Genomic analysis of early transmissibility assessment of the D614G mutant strain of SARS-CoV-2 in travelers returning to Taiwan from the United States of AmericaMicrobiology Published on 2021-09-022022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] acute respiratory syndrome America Analysis characterized circulation Cluster Comparative Continuous coronavirus COVID-19 D614G D614G mutation determine Direct epidemiological Evolution FIVE Genetic variation Genome genome sequence genomic genomic data GISAID global pandemic highlight imported case Infection isolate isolates mutant network analysis Outbreaks performed Phylogenetic analysis Result returned risk RT-PCR SARS-CoV-2 SARS-CoV-2 variant separated single-nucleotide specimen Surveillance Taiwan the SARS-CoV-2 genome the United State trajectory Transmissibility Transmission Travel USA Variation viral pathogenicity virus virus strain was performed whole-genome sequencing [DOI] 10.7717/peerj.11991 PMC 바로가기 [Article Type] Microbiology
Construction of an autophagy interaction network based on competitive endogenous RNA reveals the key pathways and central genes of SARS-CoV-2 infection in vivo경쟁적 내인성 RNA를 기반으로 한 자가포식 상호작용 네트워크의 구축은 생체 내 SARS-CoV-2 감염의 주요 경로 및 중심 유전자를 밝힙니다Article Published on 2021-09-012022-09-11 Journal: Microbial pathogenesis [Category] SARS, 유전자 메커니즘, [키워드] accompanied addition analyses Analysis autophagy bioinformatics biological processe biological processes Biomarker Biomarkers CCR2 central gene changes in construction Coronavirus infection COVID-19 CXCR4 cytokine receptor Cytokine storm datasets died differentially expressed differentially expressed miRNA differentially expressed miRNAs enriched pathway expression profile Gene Expression Omnibus GEO in vivo Infection Interaction investigated involved knowledge mechanism Messenger RNA microRNA MicroRNAs mild SARS-CoV-2 infection miRNA miRNAs MOST mRNA mRNAs Mutation pandemic Pathogenesis pathogenesis of SARS-CoV-2 pathway Pathway analysis patients with SARS-CoV-2 predict provided raw data receptor reveal RNA SARS-CoV-2 SARS-COV-2 infection severe symptom severe symptoms target the cytokine storm TP53INP2 variety virus strain virus strains [DOI] 10.1016/j.micpath.2021.105051 PMC 바로가기 [Article Type] Article
Investigation of an outbreak of symptomatic SARS-CoV-2 VOC 202012/01-lineage B.1.1.7 infection in healthcare workers, Italy이탈리아 의료 종사자의 증상 SARS-CoV-2 VOC 202012/01-lineage B.1.1.7 감염 발생 조사Article Published on 2021-08-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered Anti-spike Antigen antigen tests B.1.1.7 BNT162b2 BNT162b2 vaccine carried circulation coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Diagnosis doses Efficacy Endotracheal intubation Epidemiological investigation Europe Genetic HCW HCWs healthcare healthcare worker Healthcare workers high risk highlight hospital hospitals IgG IgG anti-Spike antibodies IgG anti-spike antibody Immune Serum immunization implementation IMPROVE Infection investigation involved Italy Mild symptom mild symptoms MINI mRNA vaccine National Neutralizing antibodies outbreak Patient PCR performed Personal protective equipment physician PPE Protein Real-time PCR required respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 lineage SARS-CoV-2 variants SARS-CoV-2 VOC 202012/01-LINEAGE B.1.1.7 second dose Sequencing serological test Serological tests severe acute respiratory syndrome Coronavirus severe COVID-19 subject Surveillance symptom onset symptomatic titre titres transmission of SARS-CoV-2 Vaccine variants virus strain VoC VOC 202012/01 WGS whole-genome sequencing [DOI] 10.1016/j.cmi.2021.05.007 PMC 바로가기 [Article Type] Article
The coSIR model predicts effective strategies to limit the spread of SARS-CoV-2 variants with low severity and high transmissibilityOriginal Paper Published on 2021-07-232022-10-30 Journal: Nonlinear Dynamics [Category] COVID-19, [키워드] addition cause Combination Competitive evolution consequence COVID-19 COVID-19 control strategy COVID-19 pandemic effective effective strategy Epidemic Evolution Fatality rate globe Infectious virus less limit mandatory Mobile mortality rate Multiple outbreak predict protocol quarantine reducing SARS-CoV-2 evolution SARS-CoV-2 variant severe symptom severity SIR model social distancing Spread Strains supplementary material total mortality Transmissibility Transmission unlikely variants of SARS-CoV-2 virus virus strain virus variant wearing mask [DOI] 10.1007/s11071-021-06705-8 PMC 바로가기 [Article Type] Original Paper
Clinical efficacy of Nafamostat Mesylate in combination with Favipiravir for COVID-19 pneumonia treatment review articleReview Published on 2021-07-142022-10-04 Journal: Annals of Medicine and Surgery [Category] 신약개발, 임상, 치료법, 치료제, [키워드] alleviation Anti-inflammatory Antibiotics Anticoagulants Antidote antivirals approach assigned Care category clinical clinical information Clinical outcome collected Combination Compound concerning condition conditions conducted coronavirus COVID COVID-19 COVID-19 infected patient COVID-19 infected patients COVID-19 patient detrimental development drug drugs Effect effective Efficacy enzyme explicit Favipiravir health condition hospital immune implication infected individuals infected patients information inhibit Inpatient intensity involved Laboratory literature review mesylate nafamostat Nafamostat mesylate novel Occurrence outcomes pathologist Patient patients Perspective Pneumonia Prevalence Probability reduce reduction Research research finding researcher responsible RNA polymerase SARS CoV-2 SARS-CoV SARS-CoV-2 SARS-CoV-2 viral Severe respiratory distress therapy Treatment utilised Vaccine viral epidemics viral strain virus strain [DOI] 10.1016/j.amsu.2021.102560 PMC 바로가기 [Article Type] Review
