Use of Physiological Data From a Wearable Device to Identify SARS-CoV-2 Infection and Symptoms and Predict COVID-19 Diagnosis: Observational Study웨어러블 기기의 생리학적 데이터를 사용하여 SARS-CoV-2 감염 및 증상 식별 및 COVID-19 진단 예측: 관찰 연구Original Paper Published on 2021-02-222022-09-12 Journal: Journal of Medical Internet Research [Category] MERS, 진단, [키워드] amplitude app Apple Watch autonomic Autonomic nervous system Chain Reaction change changes in characterized collected COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19–related symptoms data Device Diagnosis diagnosis of COVID-19 downloaded follow-up period Health care heart rate heart rate variability HRV identification identify individual Infection Infectious disease Metrics Mount Sinai Mount Sinai Health System nasal swab nervous system function objective Observational observational study participant performed physiological polymerase chain polymerase chain reaction predict prediction Predictive question Result SARS-CoV-2 Significant significant changes in Standard deviation subject survey Symptom Symptoms System the mean uninfected Variability Warrior wearable wearable device with infection [DOI] 10.2196/26107 PMC 바로가기 [Article Type] Original Paper
Identification and functional analysis of the SARS-COV-2 nucleocapsid proteinSARS-COV-2 뉴클레오캡시드 단백질의 동정 및 기능분석Research Article Published on 2021-02-222022-09-10 Journal: BMC Microbiology [Category] MERS, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect Analysis analyzed applied biological function coil composed conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 depth analysis Drug discovery flow cytometry functional Health Organization hydrophobic identification identify increased expression kinases mass spectrometry MERS-CoV N protein nuclear protein nucleocapsid nucleocapsid protein Nucleocapsid protein (N protein) phosphorylated Phosphorylation phosphorylation site phosphorylation sites physicochemical Physicochemical properties Pneumonia predicted prediction Protein protein kinase protein kinases ProtParam tool PROVEAN random reliability respiratory Result SARS-CoV SARS-CoV-2 SARS-CoV-2 nucleocapsid server severe acute respiratory syndrome Coronavirus significantly similarity SOPMA tool Structure subcellular localization supplementary material target targets tertiary structure therapeutic targets transfected with TUBA1C TUBB6 Vaccine virus widespread World Health Organization [DOI] 10.1186/s12866-021-02107-3 PMC 바로가기 [Article Type] Research Article
Prognosis Score System to Predict Survival for COVID-19 Cases: a Korean Nationwide Cohort StudyOriginal Paper Published on 2021-02-222022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, MERS, [키워드] Absolute lymphocyte count Accuracy addition adjusted hazard ratio allocation Analysis analyzed assist characteristic Cohort COVID-19 COVID-19 case COVID-19 diagnosis COVID-19 pandemic COVID-19 prognosis Decision making Dementia develop died Digital health disease management disease severity Dyspnea evaluated Factor Factors group groups Hospital stay identify initial intensive care Korean laboratory-confirmed Length of stay medical resource Medical resources Mental Mortality nonsurvivor objective Older age parameter Patient patients with COVID-19 predict prediction Predictive Prognosis Randomly receiving Regression model renal Result risk score scoring system significantly survival survival rate survivor System Triage validation cohort [DOI] 10.2196/26257 PMC 바로가기 [Article Type] Original Paper
Innate Receptor Activation Patterns Involving TLR and NLR Synergisms in COVID-19, ALI/ARDS and Sepsis Cytokine Storms: A Review and Model Making Novel Predictions and Therapeutic SuggestionsReview Published on 2021-02-202022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, [키워드] “cytokine storm” activate Activation acute lung injury acute lung injury (ALI) acute respiratory distress acute respiratory distress syndrome (ARDS) Bacterial Bacterial coinfection characteristic characterized Combination coronavirus COVID-19 Cytokine release syndrome Cytokine storm effective eight Evidence exhibiting fungal fungal coinfection Fungal infection fungal infections healthy control hyperinflammation implication Infection Innate Innate immunity Interaction Involving Making mechanism melatonin microbes Mild mild cases mild COVID-19 patient Model NLR NLRP3 novel nucleotide-oligomer-recognition-domain-like receptors (NLR) oligomerization outlined pattern prediction receptor respiratory resulting review SARS-CoV-2 Sepsis severe COVID-19 severe COVID-19 patients suggestion Symptoms syndrome synergistic synergy therapeutic TLR TLR antagonists TLR2 TLR3 TLR4 TLR7 TLR9 Toll-like receptor toll-like receptors (TLR) treating COVID-19 [DOI] 10.3390/ijms22042108 PMC 바로가기 [Article Type] Review
