The impact of vaccine hesitation on the intentions to get COVID-19 vaccines: The use of the health belief model and the theory of planned behavior modelArticle Published on 2022-10-142022-11-16 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, [키워드] Affect affecting conducted covariate COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines Critical cross-sectional Factor Factors group HBM HBM (health belief model) Health Healthcare provider help Intention Intervention MOST Multiple linear regression perceived benefit proportion receive recruited risk Self-efficacy Standard deviation survey platform T-tests the vaccine TPB (theory of planned behavior) vaccinated against COVID-19 vaccination vaccination intention vaccination intentions Vaccine vaccine hesitation. variant were expressed were used [DOI] 10.3389/fpubh.2022.882909 PMC 바로가기
A third dose SARS‑CoV‑2 BNT162b2 mRNA vaccine results in improved immune response in hemodialysis patientsArticle Published on 2022-10-132022-11-15 Journal: Upsala Journal of Medical Sciences [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Abbott anti-S Antigen antivirals BNT162b2 mRNA vaccine Cellular immune response cellular response Chronic kidney disease coronavirus 2 coronavirus disease COVID-19 COVID-19 infection develop dose enrolled evaluated Hemodialysis humoral humoral and cellular immune response. IgG antibody immune response Immunological response ImmunoSpot Infection interquartile range IQR kidney Level median MONITOR monoclonal antibody mRNA pandemic Patient patients positive Protein reactivity respiratory respond robust SARS-CoV-2 SARS-CoV-2 BNT162b2 SARS-CoV-2 bnt162b2 mRNA vaccine T-cell T-cell Response the median the Spike the vaccine uremia vaccine dose Vaccines weaker immune response [DOI] 10.48101/ujms.v127.8959 PMC 바로가기
Comparison of the safety and immunogenicity of the BNT-162b2 vaccine and the ChAdOx1 vaccine for solid organ transplant recipients: a prospective studyArticle Published on 2022-10-132022-11-15 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome administration anti-RBD antibody BNT-162b2 ChAdOx1 vaccine coronavirus coronavirus disease COVID-19 diabetes disease dose doses Effect Efficacy first dose IgG Immunity vaccine Immunoglobulin Infection kidney kidney transplant liver liver transplant Local no difference older patient Organ transplant Patient platform Primary outcome Prospective Study prospectively studied question recipient reduced resulting SARS-CoV-2 SARS-CoV-2 vaccination second dose secondary endpoint seroconversion rate shown side significantly solid organ transplant spread to systemic adverse event the RBD the spike protein the vaccine trials unresponsiveness vaccination Vaccine vaccine doses vaccine platform [DOI] 10.1186/s12879-022-07764-x PMC 바로가기
Type of mRNA COVID-19 vaccine and immunomodulatory treatment influence humoral immunogenicity in patients with inflammatory rheumatic diseasesArticle Published on 2022-10-132022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, [키워드] age anti-SARS-CoV-2 anti-spike-IgG antibody Antibody Response baseline benefit blood sample BNT162b2 Cohort combination therapy COVID-19 COVID-19 vaccination COVID-19 vaccine disease Effect elderly patients eligible examined highest humoral immunogenicity identifying immunomodulatory Immunosuppression increased risk Inflammatory medication monotherapy mRNA mRNA vaccine mRNA-1273 Odds ratio outcomes Patient patients provided recruited reduced response rheumatic disease SARS-CoV-2 SARS-COV-2 infection significantly lower spike IgG Support tested the disease the vaccine Treatment Type vaccination vaccine dose waning immunity [DOI] 10.3389/fimmu.2022.1016927 PMC 바로가기
A comparative study of spike protein of SARS-CoV-2 and its variant Omicron (B.1.1.529) on some immune characteristicsArticle Published on 2022-10-122022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] abrogated activate activated affected antibody Antigen antigenic Antiviral B.1.1.529 binding ability Breakthrough infection comparable complement domain Effects epitope immune characteristics indicated induce inflammatory reaction macrophages molecular Mutation NF-κB nuclear omicron pathogen-associated molecular pathogenicity pro-inflammatory pro-inflammatory cytokine raise receptor S-protein SARS-CoV-2 Spike protein TAK-242 the vaccine Transmissibility trimer variant wild type [DOI] 10.1038/s41598-022-21690-7 PMC 바로가기
