Human placenta-derived mesenchymal stem cells transplantation in patients with acute respiratory distress syndrome (ARDS) caused by COVID-19 (phase I clinical trial): safety profile assessmentClinical Trial Published on 2022-07-282022-10-05 Journal: Stem Cell Research & Therapy [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory distress acute respiratory distress syndrome (ARDS) administration adverse event Allogeneic Anti-inflammatory ARDS baseline cause caused Cell Cell therapy clinical Clinical sign clinical trial control group coronavirus COVID-19 COVID-19 pandemic death in COVID-19 demonstrated distress dose Efficacy enrolled evaluate evaluated feasible Health Hospitalization Human immunomodulatory injection intensive care intravenous Intravenous injection intravenously laboratory parameter Laboratory test mesenchymal stem cell morbidity and mortality not significantly different oxygen saturation participant Patient patients patients with ARDS patients with COVID-19 Phase I PL-MSC PL-MSCs Placenta mesenchymal stem cells (PL-MSC). protocol regenerative registry repeated Safe Safety assessment safety profile serum single dose standard treatment stem cell subject syndrome Treatment treatment group two group [DOI] 10.1186/s13287-022-02953-6 PMC 바로가기 [Article Type] Clinical Trial
SARS-CoV-2 Infection in Health Care Workers of Trieste (North-Eastern Italy), 1 October 2020-7 February 2022: Occupational Risk and the Impact of the Omicron Variant트리에스테(이탈리아 북동부) 의료 종사자의 SARS-CoV-2 감염, 2020년 10월 1일-2022년 2월 7일: 직업적 위험과 오미크론 변종의 영향Article Published on 2022-07-282022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] biological risk Cambridge Care circulation Contagion Coverage COVID-19 declined doses greater HCW HCWs Health Health care Health care worker health care workers health care-associated infection health protection health protection measures Hospitalization Impact implementation Infection Italy job job task Moderna New York occupational occupational risk omicron Omicron variant Pfizer risk risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections Trieste university USA vaccination vaccine dose Vaccines variant virus were recorded worker Workplace [DOI] 10.3390/v14081663 PMC 바로가기 [Article Type] Article
Real-life data on monoclonal antibodies and antiviral drugs in Italian inborn errors of immunity patients during COVID-19 pandemic코로나19 팬데믹 기간 동안 이탈리아 선천성 면역질환 환자의 단클론항체 및 항바이러스제 실생활 데이터Article Published on 2022-07-282022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] Alpha Analysis Antiviral antiviral agent Antiviral agents antiviral drug antiviral drugs Asymptomatic Care circulating Cohort contributed Course COVID-19 COVID-19 pandemic COVID-19 severity disease disease severity duration of viral shedding Effect Efficacy error evaluated Hospital admission Hospitalization hospitalization-risk hospitalizations hospitalized patients ICU admission Immunity immunized Inborn Inborn errors inborn errors of immunity Infection Italian longitudinal lower risk mAbs mitigate monoclonal monoclonal antibodies monoclonal antibody Mortality mRNA vaccine mRNA vaccines offered Patient patients treated performed positive Prevent prophylactic measure prophylactic measures Re-infection Re-infections reduce reduced Reinfection reported respond risk Safe SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 positivity SARS-CoV-2 strains SARS-CoV-2 virus severe COVID-19 severe disease Spectrum Spread Strains therapeutic therapy treated vaccination Vaccinations Viral viral shedding viral strain viral strains widespread [DOI] 10.3389/fimmu.2022.947174 PMC 바로가기 [Article Type] Article
Impact of tenofovir on SARS-CoV-2 infection and severe outcomes among people living with HIV: a propensity score-matched studySARS-CoV-2 감염 및 HIV 감염자의 심각한 결과에 대한 테노포비르의 영향: 성향 점수 일치 연구Article Published on 2022-07-282022-09-11 Journal: Journal of Antimicrobial Chemotherapy [Category] COVID19(2023년), SARS, 치료제, [키워드] 95% CI 95% confidence interval adjusted adjusted odds ratio Analysis antiretroviral association baseline characteristics Clinical outcome Cohort conducted Cox regression model Diagnosis disease severity emtricitabine evaluated Hospitalization Impact intrinsically logistic regression models management modify Odds ratio outcome outcomes PLWH Propensity score recipient recipients reduced report SARS-CoV-2 SARS-COV-2 infection Spain TDF/FTC tenofovir Tenofovir alafenamide tenofovir disoproxil tenofovir disoproxil fumarate therapeutic with HIV [DOI] 10.1093/jac/dkac177 PMC 바로가기 [Article Type] Article
Efficacy and effectiveness of SARS-CoV-2 vaccines for death prevention: A protocol for a systematic review and meta-analysis사망 예방을 위한 SARS-CoV-2 백신의 효능 및 효과: 체계적인 검토 및 메타 분석을 위한 프로토콜Article Published on 2022-07-282022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, meta-analysis, SARS, [키워드] adverse event all-cause mortality analyzed approved assessment Bia calculated case-control studies case-control study Cohort controlled trials COVID-19 death deaths effective Effectiveness Efficacy Egger eligible Evidence exploratory for inclusion forest plot forest plots funnel plot hazard hazard ratios heterogeneity Hospitalization incident independent intervals Intervention Meta-analysis Mortality Observational data outcome Placebo Prevent Primary outcome PROSPERO protocol Publication bia publication bias randomized control trial Randomized controlled trials RCT Record reducing Registered risk reduction SARS-CoV-2 vaccine SARS-CoV-2 vaccines Secondary outcomes Severe case severe cases statistical statistical test systematic review the vaccine the vaccines university vaccination Vaccination Status Vaccine visual inspection York [DOI] 10.1371/journal.pone.0265414 PMC 바로가기 [Article Type] Article
