Psychological Distress in Healthcare Workers between the First and Second COVID-19 Waves: The Role of Personality Traits, Attachment Style, and Metacognitive Functioning as Protective and Vulnerability FactorsArticle Published on 2021-11-112022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] association attachment attachment style Baseline assessment Burnout concerning COVID-19 COVID-19 pandemic determine emotional Factor Factors HCW HCWs healthcare worker Healthcare workers highlight impacted Italian Italy mental health metacognitive functioning moderate outbreak pandemic Personality personality traits Prevalence Protective Psychological Psychological distress questionnaire role Screening second secure stability Stress traits variables vulnerability worker [DOI] 10.3390/ijerph182211843 PMC 바로가기 [Article Type] Article
Interplay between the genetics of personality traits, severe psychiatric disorders and COVID-19 host genetics in the susceptibility to SARS-CoV-2 infectionAcademic Psychiatry Published on 2021-11-072022-10-28 Journal: BJPsych Open [Category] COVID-19, [키워드] acute respiratory syndrome affecting association Cohort complex component contracting the virus coronavirus coronavirus disease correlation COVID-19 COVID-19 susceptibility Evidence examined Extraversion Genetic genetic risk genetic risk factor genetics Genome-wide association study GWAS Health higher risk highlight host genetics individual Interaction linkage Mental disorder Mental Disorders mental health overlapping pandemic Personality personality traits positive psychiatric disorder Psychiatric disorders reflected reported Result risk risk score SARS-CoV-2 SARS-COV-2 infection severe mental disorders severe psychiatric disorder susceptibility traits was used were used with COVID-19 [DOI] 10.1192/bjo.2021.1030 PMC 바로가기 [Article Type] Academic Psychiatry
The SARS-CoV-2 (COVID-19) pandemic in hospital: An insight into environmental surfaces contamination, disinfectants’ efficiency, and estimation of plastic waste production병원의 SARS-CoV-2(COVID-19) 범유행: 환경 표면 오염, 소독제의 효율성 및 플라스틱 폐기물 생산 추정에 대한 통찰력Article Published on 2021-11-012022-09-11 Journal: Environmental research [Category] SARS, 변종, [키워드] alcohol B.1.1.7 caused Cell Characteristics Contamination COVID-19 COVID-19 diagnosis COVID-19 pandemic debatable Disinfection Efficacy Efficiency Environmental surface contamination estimate Ethanol globe high risk hospital hospital ward Hospital wards hypochlorite in viral investigated Lineage Lineage B.1.1.7 management optimization pandemic Patient PCR persistence plastic Plastic residue plastic waste positive positive sample PPE Prevent preventive measure preventive measures reduction residue reveal SARS-CoV-2 Side effect social distancing sodium sodium hypochlorite Spread traits Transmission variant Viral transmission virus virus inactivation VoC VOC 202012/01 VOC lineage B.1.1.7. [DOI] 10.1016/j.envres.2021.111809 PMC 바로가기 [Article Type] Article
Prioritisation of Candidate Genes Underpinning COVID-19 Host Genetic Traits Based on High-Resolution 3D Chromosomal TopologyGenetics Published on 2021-10-252022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] 3D chromosomal architecture applied approach arising association authors Blood Brain candidate capture cells chromosomal COVID-19 COVID-19 pathology COVID-19 susceptibility disease DNA enhancers and promoters experiments expressed Genome-wide association study GWAS GWAS (genome-wide association studies) GWAS meta-analysis GWAS variant High-resolution Inflammatory response Interaction interactions involved lung carcinoma Pathways primary cell type putative target gene Region regions regulate Regulatory regulatory genome severity statistical tissues traits variant viral infection [DOI] 10.3389/fgene.2021.745672 PMC 바로가기 [Article Type] Genetics
Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR유연한 CFDR을 사용하여 GWAS 발견을 향상시키기 위해 임의의 분포에서 보조 데이터 활용Research Article Published on 2021-10-202022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] approach association associations Asthma auxiliary boost can be used category complex complex diseases Conditioning Control correlation covariate detect distribution distributions error rate Evidence evidence of experiments extension false discovery rate FDR functional Genetic genetic association genetic associations Genetic variant genetic variants Genome-wide association studies genomic genomic data genomic region GWAS Human genome identify implementation IMPROVE increase independent Interpretation iterations motivation not significant P -value Pleiotropy power provide Region required resource robust Sample size sensitivity SNP SNPs Statistical power Support Test statistics threshold traits UK Biobank data while [DOI] 10.1371/journal.pgen.1009853 PMC 바로가기 [Article Type] Research Article
