University population-based prospective cohort study of SARS-CoV-2 infection and immunity (SARSSURV-ULiège): a study protocolSARS-CoV-2 감염 및 면역에 대한 대학 인구 기반 전향적 코호트 연구(SARSSURV-ULiège): 연구 프로토콜Article Published on 2022-01-252022-09-11 Journal: BMJ Open [Category] SARS, 진단, 치료기술, [키워드] activity All participant All participants Antibody Response Antibody responses Antibody testing approval blood sample Blood samples cohort study collected Complete COVID-19 COVID-19 pandemic detect determine Epidemiology Ethics ethics committee Evidence flexible higher education immune response Immunity immunology incidence Infection lack magnitude management medical histories MONITOR Neutralising Antibodies neutralising antibody participant Phase 1 Phase 2 population-based cohort positive Potential Prevalence profiles prospective cohort study protocol amendment public health questionnaire Rapid test rapid test result reference number Registered required Research Research Ethics Research Ethics Committee respond risk Risk assessment Risk management RT-qPCR Safe Saliva SARS-CoV-2 SARS-CoV-2 antibody testing SARS-COV-2 infection serological serological test Seroprevalence Stage student study period Study protocol submitted university university hospital vaccination Vaccine hesitancy Weekly [DOI] 10.1136/bmjopen-2021-055721 PMC 바로가기 [Article Type] Article
The Canadian National Vaccine Safety Network: surveillance of adverse events following immunisation among individuals immunised with the COVID-19 vaccine, a cohort study in Canada캐나다 국립백신안전네트워크(Canadian National Vaccine Safety Network): 캐나다 코호트 연구인 COVID-19 백신으로 예방접종을 받은 개인의 예방접종 후 부작용 감시Article Published on 2022-01-202022-09-11 Journal: BMJ Open [Category] Coronavirus, SARS, 치료기술, [키워드] 95% CI 95% CIs Active surveillance adverse event age approval board Breastfeeding calculated Calgary Canada cohort study Conjoint Health Research Ethics Board COVID-19 vaccine COVID-19 vaccines dose Epidemiology Ethics event groups Health healthy Immunocompromised individual manuscript MONITOR network Older peer-reviewed PEI Population pregnant produced provide public health rate ratio Research Research Ethics research methods Safety Sex Statistics statistics & Surveillance telephone Toronto UBC university Vaccine website Weekly [DOI] 10.1136/bmjopen-2021-051254 PMC 바로가기 [Article Type] Article
Double-blind placebo-controlled randomized clinical trial to assess the efficacy of montelukast in mild to moderate respiratory symptoms of patients with long COVID: E-SPERANZA COVID Project study protocol장기간 COVID-19 환자의 경증에서 중등도의 호흡기 증상에 대한 몬테루카스트의 효능을 평가하기 위한 이중 맹검 위약 대조 무작위 임상 시험: E-SPERANZA COVID 프로젝트 연구 프로토콜Study Protocol Published on 2022-01-062022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 acute phase Affect Ageusia Analysis Anosmia approved assessment asthenia Awareness Brain Clinical research clinical trial clinician Confusion control group COPD coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 symptom COVID-19 symptoms defined Desaturation disabling symptoms dissemination double-blind Dyspnea effective Efficacy Ethics ethics committee EudraCT evaluate evaluate the effect Exercise capacity exertion explained functional Functional status globe headache Health Health status healthcare include Infection Intervention life Likert scale Long COVID Mental mental confusion Mild mild to moderate moderate Montelukast Mortality objective Open Access oxygen oxygen saturation pandemic participant pathophysiology Patient patients with SARS-CoV-2 peer-reviewed phase Placebo placebo group placebo-controlled primary care Primary outcome professionals Quality of life questionnaire Randomized randomized clinical trial Randomized controlled trial Randomly reference number Registered Research Ethics respiratory respiratory symptom respiratory symptoms SARS-CoV-2 SARS-COV-2 infection Secondary objectives Secondary outcomes sick Side effect Study protocol subgroup of patient Test the SARS-CoV-2 Treatment Trial Trial registration while [DOI] 10.1186/s13063-021-05951-w PMC 바로가기 [Article Type] Study Protocol
Allocation of Opportunities to Participate in Clinical Trials during the Covid-19 Pandemic and Other Public Health Emergencies코로나19 팬데믹 및 기타 공중 보건 비상 상황에서 임상 시험에 참여할 수 있는 기회 할당Article Published on 2022-01-012022-09-11 Journal: The Hastings Center report [Category] 임상, [키워드] allocation approach clinical clinical trial clinical trials COVID-19 Emergency Guidance hospital medical need offer opportunity Other pandemic Patient Public public health public health emergency raised recruitment Research Research Ethics scarcity Support therapeutic interventions Trial trial recruitment. [DOI] 10.1002/hast.1297 PMC 바로가기 [Article Type] Article
SARS-CoV-2 challenge studies: ethics and risk minimisationCurrent Controversy Published on 2021-12-252022-10-30 Journal: Journal of medical ethics [Category] COVID-19, [키워드] accelerate approach assessment cause clinical implication clinical trials COVID-19 COVID-19 incidence criteria Critical develop effective effective vaccine epidemiological Ethics evaluate exceptional global public health healthy volunteer human infection infecting pathway raised Recognition Research Research Ethics risk SARS-CoV-2 scientific research Treatment virus [DOI] 10.1136/medethics-2020-106504 PMC 바로가기 [Article Type] Current Controversy
