upregulated
[용어속성] Action
Evidence of Infection of Human Embryonic Stem Cells by SARS-CoV-2
SARS-CoV-2에 의한 인간 배아 줄기 세포 감염의 증거
Article
Published on
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, 치료법, 치료제,
Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, 치료법, 치료제,
[키워드] acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
cell types
coronavirus
described
differentially expressed
dsRNA
embryonic
embryos
enterocytes
Evidence
evidence of
Gut
hepatocytes
hESC
Human
immunofluorescence microscopy
infect
Infection
interferon-stimulated gene
interferon-stimulated genes
ISGs
life cycle
low expression
mechanism
neurons
question
replicate
Replication
replication of SARS-CoV-2
reported
Respiratory system
RNA
S protein
SARS-CoV-2
SARS-CoV-2 receptors
severe acute respiratory syndrome Coronavirus
significantly
STEM
stem cell
supernatant
supernatants
Support
syncytium
threshold
upregulated
variety
Viral RNA
viral titer
viral titers
virion
virus
were infected
[DOI] 10.3389/fcimb.2022.911313 PMC 바로가기 [Article Type] Article
[DOI] 10.3389/fcimb.2022.911313 PMC 바로가기 [Article Type] Article
Cytokine release syndrome-like serum responses after COVID-19 vaccination are frequent and clinically inapparent under cancer immunotherapy
Research
[키워드] 95% CI
absence
Adverse
adverse event
analyzed
Cancer
Cancer immunotherapy
Cancer therapy
clinically
Cohort
cohort study
common
condition
COVID-19 vaccination
COVID-19 vaccines
CRS
CXCL8
cytokine level
Cytokine release syndrome
Cytokines
Diagnosis
eight
elevated
event
Hospitalized
immune
immune response
immune-checkpoint inhibitor
interleukin-6
modulate
observé
occurred
Patient
patients died
receive
response
Serious Adverse Event
serum
serum cytokine
single-center
Symptoms
therapy
Treatment
Tumor
upregulated
vaccination
[DOI] 10.1038/s43018-022-00398-7 [Article Type] Research
[DOI] 10.1038/s43018-022-00398-7 [Article Type] Research
Gene Set Enrichment Analysis Reveals That Fucoidan Induces Type I IFN Pathways in BMDC
유전자 세트 농축 분석을 통해 후코이단이 BMDC에서 I형 IFN 경로를 유도한다는 사실이 밝혀졌습니다
Article
[키워드] activate
Analysis
Antigen presentation
Antiviral
antiviral activity
BMDC
CD40
CD80
cytometric
DEGs
dendritic
dendritic cell
dendritic cells
differentially expressed gene
Differentially expressed genes
differentially expressed genes (DEGs)
driven by
enrichment
enrichment analysis
Flow
Flow cytometric analysis
fucoidan
gene set enrichment analysis
gene set enrichment analysis (GSEA)
greater
GSEA
highlighting
IFN
IFN-stimulated gene
immune cells
Inflammatory response
innate immune
Innate immune cells
IRF
ISG
ISGs
maturation
mechanism
MHCII
NF-κB
NLR
nucleic acid
pathway
Pathways
polysaccharide
potential mechanism
Prevent
PRR
receptor
SARS-CoV-2
Signaling
STAT
STING
sulfated
surface marker
TLR
transcription factors
transcriptional change
transcriptionally
Transcriptome
transcriptome change
treat
Type
type I
Type I IFN
type I interferon
upregulated
viral infections
viruses
[DOI] 10.3390/nu14112242 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/nu14112242 PMC 바로가기 [Article Type] Article
Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study
고형 종양의 영향을 받는 환자에서 발열성 COVID-19의 발병률 및 면역학적 특징: 전향적 코호트 연구
Article
Published on
Journal: Journal of Translational Medicine [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,
Journal: Journal of Translational Medicine [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,
[키워드] affected
Asymptomatic case
Asymptomatic cases
Asymptomatic COVID-19
asymptomatic infection
asymptomatic patient
asymptomatic patients
baseline
Cancer
