solid tumors – Page 4 – Communicable Diseases Research

Vaccination Against Diphtheria and Tetanus as a Way to Activate Adaptive Immunity in Children with Solid Tumors

고형 종양이 있는 어린이의 적응 면역을 활성화하는 방법으로 디프테리아 및 파상풍 예방 접종

Original Research

Published on 2021-07-082024-07-28
Journal: Frontiers in immunology [Category] 파상풍,

A retrospective evaluation of the value of COVID-19 screening and testing in patients with cancer: Aiming at a moving target

암환자에서 코로나19 검진과 검사의 가치에 대한 후향적 평가: 움직이는 표적을 겨냥

Article

Published on 2021-07-012022-09-11
Journal: Journal of infection and public health [Category] SARS, 치료기술, 치료제,

[키워드] Acute respiratory infection acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Analysis approval ARI asymptomatic patient asymptomatic patients average calculated Cancer cancer patient Cancer patients Care Chain Reaction Chemotherapy city Community Coronavirus-2 correlated COVID-19 COVID-19 infection Critical Department diagnostic emergency department female gold gold standard Hospitalization Infection institutional review board King Laboratory testing median age Nasopharyngeal and throat National Negative predictive value NPV oncology oncology patient Patient Patient care patients Patients with cancer PCR PCR test PCR tests polymerase chain polymerase chain reaction positive positive PCR PPV Prevalence prevalence of COVID-19 receiving respiratory infection retrospective risk RT-PCR SARS-CoV-2 screened Screening sensitivity Sensitivity and specificity Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus solid tumors specificity study period tested Testing Treatment tumors underlying disease was done was obtained was performed with infection yield
[DOI] 10.1016/j.jiph.2021.05.005 PMC 바로가기 [Article Type] Article

Preinfection laboratory parameters may predict COVID‐19 severity in tumor patients

사전 감염 실험실 파라미터는 종양 환자의 Covid -19 중증도를 예측할 수 있습니다.

Multicenter Study

Published on 2021-06-132022-08-31
Journal: Cancer Medicine [Category] MERS, SARS, 바이오마커,

[키워드] absolute neutrophil count association Asymptomatic Biomarkers Cancer clinical Cohort coronavirus correlated Course COVID‐19 COVID‐19 death defined diagnosed died disease early stage Hematological malignancies Hematological malignancy heterogeneous group identify identifying individual Infection information laboratory parameter Laboratory parameters leads median Mild mild to moderate moderate multivariable analysis neoplasm Neoplasms neutrophil Neutrophils outcome parameter Patient Patients with cancer predict registry Result risk risk factor Risk factors SARS‐CoV‐2 infection SARS‐CoV‐2 severity significantly solid tumor solid tumors subgroups susceptible the disease the strongest the WHO Treatment Tumor tumor registry tumors virus was collected
[DOI] 10.1002/cam4.4023 PMC 바로가기 [Article Type] Multicenter Study

Clinical Presentations and Outcomes of Coronavirus Disease 2019 in Patients With Solid Tumors

Internal Medicine

Published on 2021-06-052022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] 30-day mortality rate affected age Breast cancer Cancer cancer patient Cancer patients Care Chinese clinical clinical presentation Colorectal cancer Comorbidity conducted contracting the virus Coronavirus disease 2019 correlated COVID-19 COVID-19 in patient COVID-19 patient decrease demographic characteristics Diabetic diagnosed Diagnosis Factors General population Health Hospitalized immune individual intensive care Laboratory Leukocytosis lung cancer lymphocytopenia male Mortality mortality rate Older age outcomes pandemic Patient patients patients died polymerase chain populations presentation Prostate Prostate cancer Result Science second set Solid solid tumor solid tumors study population suppresse the median the patient therapy therapy for COVID-19 Tumor university
[DOI] 10.7759/cureus.15452 PMC 바로가기 [Article Type] Internal Medicine

SARS-CoV-2 nosocomial infection: Real-world results of environmental surface testing from a large tertiary cancer center

SARS-CoV-2 병원 감염: 대규모 3차 암 센터에서 환경 표면 테스트의 실제 결과

Article

Published on 2021-06-012022-09-11
Journal: Cancer [Category] SARS, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed Antigen antigen receptor Cancer Cancer center Care Chain Reaction clinics Consensus contaminated surface contaminated surfaces Contamination coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 transmission environmental surface testing equipment evaluated examined Health Organization hematologic hematologic malignancies incidence infection control Laboratory leukemia lymphoma Medical care multitude nosocomial Nosocomial infection oncology Patient Patients with cancer performed positive Positive test potential risk protocol protocols Quality assurance Quality improvement receptor reverse transcriptase reverse transcriptase-polymerase chain reaction Sample SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 viral RNA seeking severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shown solid tumors surface T-cell tested Transmission Viral RNA Viral transmission virus World Health Organization
[DOI] 10.1002/cncr.33453 PMC 바로가기 [Article Type] Article

Evaluation of Seropositivity Following BNT162b2 Messenger RNA Vaccination for SARS-CoV-2 in Patients Undergoing Treatment for Cancer

암 치료를 받는 환자에서 SARS-CoV-2에 대한 BNT162b2 메신저 RNA 백신 접종 후 혈청 양성 평가

Research

Published on 2021-05-282022-09-12
Journal: JAMA Oncology [Category] MERS, SARS, 진단,

