At-home sample collection is an effective strategy for diagnosis and management of symptomatic and asymptomatic SARS-CoV-2 carriers재택 검체 채취는 유증상 및 무증상 SARS-CoV-2 보균자의 진단 및 관리를 위한 효과적인 전략입니다.Article Published on 2022-05-092022-09-11 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI Adults Analysis Asymptomatic Asymptomatic cases average carrier case-control study Collection Community COVID-19 cross-sectional determine Diagnosis diagnostic testing disease effective handling home humans individual lower risk management molecular nasal swab National no symptom no symptoms participant PCR test positive positive test result Prevalence prevalence of COVID-19 provide Relative risk retrospective risk risk ratio RT-PCR test SARS-CoV-2 SARS-CoV-2 tests self-reported symptom Self-reported symptoms specimen handling Symptom symptomatic and asymptomatic symptomatic individual symptomatic individuals the United State Transmission transmission of SARS-CoV-2 United States [DOI] 10.1186/s12879-022-07377-4 PMC 바로가기 [Article Type] Article
Efficacy and safety of tocilizumab versus standard care/placebo in patients with COVID-19; a systematic review and meta-analysis of randomized clinical trialsCOVID-19 환자에서 표준 치료/위약 대비 토실리주맙의 효능 및 안전성 무작위 임상 시험의 체계적인 검토 및 메타 분석Review Published on 2022-05-012022-09-11 Journal: British Journal of Clinical Pharmacology [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 95% CI adverse event all-cause mortality assessment Bia carried certainty certainty of evidence clinical trial controlled trials coronavirus coronavirus disease COVID-19 COVID-19 patient Critical data extraction Efficacy Efficacy and safety evaluate evaluated event events incidence include mechanical ventilation Meta-analysis methodology moderate Mortality nine Patient patients with COVID-19 peer-reviewed progression Randomized randomized clinical trial Randomized controlled trial RCT RCTs reduce reported responsible risk Risk of bias risk ratio SAE searched Serious Adverse Events systematic review therapy Tocilizumab tocilizumab administration variety [DOI] 10.1111/bcp.15124 PMC 바로가기 [Article Type] Review
Janus kinase inhibitors for hospitalized patients with COVID-19: a meta-analysis of randomized controlled trialsCOVID-19로 입원한 환자를 위한 Janus kinase inhibitors: 무작위 대조 시험의 메타 분석Meta-Analysis Published on 2022-05-012022-09-11 Journal: Expert review of anti-infective therapy [Category] COVID19(2023년), SARS, 임상, [키워드] 28-day mortality 95% CI adverse event adverse events can be used Clinical efficacy Clinical improvement clinical outcomes Cochrane Library control group COVID-19 exhibited extracorporeal membrane oxygenation help hospitalized patient hospitalized patients improve clinical outcome Infection inhibitor investigated Jak JAK inhibitor jak inhibitors janus Janus kinase Janus kinase inhibitor Kinase inhibitor less mechanical ventilation Meta-analysis Mortality mortality rate OVID Patient Placebo placebos Randomized controlled trial Randomized controlled trials RCT RCTs receiving reduce mortality risk risk ratio SARS-CoV-2 searched study group the study group Treatment Web of Science with COVID-19 [DOI] 10.1080/14787210.2022.2004120 PMC 바로가기 [Article Type] Meta-Analysis
Seroprevalence of SARS-CoV-2 antibodies and reduced risk of reinfection through 6 months: a Danish observational cohort study of 44 000 healthcare workersSARS-CoV-2 항체의 혈청 유병률 및 6개월 동안 재감염 위험 감소: 44,000명의 의료 종사자를 대상으로 한 덴마크 관찰 코호트 연구Observational Study Published on 2022-05-012022-09-12 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95%CI acute respiratory syndrome antibody Characteristics coronavirus disease Coronavirus-2 COVID COVID-19 ELISA examined HCW HCWs healthcare worker Healthcare workers immune response increased risk infection with SARS-CoV-2 key factor longitudinal change majority Observational cohort study offered Older participant Prospective Study protective effect Questionnaires reduced risk Registered Reinfection remained reported risk risk ratio RRs SARS-CoV-2 SARS-CoV-2 antibody screened seropositive seropositive participants Seropositivity Seroprevalence significantly higher significantly increased significantly lower Symptom [DOI] 10.1016/j.cmi.2021.09.005 PMC 바로가기 [Article Type] Observational Study
Clinical efficacy and safety of high-flow nasal cannula (HFNC) in acute hypoxaemic patients with COVID-19: a protocol for a systematic review and meta-analysisCOVID-19를 가진 급성 저산소병 환자에서 고유 유량 코 캐뉼라 (HFNC)의 임상 효능 및 안전성 : 체계적인 검토 및 메타 분석을위한 프로토콜Article Published on 2022-04-122022-08-31 Journal: BMJ Open [Category] meta-analysis, [키워드] Acute respiratory failure adult intensive & age and sex approach Caregivers clinical Clinical efficacy Cochrane Library Continuous data COVID-19 COVID-19 patient COVID-19 patients Critical Critical care data extraction determine develop disease severity Efficacy and safety eligibility criteria Ethical approval Ethics evaluate for inclusion HFNC High-flow nasal cannula hypoxaemic respiratory failure identify increased risk Infection transmission infections Intensive intensive care intensive care unit intubation mean difference meta-analyses Meta-analysis Mortality nasal nasal cannula outcome Participants Patient peer-reviewed performed Primary outcome PROSPERO protocol randomised controlled trial RCT RCTs registration number required respiratory Respiratory failure respiratory infections risk risk of bia risk ratio secondary outcome Secondary outcomes Subgroup analyses subgroup analysis systematic review the mean Treatment undergo Web of Science [DOI] 10.1136/bmjopen-2021-057743 PMC 바로가기 [Article Type] Article
