Extracorporeal membrane oxygenation and COVID-19: The causes of failureCase Reports Published on 2020-10-012023-07-06 Journal: Journal of cardiac surgery [Category] SARS, [키워드] acute respiratory distress syndrome extracorporeal membrane oxygenation hypercoagulability. SARS Coronavirus SARS-CoV infection [DOI] 10.1111/jocs.14867 PMC 바로가기 [Article Type] Case Reports
Renin Angiotensin System, COVID-19 and Male Fertility: Any Risk for Conceiving?Review Published on 2020-09-282022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] ACE2 ACE2 expression ACE2 receptor acute respiratory syndrome addition Affect Analysis angiotensin angiotensin-converting enzyme 2 bioinformatics concern concerning connection consequence coronavirus COVID-19 expected expression host cells in vitro Inflammatory Intervention investigated knowledge Laboratory lesion male male fertility management pathway Patient patients pharmacological Prevent RAS receptor Renin reproductive required risk SARS-CoV infection SARS-CoV-2 SARS-COV-2 infection severity System target tissue tissues [DOI] 10.3390/microorganisms8101492 PMC 바로가기 [Article Type] Review
Anti-SARS-CoV Natural Products With the Potential to Inhibit SARS-CoV-2 (COVID-19)Pharmacology Published on 2020-09-252022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] coronavirus acute respiratory syndrome against SARS-CoV colds Compound computational method conducted coronavirus Coronavirus-2 coughs COVID-19 drug drugs Ethnomedicine Fever greater HCoV highlight host receptor Human in vitro in vivo Infection Influenza information inhibit mitigate natural natural products novel drug candidates Numerous pandemic plant Potential product Proteases required respiratory viral infection RNA genome SARS-CoV SARS-CoV infection SARS-CoV-2 screened Secondary Metabolite secondary metabolites shown similarity Symptom target the disease viral infections [DOI] 10.3389/fphar.2020.561334 PMC 바로가기 [Article Type] Pharmacology
Immune cell puzzle COVID-19: how do SARS-CoV infections contribute to psychiatric diseases?Editorial Published on 2020-08-042022-10-31 Journal: European archives of psychiatry and clinical neuro [Category] COVID-19, SARS, [키워드] Cell contribute Psychiatric SARS-CoV infection [DOI] 10.1007/s00406-020-01179-y PMC 바로가기 [Article Type] Editorial
Expansion of Single Cell Transcriptomics Data of SARS-CoV Infection in Human Bronchial Epithelial Cells to COVID-19Research Published on 2020-07-232022-10-27 Journal: Biological Procedures Online [Category] COVID-19, [키워드] Activation acute respiratory syndrome addition Analysis applied association Atla B- and T-cells bronchial bronchial epithelial cell bronchial epithelial cells cell line coronavirus coronavirus disease COVID-19 COVID-19 patients Critical Cytokine storm database dendritic cells downregulated downregulated gene expand expansion expected functional gene Gene ontology Golgi highest homolog Human Hyperactivation immune system immunological Immunological regulations infected cell Ontology overlap pathway phosphatase platform Proinflammatory cytokine proinflammatory cytokines Protein PTEN Reactome pathways Regulation Result SARS-CoV SARS-CoV infection SARS-CoV-2 secretion Severe acute respiratory syndrome shown signaling pathways similarity Single Cell Spread System biology to define Transcriptome transcriptomics Transport Vaccine Wuhan, China [DOI] 10.1186/s12575-020-00127-3 PMC 바로가기 [Article Type] Research
SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls Research Published on 2020-07-152022-10-05 Journal: Nature [Category] SARS, 치료기술, 치료법, [키워드] acute respiratory syndrome Affect Betacoronavirus CD4 CD8 T cell Clinical severity conserved Contact coronavirus coronavirus disease Coronaviruses COVID-19 COVID-19 pandemic cross-reactivity Donor exhibited General population homology Human Immunity immunodominance individual individuals induce Infection long-lasting management memory T cell N protein Nsp7 nucleocapsid ORF1 outbreak pathogen pathogenesis of SARS-CoV-2 Patient Protein reactive recognize Region robust SARS-CoV SARS-CoV infection SARS-CoV-2 SARS-CoV-2-specific T cell subsequent susceptibility T cell T cell response the disease the N protein understanding uninfected uninfected control [DOI] 10.1038/s41586-020-2550-z [Article Type] Research