Factors influencing the SARS-CoV-2 infection and vaccination induced immune response in rheumatoid arthritisArticle Published on 2022-10-122022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] addition age anti-CD20 therapy anti-S anti-S antibody anti-SARS-CoV-2 antibodies antibody Antibody Response BNT162b2 cell-mediated response Cellular immune response cellular immune responses ChAdOx1 Concentration Corona covariate adjustment COVID-19 COVID-19 vaccine declined dependent on DMARD (disease-modifying antirheumatic drug treatment) domains dose enrolled Factor healthy controls humoral IL-6 inhibitor immune response Infection inhibited investigated IQR magnitude median time mRNA-1273 Patient patients patients treated peptides positive patient reduced respiratory rheumatoid arthritis RNA RNA vaccine SARS-CoV-2 significant effect significantly Specific specific antibodies specific antibody subject T-cell T-cell Response targeted therapy the healthy the interferon the SARS-CoV-2 the vaccine therapy vaccination Vaccine variables was measured were infected [DOI] 10.3389/fimmu.2022.960001 PMC 바로가기
Susceptibility to Resurgent COVID-19 Outbreaks Following Vaccine Rollouts: A Modeling StudyArticle Published on 2022-10-122022-11-16 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] affecting Asymptomatic Characteristics compartmental model conditions contagious country Coverage COVID-19 COVID-19 vaccine COVID-19 vaccines Effect Effectiveness Endemic Epidemics epidemiological expand explain Health help Immunity include initial key factor modeling parameter populations reported resurgent epidemics SARS-CoV-2 SARS-CoV-2 variants Spread susceptibility the disease the SARS-CoV-2 virus the vaccine vaccination vaccination coverage waning immunity [DOI] 10.3390/v14102237 PMC 바로가기
A novel vaccine based on SARS-CoV-2 CD4+ and CD8+ T cell conserved epitopes from variants Alpha to OmicronArticle Published on 2022-10-062022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 100% conserved Analysis Antigen Beta caused CD4 CD4+ CD8 CD8+ T cell clade clades composed confirmed cases conserved COVID-19 cross-protective deaths Delta epitope Epitopes Epsilon Eta Gamma Genome genomes GISAID greater highly antigenic HLA binding hydrophobic IFN-γ IL-10 IL-12 IL-2 IL-6 immune response immune responses immunoinformatics in silico approaches in vivo Lambda long-lasting majority memory Metadata molecular docking Mortality Mutation non-toxic offer omicron ORF ORF1ab ORF8 proteins peptide performed promoted Protein reduced Reinfection SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 variants secretion severity Strains suffered T cell epitope TGF-β Th1 the Spike the vaccine TLR4 Vaccine variant variants virus virus transmission WHO Wuhan [DOI] 10.1038/s41598-022-21207-2 PMC 바로가기
A bivalent SARS-CoV-2 monoclonal antibody combination does not affect the immunogenicity of a vector-based COVID-19 vaccine in macaquesArticle Published on 2022-10-052022-11-15 Journal: Science Translational Medicine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome Adenovirus Administered administration Affect approach cellular immunity coronavirus coronavirus disease COVID-19 COVID-19 vaccine cynomolgus macaques evaluate Human humoral mAb mAbs macaque monoclonal antibody monoclonal antibody combination not affect offer required SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2 variant spike glycoprotein the vaccine Treatment vaccinated individuals vaccination rates Vaccine viral vector-based waning immunity [DOI] 10.1126/scitranslmed.abo6160 PMC 바로가기
A ubiquitous bone marrow reservoir of preexisting SARS-CoV-2-reactive memory CD4+ T lymphocytes in unexposed individualsArticle Published on 2022-10-042022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] analyzed Blood bone Bone marrow CD4 CD4+ CD4+ T lymphocyte CD69 Cell central memory circulating contribute COVID-19 cross-reactive described detectable Efficacy Express human bone marrow immune response Immunity individual investigated long-lasting membrane memory memory CD4+ T lymphocytes memory T cell nucleocapsid protein peptide Peripheral blood phenotype Plasma cells polyfunctional Primary infection provided SARS-CoV-2 systemic immune response T cell T cells the vaccine tissue-resident memory T cells (Trm). vaccination Vaccines [DOI] 10.3389/fimmu.2022.1004656 PMC 바로가기