Machining learning predicts the need for escalated care and mortality in COVID-19 patients from clinical variablesResearch Paper Published on 2021-02-182022-10-29 Journal: International Journal of Medical Sciences [Category] COVID-19, MERS, [키워드] Admission age Algorithm Analysis approach artificial intelligence AUC Care characteristic clinical decision clinical parameter clinical variable collected Comorbidities coronavirus 2 (SARS-CoV-2) COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 positive patient D-dimer demographic develop evaluated female ferritin Hospital admission ICU ICU admission identify independent Infection intensive care Laboratory test lactate dehydrogenase Lung infection Lymphocytes machine learning algorithm Machining material measure Mortality New York oxygen saturation Patient performance physician Pneumonia predict predicted prediction Predictive predictor Primary outcome procalcitonin Protein pulse Retrospective study ROC Symptoms temperature translation university vitals with COVID-19 [DOI] 10.7150/ijms.51235 PMC 바로가기 [Article Type] Research Paper
CANPT Score: A Tool to Predict Severe COVID-19 on AdmissionMedicine Published on 2021-02-182022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI Accuracy Admission albumin AUROC body temperature characteristic China Clinical data collected Comorbidities coronavirus disease COVID-19 COVID-19 patient creatinine Critical cut-off value death diagnosed with COVID-19 Effectiveness eight enrolled evaluate group hospital independent risk factor Laboratory Logistic material Mortality mortality rate Neutrophil-to-lymphocyte ratio NLR nomogram Patient patients died patients with COVID-19 percentage Platelet predict prediction Predictive risk SARS-CoV-2 severe disease severe illness severity the patient total bilirubin variable were used with COVID-19 [DOI] 10.3389/fmed.2021.608107 PMC 바로가기 [Article Type] Medicine
A Prediction Model to Prioritize Individuals for a SARS-CoV-2 Test Built from National Symptom Surveys국가 증상 설문조사에서 구축된 SARS-CoV-2 테스트를 위해 개인을 우선시하는 예측 모델Article Published on 2021-02-122022-09-11 Journal: Med (New York, N.Y.) [Category] SARS, 치료기술, 치료제, [키워드] age Analysis applicability artificial artificial intelligence AUROC Ben can be used center clinical manifestation collected combating Council COVID-19 COVID-19 diagnosis Data science dataset demonstrated Diagnosis education effective European exposure to family foundation funding gold gold standard groups H.R Health Policies high risk higher education Human individual Interaction Lady limitation machine machine learning Marco Minerva Model National New PCR positive positive individual positive individuals positive test result prediction Probability question Research resource SARS-CoV-2 SARS-COV-2 infection Science scientist supported survey suspected patients Symptom Test test result the disease utility Variation Viral Viral RNA Weizmann White Rose [DOI] 10.1016/j.medj.2020.10.002 PMC 바로가기 [Article Type] Article
Association between peripheral lymphocyte count and the mortality risk of COVID-19 inpatients말초 림프구 수와 COVID-19 입원 환자의 사망률 사이의 연관성Research Article Published on 2021-02-112022-09-01 Journal: BMC Pulmonary Medicine [Category] Fulltext, MERS, 진단, [키워드] 95% CI Admission Analysis Characteristics clinical utility collected confounding factors coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients death death in COVID-19 decision curve analysis hospital hospitalized patient increased mortality Infection Inpatient Inpatients Laboratory tests lymphocyte Lymphocyte count Mortality mortality risk Multiple Multiple regression analysis Non-linear relationship outcome Patient peripheral lymphocyte prediction Predictive predictive power Predictive value regression analysis Result risk significantly higher supplementary material the patient threshold was used Wuhan [DOI] 10.1186/s12890-021-01422-9 PMC 바로가기 [Article Type] Research Article
Prediction and control of COVID-19 spreading based on a hybrid intelligent modelResearch Article Published on 2021-02-112022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] addition Algorithm caused coronavirus COVID-19 death Epidemic Genetic Government Health Infection infection rate Infectious disease Measures media memory outbreak parameter predict prediction Predictive Simulation Treatment Wuhan, China [DOI] 10.1371/journal.pone.0246360 PMC 바로가기 [Article Type] Research Article
Genomic mutations and changes in protein secondary structure and solvent accessibility of SARS-CoV-2 (COVID-19 virus)SARS-CoV-2(COVID-19 바이러스)의 게놈 돌연변이 및 단백질 2차 구조 및 용매 접근성의 변화Article Published on 2021-02-102022-09-10 Journal: Scientific Reports [Category] MERS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis caused changes changes in coding gene coding genes coding region coding regions coronavirus COVID-19 pandemic COVID-19 virus D614G Data mining dataset deep learning Evolution facilitate genomic genomic mutation genomic mutations highly pathogenic Intervention Mutation mutation D614G ORF10 ORF6 ORF7a ORF7b pandemic Point mutation point mutations predicted prediction Protein researchers respiratory respond SARS-CoV-2 secondary structure severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 solvent Spike protein Spread tracing Transmission unlikely Vaccine Viral viral genome sequences virus virus spike protein [DOI] 10.1038/s41598-021-83105-3 PMC 바로가기 [Article Type] Article