Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell lineResearch Article Published on 2019-01-082023-08-29 Journal: BMC Genomics [Category] E형 간염, [키워드] Bomac cells Bovine macrophage CpG DNA PAMPs poly(I:C) RNAseq [DOI] 10.1186/s12864-018-5411-5 PMC 바로가기 [Article Type] Research Article
Impact of Interferon-α Receptor-1 Promoter Polymorphisms on the Transcriptome of the Hepatitis B Virus-Associated Hepatocellular CarcinomaOriginal Research Published on 2018-04-162023-06-03 Journal: Frontiers in Immunology [Category] B형 간염, Fulltext, [키워드] Hepatitis virus B Hepatocellular carcinoma interferon-α receptor interferon-α receptor type-1 promoter polymorphism RNAseq the Cancer Genome Atlas project Transcriptome [DOI] 10.3389/fimmu.2018.00777 PMC 바로가기 [Article Type] Original Research
Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose마이코박테리아의 세포 외피 스트레스는 트레할로스에 대한 반응으로 새로운 신호 전달 ATPase IniR에 의해 조절됩니다Research Article Published on 2017-12-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Activation activator Affect assembly ATPase Author BAC bacterial cell biogenesis cascade Cell cell envelope cell wall complex compounds damaged defect domain domains drug ethambutol experiment explain exposure to family Gram-negative bacteria homologue identify include induce inducer integrity involved isoniazid latter gene Lipid lipids locus mechanism Mutagenesis mutant mutants mutations mycobacteria mycobacterial Mycobacterium operon overexpression pathway promoter PROTECT regulated Regulation regulator Regulatory regulatory gene respond RNAseq shown signal Signal transduction Signaling Stress stress response sugar sugars the cell transcriptional regulator transposon trehalose Tuberculosis understanding unique [DOI] 10.1371/journal.pgen.1007131 PMC 바로가기 [Article Type] Research Article
Infection with MERS-CoV Causes Lethal Pneumonia in the Common MarmosetResearch Article Published on 2014-08-212022-10-29 Journal: PLoS Pathogens [Category] Coronavirus, MERS, [키워드] addition Analysis animal model cause common Comorbidities comparable complicate demonstrated different time point Dipeptidyl peptidase 4 disease Disease model Efficacy evaluate expression Extensive humans immune inflammatory pathways Interaction intranasal lack lesion lethal lung marmoset marmoset model MERS-CoV MERS-CoV infection Middle East Mild modeling moderate disease MOST ocular Pathogenesis post inoculation potential therapeutic agent predicted Protein receptor required respiratory syndrome coronavirus rhesus RNAseq robust severe disease severe pneumonia severity spike glycoprotein the disease translated treated treatment strategy Vaccine Viral load virus entry was tested while [DOI] 10.1371/journal.ppat.1004250 PMC 바로가기 [Article Type] Research Article