Olfactory and Oral Manifestations of COVID-19: Sex-Related Symptoms—A Potential Pathway to Early DiagnosisSpecial Section on COVID-19 Published on 2020-06-162022-10-29 Journal: Otolaryngology--Head and Neck Surgery [Category] COVID-19, MERS, SARS, [키워드] absence ambulatory Anosmia approach Cluster Combination conducted coronavirus coronavirus disease cough COVID-19 COVID-19 disease COVID-19 patient diagnosing Diagnosis disorders dysgeusia facial Fever functions headache Health initial symptom limit manifestation men myalgia nasal congestion objective olfactory olfactory dysfunction oral outbreak Pain pandemic participated Patient Potential questionnaire recruited reported Result sense of smell sense of taste setting sore throat statistically significant Symptom Symptoms taste dysfunction Viral diseases virus weakness women Xerostomia [DOI] 10.1177/0194599820934380 PMC 바로가기 [Article Type] Special Section on COVID-19
COVID-19 Induced Hepatitis B Virus Reactivation: A Novel Case From the United Arab EmiratesInternal Medicine Published on 2020-06-152022-10-31 Journal: Cureus [Category] COVID-19, [키워드] abdominal pain acute on chronic liver disease acute respiratory syndrome adult gastroenterology alanine aminotransferase Altered mental status Aspartate aminotransferase Asymptomatic Care caused clinically coronavirus COVID COVID 19 COVID-19 diarrhea functions HBV Hepatitis B virus Hepatitis virus hepatology icteric impaired liver function increased risk induced liver Liver function novel Novel coronavirus novel coronavirus disease Patient prevalent RNA total bilirubin transaminitis UAE United Arab Emirate viral hepatitis b viral infection vomiting [DOI] 10.7759/cureus.8645 PMC 바로가기 [Article Type] Internal Medicine
Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes모노티올 글루타레독신 Grx3의 단백질체 프로파일링은 철 의존적 과정의 조절에서 그것의 전체적인 역할을 보여줍니다Research Article Published on 2020-06-112022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Affinity purification amplify applied approach associations biological processes Candida albican Candida albicans Cell cellular processes cofactor commensal component conserved Critical cytosolic determine DNA essential nutrient expression function functions fungal Gene Expression genotoxic glutaredoxin growth Grxs Heat shock histidine homeostasis Host human host humans in vivo interact iron iron homeostasis leucine maintain mass spectrometry metabolism mutant organism Organisms oxidative oxygen pathogen Pathogens performed Protein protein translation proteomic regulate Regulation regulatory circuit repair repression required respond reveal sulfur Support survival Taking target gene Target genes the cell Tryptophan utilization virulence [DOI] 10.1371/journal.pgen.1008881 PMC 바로가기 [Article Type] Research Article
Topological analysis of SARS CoV-2 main proteaseFast Track Published on 2020-06-092022-10-31 Journal: Chaos [Category] COVID-19, SARS, [키워드] acute respiratory syndrome Analysis average binding site catalytic site change coronavirus COVID-19 pandemic effective functions help inhibitor inhibitors interactions M pro medication Perturbation pharmacological target producing protease Protein residue SARS CoV SARS CoV-2 sensitivity whole protein [DOI] 10.1063/5.0013029 PMC 바로가기 [Article Type] Fast Track
Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)Article Published on 2020-06-082022-10-04 Journal: Cell Death and Differentiation [Category] SARS, 바이오마커, [키워드] Admission Analysis analyzed Biomarker Blood Cell circulating Concentration convalescent phase COVID-19 COVID-19 disease cytokine Disease progression disease severity effector T cells excessive immune response expansion expression Frequency functions IL-6 immune immune response in vitro increase in Infectious diseases inflammation marker Inflammatory cytokine longitudinal analysis lymphopenia massive Mild mild patients mononuclear cell mortality rate Pathogenesis Patient performed peripheral plasma samples profiles reducing reduction in required SARS-CoV-2 SARS-CoV-2-infected patients serum Severe case severe coronavirus disease severe COVID-19 severe COVID-19 disease severe disease Severe patient suppressed T cell T cells T-cell T-cell activation target TGF-β the patient therapeutic approaches to define was obtained was performed was tested [DOI] 10.1038/s41418-020-0572-6 PMC 바로가기 [Article Type] Article
