Vitamin C and COVID-19 treatment: A systematic review and meta-analysis of randomized controlled trials비타민 C와 코로나19 치료: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-11-012022-09-11 Journal: Diabetes & metabolic syndrome [Category] 임상, 치료법, [키워드] 95% CI administration Analysis Ascorbate ascorbic acid benefit carried control group coronavirus coronavirus disease COVID COVID 19 COVID penumonia COVID-19 disease dose hospital ICU Invasive mechanical ventilation l-ascorbate. Meta-analysis oral Patient Randomized controlled trial Randomized controlled trials Ratio RCT reduce mortality risk ratio route SARS-CoV-2 severity severity of illness SMD systematic review Total Treatment Viral illness viral illnesses Vitamin Vitamin C [DOI] 10.1016/j.dsx.2021.102324 PMC 바로가기 [Article Type] Meta-Analysis
Serum CK-MB, COVID-19 severity and mortality: An updated systematic review and meta-analysis with meta-regression혈청 CK-MB, COVID-19 중증도 및 사망률: 메타 회귀가 있는 업데이트된 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-09-012022-09-11 Journal: Advances in medical sciences [Category] SARS, 바이오마커, [키워드] 95% CI 95%CI Above Analysis aspartate Aspartate aminotransferase Biomarker Blood blood count Brain brain natriuretic peptide CK-MB Concentration conducted COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity creatine creatine kinase Creatine kinase-MB Creatine kinase-MB values Above the normal range D-dimer direction disease severity effect size Egger estimates heterogeneity Lactate lactate dehydrogenase magnitude Meta-analysis meta-regression Mortality myocardial injury Myoglobin non-survivor normal range Patient peptide performed publication bias registration number reported risk stratification searched sensitivity analysis severe disease severity significantly significantly higher SMD standardized mean difference study heterogeneity survivor systematic review t-test T-tests troponin Web of Science [DOI] 10.1016/j.advms.2021.07.001 PMC 바로가기 [Article Type] Meta-Analysis
Cardiac biomarkers and COVID-19: A systematic review and meta-analysis심장 바이오 마커 및 Covid-19 : 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-09-012022-08-31 Journal: Journal of infection and public health [Category] 바이오마커, [키워드] 95% CI 95% confidence interval applied Biomarker cardiac Cardiac biomarkers cardiac troponin Cardiac troponin I cardiac troponin T COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients COVID-19 severity creatine creatine kinase Creatine kinase-MB disease disease mortality disease severity evaluate exhibited Google Scholar Meta-analysis Mortality Myoglobin Patient performed reduce Serum level severity SMD standardized mean difference systematic review Treatment troponin I troponin T was used Web of Science [DOI] 10.1016/j.jiph.2021.07.016 PMC 바로가기 [Article Type] Meta-Analysis
Cardiac biomarkers, cardiac injury, and comorbidities associated with severe illness and mortality in coronavirus disease 2019 (COVID‐19): A systematic review and meta‐analysis코로나바이러스 2019(COVID-19)의 중증 질환 및 사망률과 관련된 심장 바이오마커, 심장 손상 및 동반 질환: 체계적인 검토 및 메타 분석Review Published on 2021-08-182022-09-10 Journal: Immunity, Inflammation and Disease [Category] MERS, SARS, 바이오마커, [키워드] 95% CI Acute cardiac injury acute myocardial injury Biomarker Biomarkers cardiac Cardiac biomarkers cardiac injury cardiovascular disease certainty Clinical research clinical trial clinical trials CNKI Cochrane Library Comorbidities Comorbidity coronavirus disease correlation COVID‐19 COVID‐19 patients COVID‐19 creatine creatine kinase Critical event Evidence except for groups help hypertension IMPROVE Injury Laboratory laboratory parameter Laboratory parameters Lactate lactate dehydrogenase LDH mean difference measure medRxiv meta‐analysis Mortality MOST myocardial injury Myoglobin no difference NT‐proBNP Odds ratio outcome outcome measures Patient patients peptide pool Relative risk Research Result risk SARS‐CoV‐2 sensitivity Serum level severe group severity SinoMed SMD systematic review systemically TnI total sample size Treatment troponin I VIP was performed was related Web of Science [DOI] 10.1002/iid3.471 PMC 바로가기 [Article Type] Review
Cholesterol and Triglyceride Concentrations, COVID-19 Severity, and Mortality: A Systematic Review and Meta-Analysis With Meta-RegressionPublic Health Published on 2021-08-182022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] 95% CI age alteration Aspartate aminotransferase association cholesterol Combination Concentration concentrations conducted coronavirus disease COVID-19 COVID-19 patient COVID-19 severity Demographic variables disease disease severity effect size Egger Endpoint Evidence fraction HDL heterogeneity hospitalized patient hypertension Lipid Meta-analysis meta-regression Mortality non-survivor not affected Patient review risk stratification searched sensitivity analysis severe disease severity significantly significantly lower SMD standardized mean difference survival survivor systematic review t -test Triglyceride triglycerides turn Web of Science with COVID-19 [DOI] 10.3389/fpubh.2021.705916 PMC 바로가기 [Article Type] Public Health