Exome sequencing and analysis of 454,787 UK Biobank participantsArticle Published on 2021-10-182022-10-04 Journal: Nature [Category] 바이오마커, 유전자 메커니즘, [키워드] African Analysis Asian association associations Asthma Brain Cancer coding Cohort consequence Deleterious diabete disease European Exome exome sequencing FAM234A GBE1 gene function Genetics research Genome Genome-wide association studies GWAS Human genetics hypertension identify independent individual involved Liver disease loci loss-of-function MAP3K15 Missense participant Phenotypes phenotypic PLD1 protein-coding gene Rare variants Sequencing Sequencing analysis SLC27A3 SLC9A3R2 tested traits UK biobank underlie variant variants Variation [DOI] 10.1038/s41586-021-04103-z PMC 바로가기 [Article Type] Article
Burnout, stress and Type D personality amongst hospital/emergency physiciansOriginal Article Published on 2021-10-152022-10-30 Journal: International archives of occupational and environ [Category] Coronavirus, MERS, SARS, [키워드] association both group Burnout Care Characteristics concerning contribute COVID-19 pandemic cross-sectional Department determinant Emergency emergency physicians Engagement Factor Factors high risk hospital Hospital physicians Improving intensive care inventory involved Leiden measure media Multiple regression analysis Occupational stress offer outcome Perspective physician Physicians Previous studies Quality question questionnaire ranged Result risk factor Satisfaction scale self-report questionnaire Seven Sociodemographic characteristics Stress study population Support surgery traits Type Type D personality was used work [DOI] 10.1007/s00420-021-01766-z PMC 바로가기 [Article Type] Original Article
COVID-19 Pandemic and Personality: Agreeable People Are More Stressed by the Feeling of MissingArticle Published on 2021-10-132022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS, [키워드] addition association changes in conducted consequence COVID-19 COVID-19 pandemic Effect examined feeling FIVE Germany highlight increase in Increased stress individual well-being lockdown longitudinal analysis measure mental health missing outbreak pandemic participant Perceived stress Personality positively correlated Questionnaires resulting Stress tested traits variety [DOI] 10.3390/ijerph182010759 PMC 바로가기 [Article Type] Article
A Chinese host genetic study discovered IFNs and causality of laboratory traits on COVID-19 severityResearch article Published on 2021-10-012022-10-05 Journal: iScience [Category] 변종, 유전자 메커니즘, [키워드] Analysis association Biological sciences caused Chinese cholesterol clinical assessment comprehensive analysis contribute COVID-19 diagnosis COVID-19 pandemic COVID-19 severity current death disease disease severity explain functional gene gene-based analysis Genetic genetic mechanism genetic study genetics GSEA GWAS Host IFN Infection Innate immunity interferon Laboratory mendelian randomization MHC complex MR study Pathways Patient Receptor binding risk factor SARS Coronavirus traits Treatment type I interferon Virology WBC [DOI] 10.1016/j.isci.2021.103186 [Article Type] Research article
COVID-19 patients age, comorbidity profiles and clinical presentation related to the SARS-CoV-2 UK-variant spread in the Southeast of FranceCOVID-19 환자는 프랑스 남동부에있는 SARS-COV-2 UK-Variant와 관련된 연령, 동반 성 프로파일 및 임상 프리젠 테이션Observational Study Published on 2021-09-162022-09-01 Journal: Scientific Reports [Category] SARS, 변종, 임상, 진단, [키워드] Affect age analyzed Characteristics circulating variants Comorbidity COVID-19 patient described emergency department Epidemiology France French Riviera higher risk hospital Hospitalized hospitalized patient hospitalized patients ICU incidence rate increasingly Infectious disease Infectious diseases Modification modifications Nice observational study outcome pandemic Patient patients PCR performed positive sample profile proportion provided representing Respiratory distress syndrome SARS-CoV-2 Sequencing Spread the SARS-CoV-2 traits Transmissibility university university hospital variant viral infection [DOI] 10.1038/s41598-021-95067-7 PMC 바로가기 [Article Type] Observational Study