[키워드] 95% CI accompanied active treatment age analyses Analysis analyzed anti-S Antibody Response Antibody titer anticancer Beilinson Hospital blood sample Blood samples BNT162b2 BNT162b2 vaccine Cancer center Chemotherapy cohort study comparison Comparisons conducted Control control group COVID-19 COVID-19 disease Davidoff defined develop domain Enrollment evaluate exhibited Factor finding greater healthy control healthy controls high risk higher risk IgG IgG antibodies IgG antibody IgG titer IgG titers immunoassay Immunotherapy Importance intravenous measure median men messenger Messenger RNA multivariable analyses multivariable analysis objective outcome participant Participants Patient Patients with cancer Point Primary outcome prospective cohort study receiving Relevance required Research respond Result RNA SARS-CoV 2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 vaccine SARS-CoV-2 vaccines second dose second messenger secondary Secondary outcomes seropositive Seropositivity serum sample serum samples setting severe COVID-19 disease significantly significantly lower solid tumor solid tumors Study participants Support systemic therapy systemic treatment the patient therapy titers Treatment Tumor tumors vaccination vaccine dose
[DOI] 10.1001/jamaoncol.2021.2155 PMC 바로가기 [Article Type] Research

Vascular Normalization to Improve Treatment of COVID-19: Lessons from Treatment of Cancer

코로나19 치료 개선을 위한 혈관 정상화: 암 치료의 교훈

Article

Published on 2021-05-152022-09-11
Journal: Clinical cancer research : an official journal of [Category] SARS, 임상,

[키워드] abrogate accelerate addition androgen anticancer approach blocker Cancer clinical trial clinical trials contribute Course COVID-19 COVID-19 pandemic Deprivation disease disease course drug dysregulation Effect form hallmark hallmarks help Hypoxemia hypoxemic Hypoxemic respiratory failure identify immune IMPROVE Infection infection with SARS-CoV-2 lesson mechanism morbidity Mortality normalization Other respiratory viruses outcome pathology pathway Patients with cancer patients with COVID-19 poor oxygenation Respiratory failure respiratory viruses solid tumors the disease Therapies therapy thrombotic treat Treatment Tumor tumor cells tumors Vascular vascular abnormalities vascular abnormality vascular effect vasculature viral clearance viral entry
[DOI] 10.1158/1078-0432.CCR-20-4750 PMC 바로가기 [Article Type] Article

Lights and Shadows on Managing Immune Checkpoint Inhibitors in Oncology during the COVID-19 Era

Opinion

Published on 2021-04-152022-10-31
Journal: Cancers [Category] COVID-19,

[키워드] “COVID-19 addressed administration affected anticancer assumption cancer patient Cancer therapy changes in Chemotherapy clinical observation Clinical outcome clinical outcomes clinics Consequences contribute coronavirus disease COVID COVID-19 detrimental Drug safety Effect ENhance evaluate hyper-inflammatory phase Immune checkpoint inhibitor immune response immune system immuno-oncologics immunological immunomodulatory drug Immunotherapy increased risk Infection LIGHT management managing modulating Mortality pandemic Potential question raise raised Safe severe disease course shadow shown simple solid tumors Spread susceptible the patient therapeutic strategy Treatment viral infection worsening
[DOI] 10.3390/cancers13081906 PMC 바로가기 [Article Type] Opinion

mRNA vaccine for cancer immunotherapy

Review

Published on 2021-02-252022-10-30
Journal: Molecular Cancer [Category] COVID-19, Fulltext, MERS,

[키워드] Activation administration anti-tumor immunity antigen-presenting cell APC APCS Appropriate approval Cancer Cancer immunotherapy Cancer vaccine clinical trial drug Express facilitate FDA food Host immune stimulation immunotherapies in vivo inefficient inhibitors investigated Ionizable lipids likelihood Lipid nanoparticle Lipid nanoparticles (LNPs) Modification modifications mRNA mRNA delivery mRNA vaccine mRNAs nucleotide outcome overcome peptides Personalized vaccine platform polymers prevention of COVID-19 provide Safe Self-amplifying mRNA (SAM) solid tumors therapeutic tumor antigen tumor cell tuning vaccination vaccine platform
[DOI] 10.1186/s12943-021-01335-5 PMC 바로가기 [Article Type] Review

Survival and Complications in Pediatric Patients With Cancer and COVID-19: A Meta-Analysis

Oncology

Published on 2021-01-212022-10-31
Journal: Frontiers in Oncology [Category] COVID-19,

[키워드] 95% CI 95% confidence interval acute respiratory syndrome affected all age groups Analysis analyzed calculated Cancer cancer patient Care caused Chi square test childhood cancer children clinical Cochrane Library Complication conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-sectional eligible England Google Scholar hematological Hematological malignancy heterogeneity Hospitalization Hospitalized intensive care intubation JAMA journal Lancet LILACS measure Medicine medRxiv Meta-analysis Mortality Nature New not different Odds ratio outcomes Oxford pandemic Patient patients with COVID-19 pediatric performed random effect registry Result risk risk factor SARS-CoV-2 Science severe acute respiratory syndrome coronavirus 2 solid tumor solid tumors statistical analysis statistically significant difference stratified suffering survival systematic review Tumor university Ventilation ventilatory support was performed WHO
[DOI] 10.3389/fonc.2020.608282 PMC 바로가기 [Article Type] Oncology