Contribution of Two-Dose Vaccination Toward the Reduction of COVID-19 Cases, ICU Hospitalizations and Deaths in Chile Assessed Through Explanatory Generalized Additive Models for Location, Scale, and Shape위치, 규모 및 모양에 대한 설명 일반화 가법 모델을 통해 평가된 칠레의 COVID-19 사례, ICU 입원 및 사망 감소를 위한 2회 접종 백신의 기여Article Published on 2022-07-272022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 변종, [키워드] Additive adverse outcome adverse outcomes booster dose booster doses contribute country COVID-19 death deaths dose epidemiological epidemiological data explain explanatory models Future future work GAMLSS models Generalized highlight Hospitalization ICU ICU hospitalizations Inclusion initial location mass vaccination Model outcome pandemic pandemic progresses per day Policy predictor provide R 2 reduce reducing SARS-COV-2 infection scale second dose shape statistical interaction statistically significant Stress Support vaccination vaccination schedule Vaccination Status vaccine doses Vaccines variant were used [DOI] 10.3389/fpubh.2022.815036 PMC 바로가기 [Article Type] Article
Assessment of unvaccinated and vaccinated patients with coronavirus disease 2019 (COVID-19) treated with monoclonal antibodies during the delta wave (July 1-August 20, 2021): a retrospective observational monocentric study델타 웨이브(2021년 7월 1일~8월 20일) 동안 단일 클론 항체로 치료한 코로나바이러스 질병 2019(COVID-19)에 대한 백신 접종 및 예방 접종을 받지 않은 환자의 평가: 후향적 관찰 단일 중심 연구Observational Study Published on 2022-07-272022-09-11 Journal: BMC Infectious Diseases [Category] MERS, 변종, 임상, 진단, [키워드] Administered Admission antibody assessment B.1.617.2 Casirivimab casirivimab/imdevimab conducted coronavirus coronavirus disease coronavirus disease 19 COVID-19 COVID-19 infection COVID-19 progression criteria death Delta delta variant Delta wave disease eligibility criteria emergency department EUA feasibility highest Hospital admission Hospitalization Imdevimab mAb median median age Mild-to-moderate monoclonal antibodies monoclonal antibody observational study outcome Patient patients Prevent Primary outcome recipient retrospective risk SARS-CoV-2 variant SARS-CoV-2 variant B.1.617.2 statistically therapy treated Treatment outcome unvaccinated Vaccinated vaccination Vaccination Status [DOI] 10.1186/s12879-022-07626-6 PMC 바로가기 [Article Type] Observational Study
The pandemic within the pandemic: the surge of neuropsychological disorders in Italian children during the COVID-19 eraObservational Study Published on 2022-07-272022-10-04 Journal: Italian Journal of Pediatrics [Category] 임상, [키워드] Admission Admissions caused children condition consequence COVID 19 COVID-19 COVID-19 pandemic COVID19 Department Depression diagnose disorder disorders Emergency facilitate Health Hospitalization ideation impairment increase in information involved Isolation Italian material measure mental health multicenter observational study Neuropsychological disorders. pandemic Patient pediatric physical Psychological recommendations required retrospective significant increase Society Stress study period Symptoms Treatment were recorded [DOI] 10.1186/s13052-022-01324-4 PMC 바로가기 [Article Type] Observational Study
The Risk of Obstetrical Hemorrhage in Placenta Praevia Associated with Coronavirus Infection Antepartum or Intrapartum코로나바이러스 감염과 관련된 근위태반의 산과 출혈 위험 분만 전 또는 분만 중Article Published on 2022-07-272022-09-11 Journal: Medicina [Category] COVID19(2023년), SARS, 치료기술, [키워드] analyzed antepartum Birth bleeding Childbirth Complication conducted COVID driven by evaluate first trimester group hemorrhage Hemostasis histological change Hospitalization hypertension identify incidence increase infected patients Infection intrapartum labor material no infection objective obstetrical bleeding occurred Patient patients Placenta placenta accreta placenta previa placenta previa. Pregnancy pregnancy-induced hypertension Prematurity presenting Result Retrospective study risk SARS-CoV-2 SARS-COV-2 infection severity significantly Signs and symptoms similarities specific treatment statistically significant difference stratified Symptoms three groups time of delivery viral disease viral infection with infection [DOI] 10.3390/medicina58081004 PMC 바로가기 [Article Type] Article
Are Pain Polymorphisms Associated with the Risk and Phenotype of Post-COVID Pain in Previously Hospitalized COVID-19 Survivors?이전에 입원한 COVID-19 생존자의 통증 다형성이 COVID-19 이후 통증의 위험 및 표현형과 관련이 있습니까?Article Published on 2022-07-262022-09-11 Journal: Genes [Category] 변종, [키워드] All participants Anxiety association BDNF carried clinical feature Clinical features cognitive collected COMT COVID-19 de novo depressive distribution distributions Features female Gender Genotype Hospitalization hospitalized COVID-19 HTR1B involved kinesiophobia long-COVID Musculoskeletal neuropathic neuropathic pain no differences no effect not significantly different nucleotide OPRM1 Pain participant Participants participated phenotypic feature phenotypic features polymerase chain reaction polymerase chain reactions polymorphism Post-COVID Psychological risk rs4680 rs6265 selected sensitization single nucleotide Single nucleotide polymorphism sleep quality SNP SNPs survivor Survivors Symptom Symptoms variable variant were assessed [DOI] 10.3390/genes13081336 PMC 바로가기 [Article Type] Article