Factors for success of awake prone positioning in patients with COVID-19-induced acute hypoxemic respiratory failure: analysis of a randomized controlled trialRandomized Controlled Trial Published on 2022-03-282022-10-04 Journal: Critical Care [Category] 임상, [키워드] Acute hypoxemic respiratory failure AHRF Analysis app assigned Awake prone positioning benefit bpm conducted coronavirus disease COVID-19 decrease Enrollment Factor help HFNC hospital hypoxemic identification number identify IMPROVE increase in interquartile range intubation intubation rate lung multicenter multivariate nasal outcome oxygen Oxygenation Patient patients randomized patients with COVID-19 performed predictor prone positioning Randomized controlled trial randomly assigned patient reduce reduced Registered Respiratory failure respiratory rate risk ROX index significantly standard care survival treated Treatment [DOI] 10.1186/s13054-022-03950-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Role of Telemedicine in Inflammatory Bowel Disease: Systematic Review and Meta-analysis of Randomized Controlled Trials염증성 장 질환에서 원격 진료의 역할: 무작위 대조 시험의 체계적인 검토 및 메타 분석Review Published on 2022-03-242022-09-11 Journal: Journal of Medical Internet Research [Category] 임상, [키워드] 95% CI abstracts Analysis benefit bowel Case report case reports Cochrane Library Controlled Controlled trial COVID-19 Data analysis database Depression disease Disease activity Effectiveness Efficiency groups IBD identify Inflammatory Inflammatory bowel disease Intervention Laboratory life management mean difference medication Meta-analysis mobile phone no significant difference no significant differences outcome pandemic Participants Patient Patient satisfaction Primary outcomes Psychological Quality of life Randomized controlled trial Randomized controlled trials Research review role searched Secondary outcomes Self-efficacy significantly higher significantly lower standard care standard care group Stata subgroup analysis systematic review Telemedicine Web of Science were assessed were excluded were used [DOI] 10.2196/28978 PMC 바로가기 [Article Type] Review
Randomized controlled trial of favipiravir, hydroxychloroquine, and standard care in patients with mild/moderate COVID-19 diseaseRandomized Controlled Trial Published on 2022-03-232022-10-05 Journal: Scientific Reports [Category] SARS, 임상, 치료법, 치료제, [키워드] 95%CI antiviral activity Bahrain biochemical change Characteristics clinical scale Controlled trial COVID-19 COVID-19 disease disease Favipiravir Fever groups Hydroxychloroquine Influenza Mild Moderate COVID-19 Mortality not differ not significant parameter Patient pilot study Platelet Primary outcome proportion Randomized randomized clinical trial Registered Registration Safe SARS-CoV-2 SARS-CoV-2 treatment secondary outcome secondary outcome measure standard care Standard therapy symptomatic patient therapeutic therapy Trial uric acid viral clearance virus West Nile Virus with COVID-19 [DOI] 10.1038/s41598-022-08794-w PMC 바로가기 [Article Type] Randomized Controlled Trial
Efficacy and Safety of SARS-CoV-2 Neutralizing Antibody JS016 in Hospitalized Chinese Patients with COVID-19: a Phase 2/3, Multicenter, Randomized, Open-Label, Controlled Trial입원한 중국인 COVID-19 환자에서 SARS-CoV-2 중화 항체 JS016의 효능 및 안전성: 2/3상, 다기관, 무작위 배정, 공개 표지, 대조 시험Clinical Trial Published on 2022-03-152022-09-12 Journal: Antimicrobial Agents and Chemotherapy [Category] SARS, 임상, 진단, [키워드] 1:1 28-day mortality 95% confidence interval acute respiratory syndrome adverse event adverse events analyzed assigned benefit Chinese Chinese patient Clinical efficacy clinical status control group Controlled Controlled trial coronavirus COVID-19 disease course disease deterioration Efficacy evaluated group Hospital stay Hospitalized hospitalized patient in both group include JS016 moderate monoclonal antibody Most patients multicenter Negative conversion rate Neutralizing Neutralizing antibodies neutralizing antibody occurred Odds ratio Open-label outcome Patient phase phase 2/3 preclinical studies Prevent Primary outcome randomization Randomized Randomly receive recombinant Registered Safety SARS-CoV-2 SARS-CoV-2 neutralizing antibody SARS-CoV-2 nucleic acid secondary severe coronavirus disease severe COVID-19 disease severity single intravenous infusion standard care therapeutic effect therapy ventilator-free day [DOI] 10.1128/AAC.02045-21 PMC 바로가기 [Article Type] Clinical Trial
Adverse effects of remdesivir, hydroxychloroquine and lopinavir/ritonavir when used for COVID-19: systematic review and meta-analysis of randomised trialsCOVID-19에 렘데시비르, 하이드록시클로로퀸 및 로피나비르/리토나비르를 사용할 때의 부작용: 무작위 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-03-022022-09-11 Journal: BMJ Open [Category] SARS, 임상, [키워드] 95% CI Acute kidney injury Adverse adverse effect adverse events approach cardiac toxicity certainty certainty of evidence cognitive conducted COVID-19 database delirium diarrhoea Diseases drug Effect enrolled Evidence Hydroxychloroquine increase Infectious diseases information Intervention Lopinavir Lopinavir/ritonavir management Meta-analysis moderate nausea outcome pairwise meta-analysis patients patients with COVID-19 Placebo Randomised trial randomised trials recommendation Remdesivir risk risk difference Ritonavir searched standard care Support systematic review vomiting [DOI] 10.1136/bmjopen-2020-048502 PMC 바로가기 [Article Type] Meta-Analysis
