Severe refractory warm autoimmune haemolytic anaemia after the SARS-CoV-2 Pfizer-BioNTech vaccine (BNT162b2 mRNA) managed with emergency splenectomy and complement inhibition with eculizumabArticle Published on 2022-08-312022-11-15 Journal: BMJ case reports [Category] SARS, 진단, [키워드] 48 hour Autoimmune Bilirubin Blood BNT162b2 mRNA Chest complement Complement pathway Corticosteroid described disease eculizumab fatigue first dose haematology (incl blood transfusion) Haemoglobin highlight inhibitor initiated investigation jaundice lactate dehydrogenase life-threatening liver male over Pfizer-BioNTech SARS-CoV-2 standard treatment the patient the SARS-CoV-2 transplantation Urine Vaccine warm was performed [DOI] 10.1136/bcr-2022-250774 PMC 바로가기
NMR spectroscopy spotlighting immunogenicity induced by COVID-19 vaccination to mitigate future health concernsReview article Published on 2022-08-222022-10-05 Journal: Current Research in Immunology [Category] 바이오마커, 유전자 메커니즘, [키워드] affected Analysis approach BALF biological samples Biomarker Blood breast milk Bronchoalveolar-lavage fluid cerebrospinal fluid chemometrics complex COVID-19 COVID-19 vaccination CSF described detect disease examined example explain Health immunogenicity IMPROVE management metabolome mitigate molecular NMR NMR spectroscopy nuclear Nuclear magnetic resonance spectroscopy PCA Saliva Semen statistical the disease Treatment Urine vaccination Vaccine [DOI] 10.1016/j.crimmu.2022.08.006 [Article Type] Review article
Evaluating and mitigating clinical samples matrix effects on TX-TL cell-free performance Research Published on 2022-08-122022-10-05 Journal: Scientific Reports [Category] 바이오마커, 진단, [키워드] affected arising buffer clinical sample components condition conditions diagnostics Effects evaluate Evaluating glycerol improvement inhibitors inhibitory effect matrix effect medical diagnostics plasma producing Protein reporter RNase inhibitor Saliva serum sfGFP Urine Variability [DOI] 10.1038/s41598-022-17583-4 [Article Type] Research
SARS-CoV-2-positive patients display considerable differences in proteome diversity in urine, nasopharyngeal, gargle solution and bronchoalveolar lavage fluid samplesSARS-CoV-2-양성 환자는 소변, 비인두, 양치액 및 기관지폐포 세척액 샘플에서 단백질체 다양성에 상당한 차이를 나타냅니다.Article Published on 2022-08-082022-09-11 Journal: PLoS ONE [Category] SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 BALF Beijing Bronchoalveolar lavage fluid center chance change characterized Charle China collected coronavirus coronavirus 2 database demonstrated Department downloaded followed by gargle gargle solution Germany Human human body in urine individual infected with SARS-CoV-2 Infection information investigated Mayo Clinic Medicine nasopharyngeal nasopharyngeal sample Nasopharyngeal samples pathology peptide Protein Proteins proteome proteomic proteomics respiratory SARS-CoV-2 SARS-CoV-2 pathogenesis SARS-CoV-2 protein SARS-CoV-2 proteins SARS-CoV-2 proteome SARS-CoV-2 virus SARS-CoV-2 viruses SARS-CoV-2-positive patient SARS-CoV-2-positive patients Science secreted seropositive individuals Severe acute respiratory syndrome significantly more solution status technology the SARS-CoV-2 virus UniProt unique university Urine USA virus viruses was used while [DOI] 10.1371/journal.pone.0271870 PMC 바로가기 [Article Type] Article
Circulating tumour DNA — looking beyond the blood Reviews Published on 2022-08-012022-10-05 Journal: Nature Reviews Clinical Oncology [Category] 바이오마커, 변종, [키워드] Analysis Biomarkers biopsy Blood cerebrospinal fluid circulating Clinical use complementary DNA majority offer over plasma Research review tissue tissue sample unique Urine [DOI] 10.1038/s41571-022-00660-y [Article Type] Reviews
SARS-CoV-2 in infant urine and fecal samples after in utero COVID-19 exposureArticle Published on 2022-08-012022-11-16 Journal: Pediatric Research [Category] SARS, 치료기술, [키워드] acute respiratory syndrome Affect Care coronavirus Coronavirus disease 2019 COVID-19 detect Diagnosis Evidence examined Fecal sample fecal samples Guidance help Infant Infants Infection majority mother Nasopharyngeal swab pandemic patients Pregnancy pregnant women prenatal provide reported Result risk RT-PCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RT-PCR SARS-CoV-2 virus specimens Stage symptomatic disease Transmission transmission of SARS-CoV-2 transmitted Urine virus was collected with COVID-19 women [DOI] 10.1038/s41390-021-01822-x PMC 바로가기
