Evolution of Diploid Progenitor Lung Cell Applications: From Optimized Biotechnological Substrates to Potential Active Pharmaceutical Ingredients in Respiratory Tract Regenerative MedicineReview Published on 2021-09-242022-10-31 Journal: Cells [Category] COVID-19, SARS, [키워드] active pharmaceutical ingredient administration Allogeneic API approach Burn Cell cell banking Cell therapy cell type COVID-19 COVID-19 patient diploid diploid progenitor cells effective effort Evolution FIVE function GMP good manufacturing practice homologous inflammatory lung disease ingredient Local lung lung cell lung cells lung tissue management Medicine MRC-5 cells Patient platform Potential produced progenitor progenitor cell recent regenerative regenerative medicine Research respiratory respiratory tract Safe substrate substrates Symptom syndrome therapeutic therapeutic use therapy tract Vaccine vaccine production vaccine substrate [DOI] 10.3390/cells10102526 PMC 바로가기 [Article Type] Review
First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol아급성 완전 척수 손상에서 iPSC 유래 NS/PC 이식의 인간 최초 임상 시험: 연구 프로토콜Article Published on 2021-09-072022-09-11 Journal: Regen Ther [Category] 비임상, [키워드] application approach approved breath Cell cell differentiation center clinical clinical study clinical trial clinical trials Committee Complete conducted Consent COVID-19 epidemic dose-escalation effective Efficacy Evidence evidence of experiment follow-up period Good Immunosuppression induced induced pluripotent stem cells inhibitor initial Injury Japan Japanese Kyoto labor life Medicine Ministry of Health Mouse models network Neural Neural stem/progenitor cells neurological function Open-label organized outcomes Patient pluripotent stem cells preclinical study preliminary evidence primary focus promote protocol quality checks receive recruited regenerative medicine registry Safe single-arm design spinal cord Spinal cord injury stock Study protocol transplantation Treatment university Welfare [DOI] 10.1016/j.reth.2021.08.005 PMC 바로가기 [Article Type] Article
Pericytes: Intrinsic Transportation Engineers of the CNS MicrocirculationPhysiology Published on 2021-08-232022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] Activation Alzheimer’s disease blood flow blood-brain barrier Brain capillary network cellular CNS contractile proteins Engineer function functional hyperemia identify identity Immune homeostasis mice Microcirculation neuronal Neurovascular neurovascular coupling oxygen pericyte pericytes positioned progeny regenerative medicine respond stroke subtype Therapeutic strategies [DOI] 10.3389/fphys.2021.719701 PMC 바로가기 [Article Type] Physiology
Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative MedicineReview Published on 2021-08-012022-10-31 Journal: Cells [Category] COVID-19, [키워드] activities Angiogenesis application biological property Brain candidate cardiovascular disease cell differentiation cell surface receptors cell type cellular contribute COVID-19 Cytokines Enzymes Exosome exosome biogenesis Exosomes extracellular space Extracellular vesicles facilitate function functions Growth factors highlight immune Intercellular communication Isolation knowledge lipids Medicine Mesenchymal stem cells microRNA MicroRNAs modulation molecular multivesicular bodies nucleic acids paracrine plasma membrane produced proliferation Proteins regenerative regenerative medicine released secreted Signaling stability STEM Stress therapy tissue tissue regeneration Toxicity transcription factors Traumatic brain injury Vesicle wound healing [DOI] 10.3390/cells10081959 PMC 바로가기 [Article Type] Review
Gazing Long into a Clinical and Social Abyss? Treating Hypertrophic Scarring and KeloidsArticle Published on 2021-08-012023-06-12 Journal: Rejuvenation Research [Category] MERS, [키워드] Dermatology Drug development hypertrophic scars keloids regenerative medicine [DOI] 10.1089/rej.2021.0037 PMC 바로가기
The role of mesenchymal stem/stromal cells in the acute clinical settingArticle Published on 2021-08-012023-07-12 Journal: The American journal of emergency medicine [Category] SARS, [키워드] cell transplantation regenerative medicine stem cells [DOI] 10.1016/j.ajem.2020.11.035
Anticipated impact of stem cell and other cellular medicine clinical trials for COVID-19COVID-19에 대한 줄기 세포 및 기타 세포 의학 임상 시험의 예상 영향Short Communication Published on 2021-06-112022-09-10 Journal: Regenerative Medicine [Category] MERS, SARS, 임상, [키워드] analyzed average Cell Cell therapy cellular cellular medicine clinical trial clinical trials collected COVID-19 criteria Critical defined effective Evidence material MOST MSCs regenerative medicine Safe stem cell Stem cell therapy stem cells therapy Treatment treatments for COVID-19 Trial [DOI] 10.2217/rme-2021-0025 PMC 바로가기 [Article Type] Short Communication
COVID-19 Impact on Musculoskeletal Regenerative Medicine Research: Maintaining Lab ContinuityArticle Published on 2021-06-052022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] activities activity Analysis assumed concerning continuity control measures COVID-19 COVID-19 diffusion COVID-19 emergency COVID-19 pandemic Effect eliminating greater handling hazard hierarchy Impact knowledge lab maintain maintaining measure Medicine mitigate Musculoskeletal operator Outbreaks pandemic physical Prevent regenerative regenerative medicine Research researcher Result risk Risk assessment risk of COVID-19 Safe SARS-CoV-2 social distancing therapeutic strategy tissue translation Ventilation work [DOI] 10.3390/ijerph18116110 PMC 바로가기 [Article Type] Article
Human Platelet Lysate for Good Manufacturing Practice-Compliant Cell ProductionReview Published on 2021-05-132023-08-30 Journal: International Journal of Molecular Sciences [Category] E형 간염, [키워드] Cell therapy good manufacturing practice (GMP) human platelet lysate (HPL) platelet concentrates regeneration regenerative medicine [DOI] 10.3390/ijms22105178 PMC 바로가기 [Article Type] Review
Stem cell therapies and benefaction of somatic cell nuclear transfer cloning in COVID-19 era코로나19 시대의 줄기세포 치료제와 체세포 핵이식 복제의 장점Review Published on 2021-05-122022-09-12 Journal: Stem Cell Research & Therapy [Category] SARS, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome Anti-inflammatory antivirals ARDS being benefit Bio-pharming boost caused Cell cell type Cell-based therapy cellular Clinical studies cloned COVID-19 COVID-19 patient COVID-19 patients damage dependence develop Drug testing Embryo embryonic embryos generate Genome reprogramming Health health emergency immunomodulatory effect immunomodulatory effects Interaction mesenchymal stem cell Mesenchymal stem cells MSC MSCs nuclear organ Organoid organoids potential benefit potential benefits prominence regenerative regenerative medicine Research respiratory distress Respiratory distress syndrome SARS-CoV-2 SARS-COV-2 infection SCNT somatic cell STEM stem cell stem cells structures syndrome therapeutic Therapies therapy transfer transgenic treat unique Vaccinations Vascular [DOI] 10.1186/s13287-021-02334-5 PMC 바로가기 [Article Type] Review