COVID-19: a confirmed case of reinfection in a nurseCOVID-19: 간호사 재감염 확인 사례Case Reports Published on 2021-07-132022-09-12 Journal: BMJ case reports [Category] Coronavirus, SARS, 진단, [키워드] adult intensive care antibody Campania caused COVID-19 Genome sequences IgG immunological immunological products and vaccines Infectious disease Intensive Italy Patient Pneumonia pneumonia (infectious disease) Region Reinfection reported the spike protein Vaccine virus strain [DOI] 10.1136/bcr-2021-244507 PMC 바로가기 [Article Type] Case Reports
BNT162b2-elicited neutralization of B.1.617 and other SARS-CoV-2 variants Research Published on 2021-06-102022-10-05 Journal: Nature [Category] SARS, 변종, 임상, [키워드] acute respiratory syndrome B.1.525 B.1.617 B.1.617.1 B.1.617.2 BNT162b2 vaccine coronavirus coronavirus disease Coverage COVID-19 elicited genetic background geometric mean immunization India lineages neutralization neutralize neutralized Nigeria pandemic pathogenicity plaque reduction neutralization SARS-CoV-2 SARS-CoV-2 variant second dose sera serum sample spike glycoprotein strain Support susceptibility tested therapeutic titre Transmissibility USA-WA1/2020 Vaccine variant virus virus strain volunteers [DOI] 10.1038/s41586-021-03693-y [Article Type] Research
Detection of R.1 lineage severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with spike protein W152L/E484K/G769V mutations in Japan스파이크 단백질 W152L/E484K/G769V 돌연변이가있는 R.1 계통 계통 심각한 급성 호흡기 증후군 코로나 바이러스 2 (SARS-COV-2)의 검출Research Article Published on 2021-06-072022-08-13 Journal: PLoS Pathogens [Category] MERS, SARS, 변종, 유전자 메커니즘, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alter Author Avian Influenza binding domain clade coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 detection domain E484K epidemiological escape mutation examined family members genomic GISAID database had no hallmark infected with SARS-CoV-2 Influenza initiative Japan life Lineage lineages MONITOR Mutation mutations N-terminal domain natural selection Nextstrain Novel coronavirus nucleic acid Patient RBD Research respiratory SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences SARS-CoV-2 isolate SARS-CoV-2 isolates Sequencing severe acute respiratory syndrome Coronavirus Spike protein spike protein RBD Spike proteins Spread TaqMan the spike protein the United State The United States Transmissibility United States variant variants Viral viral fitness virulence virus strain whole genome Whole genome sequencing Wuhan Wuhan, China [DOI] 10.1371/journal.ppat.1009619 PMC 바로가기 [Article Type] Research Article
Genome-wide analysis of 10664 SARS-CoV-2 genomes to identify virus strains in 73 countries based on single nucleotide polymorphism단일 염기 다형성을 기반으로 73개국의 바이러스 균주를 식별하기 위한 10664 SARS-CoV-2 게놈의 게놈 전체 분석Article Published on 2021-06-012022-09-11 Journal: Virus research [Category] SARS, 변종, 치료법, [키워드] absence addition Analysis applied assessment Care Characteristics Cluster Clustering Clusters code Community Consensus country COVID-19 dataset determine environmental condition Evolution ExoN FIVE function genome-wide analysis Hamming distance Hierarchical hierarchical clustering identify linkage Measures Multiple Multiple sequence alignment mutated Non-synonymous Non-synonymous SNP NSP2 nucleocapsid nucleotide ORF3a performed polymorphism Protein provided Q57H Quantitative reported Research responsible SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 strain SARS-CoV-2 strains sequence Sequence alignment shown Silhouette single nucleotide Single nucleotide polymorphism SNP SNPs stability structures synonymous SNP T85I tendency Vaccine Vaccine design Validity virus virus strain virus strains Visual website [DOI] 10.1016/j.virusres.2021.198401 PMC 바로가기 [Article Type] Article
Surge of severe acute respiratory syndrome coronavirus 2 infections linked to single introduction of a virus strain in Myanmar, 20202020년 미얀마에서 바이러스 균주의 단일 도입과 관련된 중증 급성 호흡기 증후군 코로나바이러스 2 감염 급증Article Published on 2021-05-132022-09-10 Journal: Scientific Reports [Category] SARS, 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis B.1.1 B.6 Characteristics China clade collected coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 disease disease control Diseases early phase Epidemiology Evidence evidence of FIVE genetics Genome genome analysis genomic genomic data Health India Infection information International investigated Lineage Local local spread Malaysia Microbiology Molecular biology Molecular medicine Mutation no evidence of pandemic Phylogenetic analysis Prevention strategy provide reported respiratory SARS-CoV-2 SARS-COV-2 infection second wave severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Singapore specimen Spread the SARS-CoV-2 Transmission Travel variant virus virus strain Whole-genome sequence whole-genome sequences [DOI] 10.1038/s41598-021-89361-7 PMC 바로가기 [Article Type] Article