672 PMC 바로가기 [Article Type] Article

Prevention and early treatment of the long-term physical effects of COVID-19 in adults: design of a randomised controlled trial of resistance exercise-CISCO-21

Randomized Controlled Trial

Published on 2022-08-152022-10-05
Journal: Trials [Category] SARS, 임상,

[키워드] Admission breathlessness cause chest pain Contact Controlled clinical trial COVID COVID-19 COVID-19 infection diagnosis of COVID-19 discharged Dyspnoea early treatment Effect Ethical approval ethics committee Exercise capacity fatigue frailty group Health Health status healthcare professionals hospital hospitalisation hospitalised Infection Intervention Long Long COVID National Health Service NHS participant Patient personalised physical physical activity Pragmatic prevention Primary outcome problem Quality of life questionnaire randomisation randomised randomised controlled trial REC recruitment Registered rehabilitation resistance resistance exercise SARS-CoV-2 secondary outcome spirometry Symptom syndrome therapy Two-arm usual care West
[DOI] 10.1186/s13063-022-06632-y PMC 바로가기 [Article Type] Randomized Controlled Trial

Effect of interleukin-6 receptor antagonists in critically ill adult patients with COVID-19 pneumonia: two randomised controlled trials of the CORIMUNO-19 Collaborative Group

COVID-19 폐렴이 있는 위독한 성인 환자에서 인터루킨-6 수용체 길항제의 효과: CORIMUNO-19 공동 그룹의 2건의 무작위 대조 시험

Article

Published on 2022-08-102022-09-11
Journal: The European Respiratory Journal [Category] Fulltext, SARS, 임상,

[키워드] 95% CI antagonist anti-IL-6 receptor assigned Bayesian clinical trials clinically controlled clinical trials coronavirus disease Coronavirus disease 2019 COVID-19 credible interval CrI Critically ill Critically ill patient critically ill patients determine Effect events group hazard ratio IMPROVE indicated interleukin-6 receptor intravenously investigator-initiated mechanical ventilation median multicentre NIV Noninvasive ventilation not need numbers of patient Open-label outcome Patient patients with COVID-19 Pneumonia posterior probability randomised randomised controlled randomised controlled trial Randomly receive receptor risk of death SARI sarilumab significantly TCZ TOCI Tocilizumab Trial usual care with COVID-19
[DOI] 10.1183/13993003.02523-2021 PMC 바로가기 [Article Type] Article

Should RECOVERY have used response adaptive randomisation? Evidence from a simulation study

Randomized Controlled Trial

Published on 2022-08-062022-10-04
Journal: BMC Medical Research Methodology [Category] SARS, 임상,

[키워드] adaptive adaptive randomisation Adaptive trial Arm ARMS Care Community coronavirus COVID-19 COVID-19 mortality COVID-19 therapy defined Dexamethasone effective error rate estimate exhibiting FIVE fixed form hospitalised Hydroxychloroquine induce Lopinavir-ritonavir lower mortality Measures mortality rate other diseases Patient patient death patient subgroup performed Platform trial question randomisation randomised controlled trial Randomised Evaluation receiving recovery RECOVERY trial reduced reducing reduction REMAP-CAP representing Respiratory Support Response-adaptive randomization Simulation standard care Statistical power tested Treatment Trial Two-arm
[DOI] 10.1186/s12874-022-01691-w PMC 바로가기 [Article Type] Randomized Controlled Trial

Video meeting signals: Experimental evidence for a technique to improve the experience of video conferencing

Randomized Controlled Trial

Published on 2022-08-032022-10-05
Journal: PLoS ONE [Category] 임상,

[키워드] added All participant benefit carried coded controls disrupt Evidence experiment fatigued group groups IMPROVE information Interaction less limitation limitations lockdowns meeting outcome overcome positive Psychological psychological problem randomised controlled trial replicated signal significantly higher social interaction transcript were given
[DOI] 10.1371/journal.pone.0270399 PMC 바로가기 [Article Type] Randomized Controlled Trial

Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial

ChAdOx1 nCoV-19 또는 BNT162b2 2회 접종 및 BNT162b2(COV-BOOST) 3차 접종 후 4차 접종으로 제공된 BNT162b2 및 mRNA-1273 COVID-19 백신의 안전성, 면역원성 및 반응성: 다기관, 맹검, 단계 2, 무작위 시험

Clinical Trial

Published on 2022-08-012022-09-11
Journal: The Lancet. Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 변종, 임상, 진단,

[키워드] 1:1 95% CI adverse event All participants analysed anti-spike protein IgG assigned blinded block size BNT162b2 boost booster Booster vaccine cellular Cellular and humoral immunity Cellular immune response ChAdOx1 nCoV-19 computer-generated Concentration Controlled trial country COV-BOOST COVID-19 COVID-19 vaccine COVID-19 vaccines dose doses Effectiveness ELISA ELISPOT Endpoint enrolled fatigue female Fold change Fold changes force geometric geometric mean groups Humoral immunity immunogenicity Intramuscular injection IQR ISRCTN Laboratory Local male median age median interval Moderna modified intention-to-treat mRNA mRNA-1273 mRNA-1273 booster mRNA-1273 COVID-19 vaccine multicentre of BNT162b2 outcome participant peak per-protocol population Pfizer-BioNTech Phase 2 random randomisation list randomised controlled trial Randomised trial Randomly reactogenicity receive Registered reported representing response Safety SARS-CoV-2 screened Serious Adverse Event seronegative participant seronegative participants serostatus Seven significant increase statistician T-cell Response T-cell responses Task Force the vaccine the vaccines titre treatment allocation Trial upper arm Vaccine variant were assessed wild-type
[DOI] 10.1016/S1473-3099(22)00271-7 PMC 바로가기 [Article Type] Clinical Trial

Comparison of telecardiac rehabilitation with centre-based cardiac rehabilitation and usual care: a protocol for systematic review including a meta-analysis

Article

Published on 2022-08-012022-11-16
Journal: Open Heart [Category] meta-analysis, SARS,

[키워드] 95% CI Acute coronary syndrome Analysis article articles assessment cardiac cardiac disease Cardiac rehabilitation Case series cause collected college Contact COVID-19 criteria cross-over database development disease Egger estimate Ethics Evidence feasibility functional heart failure heterogeneity include independent intervention arm item mean difference measure Meta-analysis Microsoft Excel morbidity morbidity and mortality Mortality not significant observational study Older outcome oxygen uptake pandemic per-protocol performed PROSPERO protocol Publication bia Quality of life random-effects model randomised randomised controlled trial RCT RCTs reducing rehabilitation reported Reporting Result review SARS-CoV-2 selected sensitivity analysis Stata SE Station study period subject systematic review Systematic Reviews as Topic Telemedicine the patient trials USA used to calculate usual care
[DOI] 10.1136/openhrt-2022-002018 PMC 바로가기

Delayed intubation is associated with mortality in patients with severe COVID-19: A single-centre observational study in Switzerland

Observational Study

Published on 2022-08-012022-10-04
Journal: Anaesthesia, critical care & pain medicine [Category] 임상,

Online cognitive behavioural therapy as a psychological vaccine against stress during the COVID-19 pandemic in pregnant women: A randomised controlled trial

Randomized Controlled Trial

Published on 2022-08-012022-10-05
Journal: Journal of psychiatric research [Category] Coronavirus, 임상,