Dipeptidylpeptidase-4 levels and DPP4 gene polymorphisms in patients with COVID-19. Association with disease and with severityCOVID-19 환자에서 Dipeptidylpeptidase-4 수준 및 DPP4 유전자 다형성.질병과의 연관성 및 심각성Article Published on 2021-07-012022-08-31 Journal: Life sciences [Category] SARS, 바이오마커, 유전자 메커니즘, 진단, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Alanine alanine aminotransferase albumin Analysis angiotensin Angiotensin converting enzyme-2 angiotensin-converting enzyme-2 association carrier cause controls coronavirus correlated COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients Dipeptidyl peptidase-4 Dipeptidylpeptidase-4 disease DPP4 enzyme fibrinogen functional Genotype healthy control healthy controls high risk Invasive mechanical ventilation lowest mechanical ventilation Neutrophils not need Patient patients with COVID-19 Platelet polymorphism Polymorphisms quantified receptor reported required respiratory SARS-CoV-2 serum severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity suggested TaqMan assays virus with COVID-19 [DOI] 10.1016/j.lfs.2021.119410 PMC 바로가기 [Article Type] Article
Nationwide seroprevalence of SARS-CoV-2 and identification of risk factors in the general population of the Netherlands during the first epidemic waveOriginal Research Published on 2021-06-302022-10-29 Journal: Journal of epidemiology and community health [Category] COVID-19, [키워드] 95% CI Analysis children Community Concentration COVID-19 epidemic detect Dyspnoea enrolled epidemic wave Epidemics Epidemiology estimate Fever fingerstick blood General population group higher odd highest identify IgG antibody Immunosuppressant Inclusion independent infected with SARS-CoV-2 Infection Intervention Logistic regression lowest measure median Netherland no difference participant Protective provided public health quantified questionnaire reported Result risk factor SARS-CoV-2 seronegative seropositive Seroprevalence serum antibody significantly higher Surveillance Symptom vaccination [DOI] 10.1136/jech-2020-215678 PMC 바로가기 [Article Type] Original Research
A Comparison of Depression and Anxiety among University Students in Nine Countries during the COVID-19 PandemicArticle Published on 2021-06-292022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] activity addressed Adults ANOVA Anxiety country COVID-19 COVID-19 pandemic Cross-national study Czech Republic Depression exposure to female GAD-7 Gender general self-reported health Generalized Germany high risk highest Impact less lowest mental health nine occurred pandemic participant Perceived Perspective physical activity Poland predictor risk risk factor Russia significant difference Slovenia student students Turkey Ukraine university [DOI] 10.3390/jcm10132882 PMC 바로가기 [Article Type] Article
Facial Self-Touching and the Propagation of COVID-19: The Role of Gloves in the Dental PracticeArticle Published on 2021-06-292022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] Adults Anxiety anxiety symptom blood pressure Contagion COVID-19 dental elevated facial Factor glove greater high risk illness incidence introduced Kinect lowest Measures occurred participant Perception Practice preventive measures Propagation reduction in role SARS–CoV–2 STAI subject touch Transmission were recorded [DOI] 10.3390/ijerph18136983 PMC 바로가기 [Article Type] Article
Perceptions towards COVID-19 and adoption of preventive measures among the public in Saudi Arabia: a cross sectional studyResearch Article Published on 2021-06-292022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] adoption Anxiety applied association chi-square tests COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19 virus cross cross-sectional survey early phase Effectiveness evaluate Factor flu group groups Guidance Health hygiene Infectious disease information Intervention less life-threatening lockdown Logistic regression lowest majority management media objective Older pandemic percentage percentages Perception preventive measure preventive measures public health question regions reported Result Risk perception Saudi Arabia self-isolate Self-isolation significant increase social distancing socio-demographic Spread supplementary material Symptom variables virus WhatsApp [DOI] 10.1186/s12889-021-11223-8 PMC 바로가기 [Article Type] Research Article