Lessons Learned: Beta-Testing the Digital Health Checklist for Researchers Prompts a Call to Action by Behavioral ScientistsViewpoint Published on 2021-12-222022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, SARS, [키워드] access Action approach assist behavioral medicine benefit bioethics checklist COVID-19 data management Digital Digital health Effectiveness example Guidance Health identify Influenza institutional review board Intervention involved IRB lesson mHealth mobile phone offer outbreak participant potential risk privacy public health recommendation Research Research Ethics researcher responsible risk risks and benefits Safe scientist social media Support Surveillance unique Usability variety was used wearable sensors [DOI] 10.2196/25414 PMC 바로가기 [Article Type] Viewpoint
CTN 328: immunogenicity outcomes in people living with HIV in Canada following vaccination for COVID-19 (HIV-COV): protocol for an observational cohort studyArticle Published on 2021-12-162022-10-05 Journal: BMJ Open [Category] SARS, 임상, [키워드] adjuvant AIDS Analysis antibody approval Canada CD4 CD4 count Cell-mediated immune responses clinical trials cohort study Comorbidities Comorbidity Control controls COVID-19 COVID-19 vaccine described determine dose driving enrolment Ethics Factor FIVE HIV HIV & HIV-negative HIV-uninfected immune response immunogenicity outcome immunology IMPROVE include individuals inflammatory markers Montreal MOST Multimorbidity Observational cohort study participant PLWH PLWH cohort primary end point protocol receiving Regression Research Research Ethics STOP study participant suppressed T cell T cell phenotype Toronto vaccination Vaccine vaccine dose Viral load Virology with HIV written Informed Consent [DOI] 10.1136/bmjopen-2021-054208 PMC 바로가기 [Article Type] Article
Evaluation of new or repurposed treatments for COVID-19: protocol for the phase Ib/IIa DEFINE trial platformCOVID-19에 대한 신규 또는 용도 변경 치료제 평가: Ib/IIa상 DEFINE 시험 플랫폼 프로토콜Article Published on 2021-12-152022-09-11 Journal: BMJ Open [Category] 임상, [키워드] acceptance adaptive administration Analysis Appropriate approval Arm ARMS assisted ventilation caused changes in clinical trial Coagulation Cohort Community Complete computer COVID-19 COVID-19 therapy dependent on development during treatment effective Efficacy Ethics ethics committee EudraCT Evidence evidence of Experimental medicine exploratory Follow-up hospital Hospital stay hospitalised patient Infection Infectious diseases information initial mechanism mechanism of action Medicine MHRA National Health Service NEWS2 NHS Novel coronavirus Open-label Ordinal Scale oxygen Oxygen requirements participant Pathways Patient patient cohorts patient safety patients with COVID-19 peer-reviewed pharmacokinetic Pneumonia Pneumonitis positive present product protocol randomisation randomised Randomised Evaluation REC recovery recruited recruitment registration number research and development Research Ethics Research Ethics Committee respiratory medicine (see thoracic medicine) Safe SARS-CoV-2 score secondary Standard of care statistical analysis submitted Support Therapeutics therapy Thoracic Treatment treatment arm treatment period Trial trial platform variable Viral load viral-induced WHO ordinal scale [DOI] 10.1136/bmjopen-2021-054442 PMC 바로가기 [Article Type] Article
Functional recovery following hospitalisation of patients diagnosed with COVID-19: a protocol for a longitudinal cohort studyCOVID-19 진단을 받은 환자의 입원 후 기능 회복: 종단적 코호트 연구를 위한 프로토콜Multicenter Study Published on 2021-12-132022-09-11 Journal: BMJ Open [Category] SARS, 변종, [키워드] activity acute infection Admission age approved assessment board clinical clinical care conducted COREG COVID-19 COVID-19 illness determinant determinants diagnosed diagnosed with COVID-19 discharge disseminate Effect Epidemiology Ethics Evidence fatigue FIVE frailty functional guidelines Health crisis hospital hospital discharge hospitalisation hospitalised hospitals individual Infection Inpatient International international public health limitation linear longitudinal cohort study Lung function management measure medium minimum multicentre National Older outcome participant Patient peer-reviewed physical platform Primary outcome protocol protocols protocols & registration number registry regression analysis rehabilitation rehabilitation medicine Research Ethics scale Sepsis serious COVID-19 Subgroup analyses subgroup analysis survivor trajectory variants variants of concern website with COVID-19 [DOI] 10.1136/bmjopen-2021-053021 PMC 바로가기 [Article Type] Multicenter Study
Going Viral: Researching Safely on Social MediaViewpoint Published on 2021-12-132022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, SARS, [키워드] addressed adverse events Bullying COVID-19 pandemic cyber bullying dissemination effective Guidance Health help management media Mental Occupational safety offer online bullying participant physical recruit recruitment Research research activities Research Ethics researcher response risk Safe Safety social media students web-based platform [DOI] 10.2196/29737 PMC 바로가기 [Article Type] Viewpoint