Cancer center
changes in
chemokine
collected
COVID-19
COVID-19 in patient
COVID-19 pandemic
downregulation
evaluated
feature
First wave
General population
IgM
Immunoglobulin
interleukin 6
Italy
KEGG
mononuclear cell
mononuclear cells
Nasopharyngeal swab
NPs
p-values
pathway
Pathways
Patient
patients
PBMC
PBMCs
performed
Peripheral blood
Peripheral blood mononuclear cells
positive
prospective cohort study
rationale
receptor
recruited
RNA
SARS-CoV-2
SARS-CoV-2 IgM
Sequencing
Seroconversion
seroconversion rate
serology
Signaling
solid cancer
subset
T-cell receptor
tested
Transcriptome
transcriptome sequencing
transcriptomic analysis
transcriptomics
treated
upregulated
Viral
Viral RNA
was performed
[DOI] 10.1186/s12967-022-03429-0 PMC 바로가기 [Article Type] Article
[DOI] 10.1186/s12967-022-03429-0 PMC 바로가기 [Article Type] Article
Identification of Diagnostic Gene Markers and Immune Infiltration in Systemic Lupus
전신성 루푸스에서 진단 유전자 마커 및 면역 침윤의 식별
Article
Published on
Journal: Computational and Mathematical Methods in Medicine [Category] MERS, 바이오마커, 치료기술,
Journal: Computational and Mathematical Methods in Medicine [Category] MERS, 바이오마커, 치료기술,
[키워드] Activation
advancement
Analysis
analyzed
Atypical
autoantibodies
autoantibody
Autoantigens
Autoimmune disease
B cells
bioinformatics
Biomarker
Central nervous system
characteristic
clinical manifestation
clinical manifestations
Clinical practice
coexpressed
coexpression network
complexes
control group
coronavirus
coronavirus disease
correlation
COVID-19
current
DEGs
determine
Diagnosis
diagnostic
differentially expressed gene
Differentially expressed genes
disease
downloaded
downregulated
Endocrine
endocrine system
enrichment analysis
etiology
evaluate
expression data
Factors
fraction
functional
gene expression profile
Genes
Genetic
GEO database
healthy control
healthy controls
help
heterogeneous
highest
hub genes
human body
identification
identify
Immune cell
immune cells
Immune complexes
immune function
Infection
Interaction
joints
KEGG
kidney
leukemia
Lupus
lupus erythematosus
miRNA
multiple organs
Participation
Pathogenesis
pathway
Pathways
Patient
patients
performed
Population
Potential biomarker
potential biomarkers
PPI
PPI network
protein-protein interaction
receiver operating characteristic
recognize
regulatory network
Research
resulting
ribosome
ROC
ROC Curve
RPL19
RPS17
RPS19
RPS7
selected
skin
SLE
SLE patient
SLE patients
Symptom
systemic
systemic lupus erythematosus
T cell
T cells
the disease
the healthy
transcription factor
Treatment
turquoise module
upregulated
variety
virus
was selected
was used
weighted gene coexpression network analysis
WGCNA
whole blood sample
[DOI] 10.1155/2022/3386999 PMC 바로가기 [Article Type] Article
[DOI] 10.1155/2022/3386999 PMC 바로가기 [Article Type] Article
The Impact of Androgen Deprivation Therapy on COVID-19 Illness in Men With Prostate Cancer
전립선암이 있는 남성의 COVID-19 질병에 대한 안드로겐 결핍 요법의 영향
Multicenter Study
[키워드] 95% CI
95% confidence interval
addition
adjusted
Affect
Analysis
androgen
Androgen receptor
androgens
body mass
body mass index
Cell
clinical disease
cohorts
Comorbidity
COVID-19
COVID-19 diagnosis
COVID-19 disease
COVID-19 illness
death
defined
demonstrated
Deprivation
epithelial cells
evaluated
Follow-up
hazard ratio
higher risk
Hospitalization
illness
Impact
Logistic
lower risk
mechanical ventilation
median
median age
multicenter
multicenter study
multivariable
Not demonstrated
Older
outcomes
overall survival
oxygen
Oxygenation
Patient
patients
performed
Prostate cancer
protease
Regression model
regulated