Benchmarking the Ability of Common Docking Programs to Correctly Reproduce and Score Binding Modes in SARS-CoV-2 Protease MproSARS-CoV-2 Protease Mpro에서 결합 모드를 올바르게 재현하고 점수를 매기는 일반적인 도킹 프로그램의 능력 벤치마킹Article Published on 2021-06-282022-09-11 Journal: Journal of Chemical Information and Modeling [Category] SARS, 치료제, [키워드] Ability advance AutoDock AutoDock vina Benchmarking benefit binding binding mode Care common comprehensive strategy conjunction conserved coronavirus coronavirus SARS-CoV-2 COVID-19 crystal structure crystal structures deviation docking docking method drug target drugs targeting enzyme free energy Glide homolog identify in silico knowledge Ligand lowest M pro mode MPro predict Program protease root Root-mean-square deviation SARS-CoV-2 score tested Virtual screening [DOI] 10.1021/acs.jcim.1c00263 PMC 바로가기 [Article Type] Article
A newly identified linear epitope on non-RBD region of SARS-CoV-2 spike protein improves the serological detection rate of COVID-19 patientsSARS-COV-2 스파이크 단백질의 비 RBD 영역에서 새로 확인 된 선형 에피토프는 COVID-19 환자의 혈청 학적 검출 속도를 향상시킵니다.Research Published on 2021-06-262022-09-01 Journal: BMC Microbiology [Category] MERS, 진단, 치료기술, [키워드] addition analyzed antibody Antigen asymptomatic infection asymptomatic infections asymptomatic patients B cell B cell linear epitopes Combination convalescent sera convalescent serum convenience correlation COVID-19 patient detect detection rate ELISA epitope epitope peptide Epitopes exhibited fast feasibility highest Humoral immunity identify IMPROVE Infectious disease Infectious diseases information lack linear linear epitopes lowest medium neutralizing antibody overlapping Patient peptide peptide-based peptides positive positive correlation positive rate Protein reaction rate reactivity reported Research Result S protein SARS-CoV-2 SARS-CoV-2 spike protein serological serological data serum samples significantly Spike protein subsequent supplementary material Support the S protein titre total patient total patients with COVID-19 [DOI] 10.1186/s12866-021-02241-y PMC 바로가기 [Article Type] Research
Psychological Determinants of COVID-19 Vaccine Acceptance among Healthcare Workers in Kuwait: A Cross-Sectional Study Using the 5C and Vaccine Conspiracy Beliefs ScalesArticle Published on 2021-06-252022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acceptance analyses anti-vaccine appear belief benefit characteristic conducted coronavirus disease COVID-19 COVID-19 vaccination COVID-19 vaccine dentist determinant evaluate females group HCW HCWs healthcare worker highest Infection intention to vaccinate knowledge Kuwait Laboratory lowest majority Middle East mRNA vaccine Nurse pandemic participant Patient Pfizer-BioNTech physician predictor Psychological Release reported risk SARS-CoV-2 SARS-CoV-2 prevention scale significantly social media platforms Spread study participant vaccination Vaccine Vaccine hesitancy vaccine rejection were assessed worker [DOI] 10.3390/vaccines9070701 PMC 바로가기 [Article Type] Article
Odds Ratio Estimation of Medical Students’ Attitudes towards COVID-19 VaccinationArticle Published on 2021-06-252022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] Attitude conducted coronavirus COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional dose effective estimation information investigated lowest median age medical students provide questionnaire Ratio second wave Side effect Slovakia Spread vaccination vaccination rate was performed women [DOI] 10.3390/ijerph18136815 PMC 바로가기 [Article Type] Article
Detection and viral RNA shedding of SARS-CoV-2 in respiratory specimens relative to symptom onset among COVID-19 patients in Bavaria, Germany독일 바이에른의 COVID-19 환자의 증상 발병과 관련하여 호흡기 표본에서 SARS-CoV-2의 검출 및 바이러스 RNA 방출Article Published on 2021-06-232022-09-11 Journal: Epidemiology and Infection [Category] SARS, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome Chain Reaction clearance comparable coronavirus coronavirus disease COVID-19 COVID-19 cases COVID-19 patient Ct-value Ct-values cycle threshold detection diagnostic diagnostic sensitivity estimate Germany individual Kaplan-Meier plot Kaplan-Meier plots lowest Patient patients presymptomatic transmission Probability proportion remained reported respiratory specimen reverse transcriptase reverse transcriptase-polymerase chain reaction Ribonucleic acid RNA RT-PCR sampling SARS-CoV-2 SARS-CoV-2 detection scatterplot sensitivity Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 specimen subset symptom onset symptomatic tested the timing Viral load viral ribonucleic acid Viral RNA Viral RNA shedding was used were used [DOI] 10.1017/S0950268821001345 PMC 바로가기 [Article Type] Article