Prognostic and Predictive Biomarkers in Patients With Coronavirus Disease 2019 Treated With Tocilizumab in a Randomized Controlled Trial무작위 대조 시험에서 토실리주맙으로 치료된 2019 코로나바이러스 질환 환자의 예후 및 예측 바이오마커Clinical Trial Published on 2022-03-012022-09-11 Journal: Critical Care Medicine [Category] MERS, SARS, 바이오마커, 임상, 진단, [키워드] (interleukin-6 additional sensitivity analyses Analysis antibody assigned binomial Biomarker Biomarkers C-reactive protein candidate Clinical outcome clinical outcomes clinical status Controlled coronavirus disease Coronavirus disease 2019 COVACTA D-dimer death dimer double-blind Effect Europe evaluated Exploratory analysis ferritin ferritin level hospital discharge Hospitalized Interaction interleukin interleukin-6 Lactate lactate dehydrogenase Lymphocytes measurement mechanical ventilation modeling Monocytes Mortality multicenter Multiple Neutrophils North America observational study Ordinal Scale outcome Patient patients hospitalized phase 3 trial Placebo placebo-controlled Platelets Pneumonia Predictive Predictive value prognostic randomization Randomized Randomly receiving receptor retrospective seven-category ordinal scale severe coronavirus disease standard care Tocilizumab treatment with tocilizumab Trial were measured [DOI] 10.1097/CCM.0000000000005229 PMC 바로가기 [Article Type] Clinical Trial
Effect of single session receptive music therapy on anxiety and vital parameters in hospitalized Covid-19 patients: a randomized controlled trialArticle Published on 2022-02-242022-10-04 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] Anxiety asked assigned concerning conducted control group COVID-19 patient Depression disorder Effect evaluate feasibility Health care Hospitalized immediate effect IMPROVE Intervention Medical research music therapy oxygen saturation parameter participant Patient patients Psychology question Randomized controlled trial reduce Result Satisfaction Significant significantly significantly higher standard care statistically Stress therapy treatment group vital parameter [DOI] 10.1038/s41598-022-07085-8 PMC 바로가기 [Article Type] Article
Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial캐나다에서 COVID-19로 병원에 입원한 환자의 치료를 위한 Remdesivir: 무작위 대조 시험Randomized Controlled Trial Published on 2022-02-222022-09-11 Journal: CMAJ : Canadian Medical Association journal = jour [Category] COVID19(2023년), SARS, 임상, 치료제, [키워드] 95% CI 95% confidence interval adverse event age Analysis assigned baseline Canada changes in Characteristics clinical outcomes Clinical severity conjunction Consent Controlled trial COVID-19 creatinine Data collection defined demographics dialysis duration of symptom Effect enrolment evaluated event followed by groups Health care health care systems Health Organization health systems hepatic dysfunction hospital Hospital mortality Hospital stay hospitals in-hospital mortality incidence intravenously mechanical ventilation mechanically ventilated Mortality no difference Open-label outcome oxygen Patient patients performed Pragmatic Primary outcome Randomized Randomized controlled trial randomized patient RCT receive receiving Relative risk Remdesivir risk secondary Secondary outcomes severity of symptom Sex significant effect solidarity Solidarity trial standard care Standard deviation Standard of care Standard-of-care Treatment Trial Trial registration ventilator-free day Ventilator-free days with COVID-19 World Health Organization [DOI] 10.1503/cmaj.211698 PMC 바로가기 [Article Type] Randomized Controlled Trial
Telemedicine in Cardiology: Modern Technologies to Improve Cardiovascular Patients’ Outcomes—A Narrative Review심장의 원격 의료: 심혈관 환자의 결과를 개선하기 위한 현대 기술 - 내러티브 검토Review Published on 2022-02-012022-09-10 Journal: Medicina [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] addition approach arrythmia benefit best cardiological Cardiology cardiovascular clinical setting Contact contact with COVID-19 outbreak current Data processing Diagnosis diagnostics direct contact Evidence evidence of example expressed Healthcare professional healthcare professionals Healthcare system Healthcare systems heart failure include instance Ischemia lack less monitoring narrative Patient physical Registration remote review solution standard care subjects technology Telemedicine Treatment [DOI] 10.3390/medicina58020210 PMC 바로가기 [Article Type] Review
Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COVID-19, SARS, MERS or influenza: A systematic review and meta-analysis of randomised trialsCOVID-19, SARS, MER 또는 인플루엔자로 입원 한 환자의 글루코 코르티코이드, 심혈관 합병증 및 사망률의 전신 투여 : 무작위 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-02-012022-09-10 Journal: Pharmacological research [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] 95% CI administration all-cause mortality benefit cardiometabolic cardiovascular complication cardiovascular complications Confidence intervals COVID-19 Dexamethasone Effects estimate Follow-up glucocorticoid Glucocorticoids hospitalised in-hospital mortality Influenza lower mortality Mantel-Haenszel mechanical ventilation MERS Meta-analysis Mortality objective outcomes oxygen Patient patients Placebo random effect randomisation Randomised trial randomised trials receiving reduce reduce mortality reduced reduction renal function reported respiratory Respiratory Support respiratory viral infections Result risk severe COVID-19 significantly standard care Steroids subgroup subgroups systematic review systemic systemic glucocorticoid systemic glucocorticoids Treatment trials Viral was reduced were used with COVID-19 worsening [DOI] 10.1016/j.phrs.2021.106053 PMC 바로가기 [Article Type] Meta-Analysis