Old and New Calcineurin Inhibitors in Lupus NephritisReview Published on 2021-10-212024-09-02 Journal: Journal of Clinical Medicine [Category] 대상포진, [키워드] calcineurin inhibitors cyclosporine lupus nephritis Proteinuria tacrolimus voclosporin [DOI] 10.3390/jcm10214832 PMC 바로가기 [Article Type] Review
Humoral and T-cell responses to SARS-CoV-2 vaccination in patients receiving immunosuppression면역 억제를 받는 환자에서 SARS-CoV-2 백신 접종에 대한 체액 및 T 세포 반응Article Published on 2021-10-012022-09-11 Journal: Annals of the rheumatic diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] antibody Antibody Response assays Autoimmune Autoimmune diseases B-cell B-lymphocytes BNT162b2 BNT162b2 mRNA ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccines Combination COVID-19 detectable Diseases Efficacy Evidence evidence of failure glomerular glomerular diseases healthy individuals immune responses immunogenic immunogenicity Immunological response Immunosuppression immunosuppressive immunosuppressive therapies immunosuppressive therapy impair induce investigated Lymphocytes mounted non-responder participant Patient preserved receiving responders response responses rituximab robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2 vaccine SARS-CoV-2 vaccines Seroconversion seroconvert seroconverted serological serology T-cell ELISpot T-cell Response T-cell responses tacrolimus therapy vaccination Vaccine vaccine dose Vaccines were used [DOI] 10.1136/annrheumdis-2021-220626 PMC 바로가기 [Article Type] Article
Hyperimmune plasma in three immuno-deficient patients affected by non-severe, prolonged COVID-19: a single-center experience비 종교, 연장 된 Covid-19의 영향을받는 3 명의 면역 결핍 환자에서의과 면역 혈장 : 단일 중심 경험Case Reports Published on 2021-07-012022-09-01 Journal: BMC Infectious Diseases [Category] SARS, 진단, [키워드] Administered affected antibody benefit clinical trials convalescent plasma COVID-19 develop disease Ebola Efficacy Evidence female follicular Follicular lymphoma Hyperimmune plasma immunization immunodeficiency Immunosuppressed Immunotherapy infected patients infusion initial lack leukemia lung transplant lymphoma male MERS Neutralizing antibodies Neutralizing titer Non-neutralizing antibodies non-neutralizing antibody Other Viral Diseases passive immunization Patient patients plasma positive reduced reported SARS-CoV2 single-center subjects Support tacrolimus tested therapy treat treated Treatment treatment of COVID-19 Viral diseases [DOI] 10.1186/s12879-021-06321-2 PMC 바로가기 [Article Type] Case Reports
Methylprednisolone Pulses Plus Tacrolimus in Addition to Standard of Care vs. Standard of Care Alone in Patients With Severe COVID-19. A Randomized Controlled TrialMedicine Published on 2021-06-142022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI addition Administered adverse event all-cause mortality assigned clinical combined use conducted control group Controlled COVID-19 COVID-19 patients cumulative dose Efficacy and safety evaluate event experimental group hazard ratio hospitalized patient Identifier IMPROVE Infection Inflammation Inflammatory inhibitors limitations limited sample size Lung injury median Methylprednisolone non-randomized study non-serious adverse Open-label Patient Primary outcome pulse randomization Randomized RCT receiving SARS-CoV-2 secondary outcome Secondary outcomes severe COVID-19 significantly significantly lower single-center SOC stability Stage Standard Standard of care statistically significant subsequent tacrolimus the SARS-CoV-2 therapy Treatment Trial triggered two groups [DOI] 10.3389/fmed.2021.691712 PMC 바로가기 [Article Type] Medicine
Tacrolimus versus cyclophosphamide for patients with idiopathic membranous nephropathy and treated with steroids: a systematic review and meta-analysis of randomized controlled trialsarticle Published on 2021-05-212024-09-02 Journal: Renal failure [Category] 대상포진, [키워드] Cyclophosphamide Idiopathic membranous nephropathy Meta-analysis Steroids tacrolimus [DOI] 10.1080/0886022X.2021.1914655 PMC 바로가기 [Article Type] article
Kidney Transplantation and COVID-19: Two Case Reports신장 이식과 COVID-19: 2건의 사례 보고Case Reports Published on 2021-05-012022-09-11 Journal: Transplantation proceedings [Category] SARS, 치료제, [키워드] Azithromycin Blood level Comorbidities coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 pneumonia decreased mortality diagnosis of COVID-19 died dosage dose Favipiravir glucocorticoid Glucocorticoids hospital Hydroxychloroquine Immunosuppression immunosuppressive immunosuppressive therapy kidney transplant recipient kidney transplant recipients medication Methylprednisolone MMF mycophenolate mycophenolate mofetil oseltamivir Patient Pneumonia Population Prednisone reduction in reflect report risk tacrolimus therapeutic therapy Transplant transplantation treated Treatment treatment regimen treatment with methylprednisolone Trough level was reduced with COVID-19 [DOI] 10.1016/j.transproceed.2020.10.051 PMC 바로가기 [Article Type] Case Reports