Risk of adverse events after covid-19 in Danish children and adolescents and effectiveness of BNT162b2 in adolescents: cohort study덴마크 어린이 및 청소년에서 코로나19 이후 부작용 위험과 청소년에서 BNT162b2의 효과: 코호트 연구Article Published on 2022-04-112022-09-11 Journal: The BMJ [Category] COVID19(2023년), SARS, 변종, [키워드] 95% confidence interval adjusted analyses adverse event adverse events BNT162b2 BNT162b2 mRNA vaccine Chain Reaction children Cohort cohort study complications Contact delta variant Denmark disorders dominant variant dose drug treatment effective Effectiveness Encephalitis evaluate evaluated first dose FIVE general practitioner General practitioners Guillain-barrè syndrome Health Service healthcare hospital Hospital admission Hospital admissions ICU increase in Infection Inflammatory intensive care intensive care unit MIS-C myocarditis occurred of BNT162b2 outcome participant Pfizer-BioNTech polymerase chain polymerase chain reaction positive Practitioner recipient reducing reverse transcriptase Reverse transcriptase polymerase chain reaction risk risk ratio RT-PCR SARS-CoV-2 SARS-COV-2 infection second dose study period Symptoms syndrome tested transcriptase Treatment Vaccine variant [DOI] 10.1136/bmj-2021-068898 PMC 바로가기 [Article Type] Article
Fluvoxamine for Outpatient Management of COVID-19 to Prevent Hospitalization: A Systematic Review and Meta-analysis입원 예방을 위한 COVID-19 외래 환자 관리를 위한 Fluvoxamine: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-04-012022-09-11 Journal: JAMA Network Open [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI all-cause hospitalization Analysis antivirals association Bayesian Bia clinical clinical trials conducted COVID-19 data extraction demographics doses Effectiveness Efficacy estimate estimates evaluate Evidence fluvoxamine Health Organization Hospitalization inclusion criteria individual management Meta-analysis moderate monoclonal antibody monoclonal antibody therapy Neutral outcome Outpatient outpatients Participants patients Placebo Prevent Probability random effect random-effect randomized clinical trial randomized trial ranged reduced registry review risk risk ratio SARS-CoV-2 scenario synthesis systematic review therapy Trial trials variety with COVID-19 World Health Organization [DOI] 10.1001/jamanetworkopen.2022.6269 PMC 바로가기 [Article Type] Meta-Analysis
Association of Subcutaneous or Intravenous Administration of Casirivimab and Imdevimab Monoclonal Antibodies With Clinical Outcomes in Adults With COVID-19카시리비맙 및 임데비맙 단클론항체의 피하 또는 정맥내 투여와 COVID-19가 있는 성인의 임상 결과와의 연관성Article Published on 2022-04-012022-09-12 Journal: JAMA Network Open [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI adjusted administer Administered administration Admission adverse events age antibody association Casirivimab clinical clinically cohort study Control control group COVID-19 death decrease eligible eligible patient Emergency use authorization end point evaluate evaluated Evidence expand health system Hospitalization Imdevimab injection intensive care intravenous mAb mechanical ventilation Mild moderate Moderate COVID-19 no difference outcome Outpatient Patient patients patients treated Primary outcome prospective cohort study randomized clinical trial reduced risk risk ratio secondary single dose statistically Subcutaneous subcutaneous administration subcutaneously Symptom Symptoms Treatment women [DOI] 10.1001/jamanetworkopen.2022.6920 PMC 바로가기 [Article Type] Article
Impact of prior vaccination with Covishield TM and Covaxin® on mortality among symptomatic COVID-19 patients during the second wave of the pandemic in South India during April and May 2021: a cohort study2021년 4월과 5월에 남인도에서 2차 대유행 기간 동안 Covishield TM 및 Covaxin®을 사용한 사전 예방 접종이 증상이 있는 COVID-19 환자의 사망률에 미치는 영향: 코호트 연구Article Published on 2022-03-182022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval Adjusted analysis Admission age Astra Zeneca circulation Cohort cohort study Corona Corona virus COVAXIN® COVID-19 COVID-19 patient COVID-19 patients COVID-19 vaccine COVID-19 vaccines COVISHIELDTM dose doses Emergency use evaluated expressed greater Hospitalization ICU ICU admission Impact impacted indeterminate India intensive care intensive care unit mitigate Mortality NIV non-invasive ventilation Oxford oxygen Oxygen therapy pandemic Patient patients presenting Primary outcome reduced risk risk ratio RT-PCR second wave severity severity of illness south India symptomatic vaccination Vaccine variant were assessed widespread [DOI] 10.1016/j.vaccine.2022.02.023 PMC 바로가기 [Article Type] Article
Decreased risk of COVID-19 pneumonia in children and adolescents during the Delta variant emergence델타 변이형 출현 동안 어린이 및 청소년의 COVID-19 폐렴 위험 감소Article Published on 2022-03-012022-09-11 Journal: Public health [Category] SARS, 변종, [키워드] 95% CI 95% confidence interval Adolescent Analysis analyzed association B.1.617.2 Child children Chronic kidney disease CIs cohort study Comorbidity conducted COVID-19 COVID-19 pneumonia Decreased Delta delta variant diabetes Diabetes Mellitus evaluate evaluated Factor identify Immunosuppression incidence rate increased risk Kidney disease laboratory-confirmed malignant tumors obesity older patient older patients Other Patient Pneumonia reduced risk Research retrospective risk risk of COVID-19 risk ratio risk ratios RRs SARS-CoV-2 severe COVID-19 manifestations variant were used [DOI] 10.1016/j.puhe.2021.12.017 PMC 바로가기 [Article Type] Article