A randomized, controlled, blinded, parallel group, clinical trial to study the role of Ayurcov (AyurCoro3), one day regimen as an adjuvant therapy for COVID-19 disease management, at dedicated Covid Hospital (DCH) in India인도의 코비드 전용 병원(DCH)에서 COVID-19 질병 관리를 위한 보조 요법으로서 Ayurcov(AyurCoro3)의 역할을 연구하기 위한 무작위, 통제, 맹검, 병렬 그룹 임상 시험Randomized Controlled Trial Published on 2022-08-012022-09-11 Journal: Complementary therapies in medicine [Category] SARS, 임상, 치료제, [키워드] adjuvant adverse events alternative medicine alum Antiviral Ayurcov Ayurveda blinded CAM carried Chain Reaction clinical trial complementary Complementary and alternative medicine. control group Controlled trial COVID-19 COVID-19 disease COVID-19 infections Ct values Curcuma Day diagnosed discharge disease dose evaluate Formulation functional Functional status higher risk India ingredient Limited management Mild mild to moderate Mild-to-moderate milk moderate outcome parallel group Patient polymerase chain polymerase chain reaction proportion Randomized real time receiving recruited reduction in regimen resolution of symptom reverse transcriptase Reverse transcriptase polymerase chain reaction Rock Candy rRT-PCR severe COVID-19 disease Severe COVID-19 Infection severe symptoms severity significantly significantly lower significantly more Sita Standard of care Symptom symptom resolution therapeutic effect therapeutic options therapy for COVID-19 transcriptase Treatment Urine [DOI] 10.1016/j.ctim.2022.102824 PMC 바로가기 [Article Type] Randomized Controlled Trial
Development and Validation of a Sensitive and Robust Multiplex Antigen Capture Assay to Quantify Streptococcus pneumoniae Serotype-Specific Capsular Polysaccharides in Urine스트렙토코쿠스 폐렴균 혈청형 특이적 캡슐 다당류를 소변에서 정량화하기 위한 민감하고 강력한 다중 항원 포획 분석법의 개발 및 검증Article Published on 2022-08-012024-07-28 Journal: mSphere [Category] 폐렴구균 감염증, [키워드] community-acquired pneumonia Luminex Multiplex assay pneumococcal disease pneumococcal vaccine Urine vaccine serotypes [DOI] 10.1128/msphere.00114-22 PMC 바로가기
Consensus recommendations for opioid agonist treatment following the introduction of emergency clinical guidelines in Ireland during the COVID-19 pandemic: A national Delphi studyResearch article Published on 2022-08-012022-10-05 Journal: The International Journal on Drug Policy [Category] 치료법, [키워드] Addiction services Care change clinical clinical guideline Clinical guidelines Community Consensus COVID-19 DelPhi Delphi technique develop domains dosage doses drug policy Emergency Final for inclusion Frequency Guidance guideline harm reduction Health identify include introduced involved Ireland lower quartile maintenance phase median methodology National OAT Opioid agonist treatment over pandemic practitioners promote provided psychiatrists reached recommendation recruited Result resulting retained risk Safe Substance use disorder Treatment Urine [DOI] 10.1016/j.drugpo.2022.103768 [Article Type] Research article
Template-Based Assembly of Proteomic Short Reads For De Novo Antibody Sequencing and Repertoire ProfilingDe Novo 항체 시퀀싱 및 레퍼토리 프로파일링을 위한 Proteomic Short Read의 템플릿 기반 어셈블리Review Published on 2022-07-262022-09-11 Journal: Analytical Chemistry [Category] MERS, 유전자 메커니즘, 진단, [키워드] Accuracy antibody antibody repertoire antibody sequence antibody sequences antigens assembly B-cells cDNA sequencing complementary dataset de novo disease Fab feature fluids foundation functional Health homologous homologous antibody hypermutation IgG information light chains Liquid chromatography mass mass spectrometry molecular monoclonal antibody offer Patient patients hospitalized polyclonal polyclonal antibodies polyclonal antibody Profiling proteomic provide Read Recombination repertoire secreted sequence Sequencing sera serological assays serum step Stitch Urine with COVID-19 [DOI] 10.1021/acs.analchem.2c01300 PMC 바로가기 [Article Type] Review