Coronavirus Disease 2019 in Kidney Transplant Recipients: Single-Center Experience and Case-Control Study신장 이식 수혜자의 코로나바이러스 질병 2019: 단일 센터 경험 및 사례 통제 연구Article Published on 2021-05-012022-09-11 Journal: Transplantation proceedings [Category] SARS, 치료제, [키워드] age and sex Bacterial infections calcineurin Case fatality rate Case series Clinical course Clinical outcome clinical outcomes comparable Control controls coronavirus disease Coronavirus disease 2019 COVID-19 diagnosed with COVID-19 died drug level exclusion experience fatality Hemodialysis Hospitalized Immunosuppression Infection inhibitor kidney transplant recipients mammalian morbidity morbidity and mortality mTOR no significant difference no significant differences non-transplant patient non-transplant patients outcome pandemic Rapamycin recipient Secondary infection secondary infections single-center Sirolimus tacrolimus Transplant with COVID-19 [DOI] 10.1016/j.transproceed.2021.01.002 PMC 바로가기 [Article Type] Article
Is Kidney Transplantation From a COVID-19-Positive Deceased Donor Safe for the Recipient?COVID-19 양성 사망 기증자의 신장 이식은 수혜자에게 안전한가요?Case Reports Published on 2021-05-012022-09-11 Journal: Transplantation proceedings [Category] SARS, 치료기술, [키워드] Abnormalities abnormality acute respiratory disease acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Ambulatory peritoneal dialysis anti-SARS-CoV-2 IgM antilymphocyte Chain Reaction Chest chest X-ray Cold coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 creatinine Deceased declined Determining dialysis discharged Donor Evidence evidence of febrile had no Hemodialysis Hospital stay IgG Immunosuppression Infection Ischemia kidney kidney damage kidney transplant material Methylprednisolone mycophenolic acid Nasopharyngeal swab no evidence of organ pandemic Patient Peritoneal dialysis polymerase chain polymerase chain reaction positive recipient reverse transcription reverse transcription polymerase chain reaction risk of transmission rRT-PCR SARS-CoV-2 serum serum creatinine severe acute respiratory syndrome Coronavirus significantly surgery Symptom tacrolimus therapy Transmission transplantation Urine urine output were used [DOI] 10.1016/j.transproceed.2021.01.025 PMC 바로가기 [Article Type] Case Reports
Randomized clinical trial to compare the efficacy of ivermectin versus placebo to negativize nasopharyngeal PCR in patients with early COVID-19 in Peru (SAINT-Peru): a structured summary of a study protocol for randomized controlled trial페루의 초기 COVID-19 환자(SAINT-Peru)에서 비인두 PCR을 무효화하기 위해 이버멕틴 대 위약의 효능을 비교하기 위한 무작위 임상 시험(SAINT-Peru): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-092022-09-01 Journal: Trials [Category] MERS, 임상, 진단, [키워드] 1:1 Administered adverse event allergy Amiodarone Anosmia Antiviral attending physician baseline blinded Blinding block childbearing age clarithromycin clinical clinical and laboratory parameters clinical care clinical trial Cobicistat coin conducted control group correlation cough COVID-19 COVID-19 disease COVID-19 patient COVID-19 pneumonia COVID-19 progression criteria Critical current cyclosporine CYP3A4 daily dose death determine determined by diagnosed diagnostic test Diltiazem dissemination dose drug early treatment Efficacy element Eligible patients emergency services enrolled epidemiologist erythromycin evaluate expected Fever follow-up visits generate hospital Hospitalization IgA IgG IgM IIa immune response immunomodulatory in vivo include inclusion criteria Indinavir Infection Informed consent inhibitor Intervention intestinal investigator investigators involved itraconazole Ivermectin ketoconazole laboratory parameter less list lung magnitude medical staff nasopharyngeal nasopharyngeal specimen Nasopharyngeal swab nasopharyngeal swab PCR nasopharyngeal swabs National negative number objective Older outcome oxygen oxygen saturation Parallel Arm participant Patient patients patients with SARS-CoV-2 PCR PCR cycle Peru Pharmacist phase Placebo placebo group placebo-controlled trial Pneumonia positive positive PCR test positive SARS-CoV-2 PCR pregnancy test pregnant women principal investigator progression proportion protocol quinidine randomization list Randomized Randomized controlled trial Randomly Rapid diagnostic test receive recruited reduce Registered Registration Result risk factor Risk factors Ritonavir Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR SARS-CoV-2 RNA SARS-CoV-2 viral load secondary Secondary objectives Seroconversion Seven severe disease severity spironolactone statistician status study population Study protocol supplementary material Symptom symptomatic Symptomatology Symptoms tacrolimus the patient the placebo group the SARS-CoV-2 threshold Treatment treatment group treatment groups treatment initiation Trial Trial registration two group two groups verapamil Viral Viral load virus Warfarin website with COVID-19 women [DOI] 10.1186/s13063-021-05236-2 PMC 바로가기 [Article Type] Letter
Protective Role of Tacrolimus, Deleterious Role of Age and Comorbidities in Liver Transplant Recipients With Covid-19: Results From the ELITA/ELTR Multi-center European StudyMulticenter Study Published on 2021-03-012023-07-13 Journal: Gastroenterology [Category] SARS, [키워드] COVID-19 Liver transplantation outcome tacrolimus [DOI] 10.1053/j.gastro.2020.11.045 PMC 바로가기 [Article Type] Multicenter Study