Neutrophils, Crucial, or Harmful Immune Cells Involved in Coronavirus Infection: A Bioinformatics Study코로나바이러스 감염과 관련된 호중구, 결정적 또는 유해한 면역 세포: 생물정보학 연구Genetics Published on 2020-06-092022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] activated biological processe analyzed ARG1 arginase Arginase inhibitor Arginase inhibitors basophilia bioinformatics BPI CAMP cause caused Cell co-expression network analysis Coronaviridae Coronaviridae family coronavirus disease Coronavirus disease 2019 CoV infection COVID-19 COVID-19 patients CXCL1 death deconvolution analysis DEFA4 demonstrated disease ELANE evaluated followed by GEO2R GEO2R analysis global health GO analysis GSE1739 GSE1739 microarray dataset Health infect inhibitor inhibitors involved Lower respiratory tract lymphopenia molecular mechanism most activated biological processes network analysis neutrophil neutrophil activation neutrophil degranulation neutrophilia new virus ORM2 pandemic PBMC Pneumonia predicted preserved respiratory respiratory tract respiratory tract cells RETN SARS infection SARS-CoV SARS-CoV infection SARS-CoV-2 SARS-positive patients SARS-positive PBMC serpin serpins severe acute respiratory tract syndrome significantly similarity suggested survival syndrome the Coronaviridae the disease turquoise module WGCNA [DOI] 10.3389/fgene.2020.00641 PMC 바로가기 [Article Type] Genetics
Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK SignalingPharmacology Published on 2020-06-032022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] activated acute respiratory distress acute respiratory syndrome benefit cardiovascular cardiovascular burden cardiovascular disease cardiovascular risk caused China contagious coronavirus CoV COVID-19 COVID-19 patients CVD de novo demonstrated drug globe healthy individuals higher risk indicated induce Infectious disease insight MAPK MAPK signaling molecular morbidity new virus Novel coronavirus observation offer outbreak outcome pandemic Pathogenesis pathway Patient predisposition progression RAAS respiratory manifestation role SARS-CoV SARS-CoV infection SARS-CoV-2 SARS-COV-2 infection sequence similarity severe COVID-19 signaling pathways Spread syndrome utility Vascular damage Viral pneumonia Wuhan [DOI] 10.3389/fphar.2020.00836 PMC 바로가기 [Article Type] Pharmacology
Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate modelReport Published on 2020-05-292022-10-28 Journal: Science (New York, N.y.) [Category] COVID-19, MERS, SARS, [키워드] absence acute respiratory syndrome animal model bronchiolar cause ciliated epithelial cell Clinical sign Comparative coronavirus coronavirus disease Coronaviruses COVID-19 cynomolgus macaque Diffuse alveolar damage disease drug treatment Effectiveness extreme foci Human human coronavirus humans Infection Influenza inoculated intestinal tract Isolation Like lung lesion Lung pathology macaque macaques MERS MERS-CoV infection Middle East nasal nasal mucosa nose and throat Older pandemic coronavirus Pathogenesis pathogenesis of COVID-19 pathology Patient peaked pneumocyte provide SARS-CoV SARS-CoV infection SARS-CoV infections SARS-CoV-2 SARS-COV-2 infection Science severe symptom Symptoms syndrome Therapeutic strategies type I type II pneumocytes upper respiratory tracts Vaccine virus [DOI] 10.1126/science.abb7314 PMC 바로가기 [Article Type] Report
ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19Research Paper Published on 2020-04-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] ACE2 ACE2 expression addition Analysis analyzed B cell carcinoma Cell change correlated correlation COVID-19 COVID-19 patient database dendritic cell elevated Endometrial Carcinoma enzyme expression expression level Immune cell immune infiltration in vitro in vivo investigated Kaplan-Meier Macrophage macrophages marker Methylation neutrophil Neutrophils Papillary performed positively correlated Prognosis prognostic biomarker promoter reduced renal SARS-CoV infection SARS-CoV-2 SARS-COV-2 infection significantly subgroup survival susceptible tissue was tested [DOI] 10.18632/aging.103100 PMC 바로가기 [Article Type] Research Paper