Associations of immunological features with COVID-19 severity: a systematic review and meta-analysisResearch Article Published on 2021-08-032022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, SARS, [키워드] 95%CI association B cell CD3 CD4 CD8 Cell chemokine chemokines Cochrane Library conducted COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokines deaths disease severity effective feature GM-CSF help IFN-γ IL-10 IL-2 IL-4 IL-5 IL-6 Immune cell immune cells immunological IP-10 MCP-1 mean difference measurement Meta-analysis mild case mild cases NK cell NK cells no significant difference RANTES Result Severe case severity significantly higher significantly lower SMD Spread supplementary material systematic review T cell TNF-α Treg Web of Science with COVID-19 [DOI] 10.1186/s12879-021-06457-1 PMC 바로가기 [Article Type] Research Article
Insulin Treatment May Increase Adverse Outcomes in Patients With COVID-19 and Diabetes: A Systematic Review and Meta-AnalysisEndocrinology Published on 2021-07-222022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, [키워드] 95% CI 95% CIs 95% confidence interval Admission Adverse adverse effect adverse outcome adverse outcomes articles association calculated CIs Cochrane Library Complication complications concerning conducted coronavirus disease COVID-19 COVID-19 complication diabete diabetes Egger’s test funnel plots Hospitalization identify In-hospital incidence increase increased mortality increased risk insulin Insulin therapy insulin treatment mechanism Meta-analysis Mortality no significant difference objective Odds ratio Patient patients with COVID-19 Result review significantly SMD standardized mean difference Treatment Web of Science were used [DOI] 10.3389/fendo.2021.696087 PMC 바로가기 [Article Type] Endocrinology
Physical relaxation for occupational stress in healthcare workers: A systematic review and network meta‐analysis of randomized controlled trials의료 종사자의 직업 스트레스에 대한 물리적 이완 : 무작위 통제 시험의 체계적인 검토 및 네트워크 메타 분석Meta-Analysis Published on 2021-07-072022-08-31 Journal: Journal of Occupational Health [Category] meta-analysis, 비임상, 임상, [키워드] 95% CI adverse effect adverse effects baseline best breath Burnout conducted Control controls convenience COVID‐19 database determine Effect effective employer Health health problem healthcare healthcare worker Healthcare workers help massage therapy mean difference measure mental health muscle relaxation network objective occupational health occupational medicine offer online delivery physical physical and mental health progressive muscle relaxation Randomized controlled trial Randomized controlled trials reduce reduced Relaxation representing Result searched SMD Stress subject systematic review therapy Trial was performed wellness programs work yoga [DOI] 10.1002/1348-9585.12243 PMC 바로가기 [Article Type] Meta-Analysis
Electrostatic Interactions Explain the Higher Binding Affinity of the CR3022 Antibody for SARS-CoV-2 than the 4A8 Antibody정전기 상호작용은 4A8 항체보다 SARS-CoV-2에 대한 CR3022 항체의 더 높은 결합 친화도를 설명합니다Article Published on 2021-07-062022-09-12 Journal: The journal of physical chemistry. B [Category] SARS, 진단, [키워드] affinity Amino acid amino acids antibody approach atomic level bind binding affinity candidate coarse-grained simulation coarse-grained simulations complexes Contact contact with COVID-19 therapy CR3022 domain effective electrostatic interaction electrostatic interactions epitope experiments explain higher affinity Interaction mechanism molecular molecular dynamics monoclonal antibodies monoclonal antibody N-terminal domain NTD RBD reveal SARS-CoV-2 SARS-CoV-2 RBD SMD the binding affinity the SARS-CoV-2 therapy treat virus [DOI] 10.1021/acs.jpcb.1c03639 PMC 바로가기 [Article Type] Article
Direct Measurement of B Lymphocyte Gene Expression Biomarkers in Peripheral Blood Transcriptomics Enables Early Prediction of Vaccine SeroconversionArticle Published on 2021-06-252022-10-31 Journal: Genes [Category] COVID-19, [키워드] 95% CI applied approach AUC B cell B lymphocyte B lymphocytes Biomarker blood transcriptome Cell clinical setting collected correlated COVID-19 COVID-19 vaccines datasets determine develop Direct expressed expression FCRLA Gene Expression gene expression dataset Genes greater immunology Influenza leukocyte log measurement mononuclear cells pathway PBMC peripheral Peripheral blood Precision predict predicted prediction Predictive proportion purified reference gene Responder sensitivity Seroconversion SMD subpopulation subpopulations target gene TNFRSF13C TNFRSF17 transcript transcript abundance Transcriptome Trial TXNDC5 vaccination was used [DOI] 10.3390/genes12070971 PMC 바로가기 [Article Type] Article