Evolution of Salmonella enterica serotype Typhimurium driven by anthropogenic selection and niche adaptation살모넬라 엔테리카 혈청형 Typhimurium의 인위적 선택과 틈새 적응에 의한 진화Research Article Published on 2020-06-082022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 살모넬라증, [키워드] a minor accumulation acquisition acting adaptation Affect affecting anthropogenic antimicrobial resistance Biology Characteristics characterized circulation clade clone coding sequence coding sequences composed convergent evolution disease disease potential distribution Diversity driven by drug resistance elements elevated Epidemics Epidemiology Evolution exhibit exhibited food safety framework function functional functions Gain gastroenteritis Genes Genetic genomes genotypic genotypic variation group Health Host host adaptation host range host-pathogen interactions human infection IMPROVE Infection information invasive isolate isolates Laboratory less Lineage livestock minor monophasic observation organism outcome pandemic pathogen pathogenicity Population predicted predisposition prophage provide Recombination reflected risk Salmonella Salmonella Typhimurium sequence Sequencing serotype serotypes strain Strains subclade subclades subgroup subgroups survival undergo Variation whole genome Whole genome sequencing [DOI] 10.1371/journal.pgen.1008850 PMC 바로가기 [Article Type] Research Article
Computational analysis of microRNA-mediated interactions in SARS-CoV-2 infectionBioinformatics Published on 2020-06-052022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] addition Analysis Basal transcription candidate cellular processe complex component coronavirus 2 COVID19 Defense E protein EGFR element example expression Factor functions Gene Expression gene function generate Hairpin Host Host–virus interaction human gene human genes human miRNA identify in viral indicated Interaction involved mechanism MED1 MED12L MED19 MED9 metabolism microRNA miRNA miRNA-based therapy miRNAs modulating ORF10 ORF1ab ORF3a ORF7a ORF8 Organisms performed precursor predicted Regulatory respiratory RNA virus SARS-CoV-2 SARS-COV-2 infection searched sequence signaling pathway Stat1 TAF4 TAF5 TAF7L target targeting the SARS-CoV-2 genome Transcription transcription factor transcriptional translation viral gene viral genes viral miRNA viral miRNAs viral replication virus virus genome Wnt [DOI] 10.7717/peerj.9369 PMC 바로가기 [Article Type] Bioinformatics
An Off-the-Shelf Approach for the Production of Fc Fusion Proteins by Protein Trans -Splicing towards Generating a Lectibody In VitroArticle Published on 2020-06-032022-10-29 Journal: International Journal of Molecular Sciences [Category] Coronavirus, SARS, [키워드] antibodies antibody fragment approach binding binding domain binding site demonstrated domain domains Escherichia coli expression Fc functions fused fusion fusions Genetic HIV IgG Immunoglobulin G in vitro Infectious disease inhibit lectibody lectin N-terminus Organisms potential therapeutic agent produced producing Production Protein protein trans-splicing protein ligation SARS Coronavirus scytovirin segmental isotopic labeling split intein therapeutic Tran virus entry [DOI] 10.3390/ijms21114011 PMC 바로가기 [Article Type] Article
Evolutionary Analysis of Infectious Bronchitis Virus Reveals Marked Genetic Diversity and Recombination EventsArticle Published on 2020-05-292022-10-31 Journal: Genes [Category] Coronavirus, MERS, [키워드] affecting Analysis avian coronavirus bronchitis circulating Clustering collected disease Diversity domain Evolution functions Genetic Genotype genotypes globe help highlight IBV in viral Infectious Bronchitis Virus involved isolate Kingdom Lineage mechanism natural selection nine nucleocapsid outbreak PCR positive Protein real-time reverse transcriptase Recombination recombination event reported Result resulting Saudi Arabia selective pressure serotype Spread strain Strains vaccination Vaccine Vaccines virus viruses were used widespread [DOI] 10.3390/genes11060605 PMC 바로가기 [Article Type] Article
The Performance of the Iranian Red Crescent by Launching Testing Centers for the Coronavirus Disease코로나 바이러스 질병에 대한 테스트 센터를 시작하여이란 적신월의 성과Report from the Field Published on 2020-05-222022-09-10 Journal: Disaster Medicine and Public Health Preparedness [Category] MERS, SARS, 진단, 치료기술, [키워드] best center conducted coronavirus coronavirus disease COVID-19 Crescent fever detection functions New organization people with COVID-19 performance problem Red reducing Research respond screened Screening skin temperature Society temperature Testing Volunteer volunteering Year [DOI] 10.1017/dmp.2020.167 PMC 바로가기 [Article Type] Report from the Field