Development and External Validation of a Machine Learning Tool to Rule Out COVID-19 Among Adults in the Emergency Department Using Routine Blood Tests: A Large, Multicenter, Real-World Study일상적인 혈액 검사를 사용하여 응급실의 성인에서 COVID-19를 배제하기 위한 기계 학습 도구의 개발 및 외부 검증: 대규모, 다기관, 실제 연구Multicenter Study Published on 2020-12-022022-09-12 Journal: Journal of Medical Internet Research [Category] MERS, SARS, 진단, [키워드] 95% CI accelerate Accuracy artificial intelligence AUROC Chain Reaction characteristic Clinical data collected Conventional COVID 19 COVID-19 Cutoff data set decile demonstrated Department develop development Diagnosis diagnosis of COVID-19 electronic medical records Emergency emergency department excluded External external validation Frame hospital hospitals Laboratory laboratory data Laboratory results Laboratory test machine machine learning male median age Model multicenter negative control negative controls Negative predictive value NPV objective outcome pandemic Patient patients PCR PCR-based testing PCR-confirmed polymerase chain polymerase chain reaction predicted Predictive value Prevalence receiver operating characteristic Result reverse transcription reverse transcription polymerase chain reaction risk routine routine blood test routine blood tests RT-PCR rule SARS-CoV-2 SARS-CoV-2 virus score cutoff selective sensitivity specificity Testing Time frame validation [DOI] 10.2196/24048 PMC 바로가기 [Article Type] Multicenter Study
Evolution of Transmissible Gastroenteritis Virus (TGEV): A Codon Usage PerspectiveArticle Published on 2020-10-242022-10-29 Journal: International Journal of Molecular Sciences [Category] Coronavirus, [키워드] adaptive addition analysis Analysis Bayesian inference CAI coding sequence codon codon adaptation index codon usage Codon usage bias comprehensive analysis contribute coronavirus CpG current diarrhea dinucleotide dominant driving effective Evolution Genome Genotype high mortality indicated likelihood moderate Mutation mutation pressure natural selection nucleotide nucleotides parity phylogenetic analysis Phylogeny principal component analysis rule selection pressure similarity subtype suggested synonymous TGEV transmissible gastroenteritis virus Usage was performed [DOI] 10.3390/ijms21217898 PMC 바로가기 [Article Type] Article
Is It High Time to Increase Elite Soccer Substitutions Permanently?Article Published on 2020-09-252022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] change collected comparison coronavirus coronavirus disease COVID-19 determine dimension eight Elite evaluate example fatigue FIVE Football incidence increase Injury mitigate occur pandemic performed physical physical demand Prophylaxis rule Rules Simulation Sports Medicine Substitution substitutions time understanding [DOI] 10.3390/ijerph17197008 PMC 바로가기 [Article Type] Article
Optimization Rules for SARS-CoV-2 M pro Antivirals: Ensemble Docking and Exploration of the Coronavirus Protease Active SiteArticle Published on 2020-08-262022-10-28 Journal: Viruses [Category] COVID-19, MERS, [키워드] 6LU7 accession number aliphatic antivirals assist average Bank binding binding affinity Bioactivity Compound compounds Coronaviruses COVID-19 crystal structures current described determine develop docked docking docking score drug candidates effort Epidemic exploration feature greater Health hydrophobic increase in inhibitor inhibitor design Interaction M pro magnitude molecular molecular docking molecular docking studies molecular dynamics molecular interactions optimization pandemic Pandemics PDB preference produced producing protease Protease inhibitor Research residues resulting rule SARS-CoV-2 SARS-CoV-2 Mpro SARS-CoV-2 main protease Site targets the SARS-CoV-2 therapeutic utility Vaccine viral infection [DOI] 10.3390/v12090942 PMC 바로가기 [Article Type] Article
Lessons from the Mainland of China’s Epidemic Experience in the First Phase about the Growth Rules of Infected and Recovered Cases of COVID-19 WorldwideArticle Published on 2020-08-182022-10-30 Journal: International Journal of Disaster Risk Science [Category] COVID-19, [키워드] applied China Chinese coronavirus country COVID-19 COVID-2019 death rate Ebola virus Effectiveness Epidemic Epidemics Epidemiological properties Evidence experience explained growth infected case lesson linear relationship Logistic Logistic model mainland measure negative correlation novel coronavirus disease outbreak pandemic phase positive correlation predicted question R 2 recovered Region rule the timing [DOI] 10.1007/s13753-020-00294-7 PMC 바로가기 [Article Type] Article
Rules and guidelines for distancing in daily life to control coronavirus disease 2019 in Korea: 3rd version, announced on July 3, 2020Educational/Faculty Development Material Published on 2020-07-132022-10-30 Journal: Journal of educational evaluation for health professions [Category] COVID-19, MERS, [키워드] activities collective Community coronavirus disease cough COVID-19 COVID-19 pandemic Disinfection facilitate Government Health individual Infection prevention introduced Korean measure number of infected organization Pandemics physically prevalence of COVID-19 provide reported Republic of Korea rule severe acute respiratory syndrome coronavirus 2 sneeze social interaction spread of COVID-19 Support supported [DOI] 10.3352/jeehp.2020.17.20 PMC 바로가기 [Article Type] Educational/Faculty Development Material