respiratory epithelial cells
retrospective cohort
SARS-CoV-2
SARS-CoV-2 viral
severe COVID-19
severe COVID-19 disease
severe COVID-19 illness
significantly
statistical test
statistically
suggested
supplemental oxygen
survival
therapy
TMPRSS2
Treatment
upregulated
within 6 months
[DOI] 10.1093/jncics/pkac035 PMC 바로가기 [Article Type] Multicenter Study
[DOI] 10.1093/jncics/pkac035 PMC 바로가기 [Article Type] Multicenter Study
Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8
SARS-CoV-2 ORF8에 의한 인터루킨-17A의 바이러스 모방
Article
[키워드] activate
Activation
acute respiratory syndrome
acute respiratory syndrome coronavirus
binding
blood monocyte
blood monocytes
clinical presentation
Clinical presentations
Coagulation
contribute
coronavirus
COVID-19
COVID-19 pathogenesis
cytokine
deleted
disease
disease pathogenesis
dysregulation
fibrosis
Frame
Gene Expression
glycoprotein
Host
IL-17
IL-17A
induce
infected with SARS-CoV-2
Infection
Inflammation
Inflammatory response
Inflammatory responses
interleukin
Mild
milder infection
mimicry
molecular
molecular mechanism
Monocytes
myriad
Open reading frame
ORF8
ORF8 protein
outcome
outcomes
pathway
potential therapeutic target
Protein
receptor
reduced
reveal
robust
SARS-CoV-2
SARS-CoV-2 variants
secreted
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus 2
severe inflammation
Signaling
significantly
Transcriptome
transcriptome analysis
Trigger
triggering
upregulated
variant
viral IL-17.
with mild disease
[DOI] 10.1128/mbio.00402-22 PMC 바로가기 [Article Type] Article
[DOI] 10.1128/mbio.00402-22 PMC 바로가기 [Article Type] Article
Analyzing single cell transcriptome data from severe COVID-19 patients
중증 코로나19 환자의 단세포 전사체 데이터 분석
Article
[키워드] bioinformatics
Cell
cell type
cell types
cellular
Complete
COVID-19
COVID-19 severity
database
detect
disease-associated
enrichment analysis
Gene Expression
Genomics
Health Sciences
identify
immunology
in silico
in vitro
in vivo
marker gene
Molecular biology
protocol
Regulatory
resources
RNAseq
severe COVID-19
severe COVID-19 patient
Single Cell
single-cell
Transcriptome
transcriptomics
upregulated
upregulation
[DOI] 10.1016/j.xpro.2022.101379 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.xpro.2022.101379 PMC 바로가기 [Article Type] Article
Characterization of Altered Gene Expression and Histone Methylation in Peripheral Blood Mononuclear Cells Regulating Inflammation in COVID-19 Patients
COVID-19 환자의 염증을 조절하는 말초 혈액 단핵 세포에서 변경된 유전자 발현 및 히스톤 메틸화의 특성화
Article
[키워드] alteration
Altered
Analysis
approved
arginase
Bone marrow
cause
caused
characterization
chromosome
correlated
COVID-19
COVID-19 disease
COVID-19 patients
COVID-19 treatment
Cytokines
death
Dexamethasone
dysregulated
Epigenetic
expression
expression pattern
expression patterns
expressions
gene expression profile
Gene expression profiles
Genes
healthy control
healthy controls
histone
histone methylation
hospitalized COVID-19 patient
hospitalized COVID-19 patients
IL-1
IL-17
IL-1B
IL-6
indicated
Inflammation
information
inhibitor
investigated
kinase
kinases
long noncoding RNA
majority
mechanisms
member
Methylation
miRNA
pandemic of COVID-19
pathway
Pathway analysis
Pathways
PBMC
PBMCs
peripheral
Potential biomarker
potential biomarkers
proinflammatory cytokines
protein S
provide
receptor
Regulating
Regulation
significantly
target
targets
TEC
TGF-β
therapeutic target
therapeutic targets
treat
Treatment
upregulated
variations
von Willebrand factor
was increased
[DOI] 10.4049/jimmunol.2101099 PMC 바로가기 [Article Type] Article
[DOI] 10.4049/jimmunol.2101099 PMC 바로가기 [Article Type] Article