monocyte – Page 41 – Communicable Diseases Research

Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response

대식세포에서 엔도글린이 결핍된 마우스는 손상된 면역 반응을 보여줍니다

Research Article

Published on 2016-03-242022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

Cytomegalovirus viral load within blood increases markedly in healthy people over the age of 70 years

Research

Published on 2016-01-052024-09-02
Journal: Immunity & Ageing : I & A [Category] 대상포진,

[키워드] Ageing cytomegalovirus ddPCR lifespan monocyte
[DOI] 10.1186/s12979-015-0056-6 PMC 바로가기 [Article Type] Research

Malarial pigment hemozoin impairs chemotactic motility and transendothelial migration of monocytes via 4-hydroxynonenal

article

Published on 2014-10-312024-09-01
Journal: Free Radical Biology and Medicine [Category] 말라리아,

[키워드] 4-hydroxynonenal Actin Coronin Free radicals Hemozoin lipoperoxidation malaria Migration monocyte
[Article Type] article

Myosins 1 and 6, myosin light chain kinase, actin and microtubules cooperate during antibody-mediated internalisation and trafficking of membrane-expressed viral antigens in feline infectious peritonitis virus infected monocytes

Research

Published on 2014-02-122022-10-28
Journal: Veterinary Research [Category] Coronavirus,

Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases

단핵구 및 대식세포 분화: 염증성 질환에 대한 바이오마커로서의 순환 염증성 단핵구

Review

Published on 2014-01-072022-08-07
Journal: Biomarker Research [Category] Biochemistry,

[키워드] Biomarker broad spectrum cardiovascular diseases changes circulation dendritic cells environmental stimulation express various receptors functional phenotype heterogeneity heterogeneous human disease Indicator Infection inflammatory disease Inflammatory diseases inflammatory monocyte inflammatory monocyte subset inflammatory monocyte subsets inflammatory or anti-inflammatory knowledge Macrophage macrophages MONITOR monocyte monocyte differentiation monocyte heterogeneity Monocytes monocytosis murine potential mechanism rapid progress recruited Research subset suggested tissue tissue damage tissue macrophage tissue macrophages various inflammatory diseases
[DOI] 10.1186/2050-7771-2-1 PMC 바로가기 [Article Type] Review

Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases

기능성 IL6R 358Ala 대립유전자는 전통적인 IL-6 수용체 신호 전달을 손상시키고 다양한 염증성 질환의 위험에 영향을 미칩니다

Research Article

Published on 2013-04-042022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] 358Ala Abdominal aortic aneurysm affecting allele analyzed aortic aneurysm approach Arthritis Asp358Ala association Asthma Atrial fibrillation Author balance benefit Cambridge BioResource causal variant CD4+ T cell CD4+ T cells CHD Chronic diseases circulating cleavage clinical trial clinical trials common diseases complex complex diseases Concentration Control copy Coronary heart disease Critical cytokine diabete diabetes etiology Evidence expression functional Genetic genetic association Genetic variation heart disease human disease identify IL-6 IL-6 receptor IL-6 signaling IL-6R IL-6R signaling IL-6R signaling pathway IL6R Immune cell immune cells impairment implicated implication increase increase in independent Inflammatory Inflammatory responses influence interleukin interleukin-6 isoform mechanism membrane-bound molecular mechanism monocyte Monocytes mononuclear cell mononuclear cells Non-synonymous nucleotide Patient PBMCs Peripheral blood Peripheral blood mononuclear cells Phosphorylation polymorphism Population protein level protein levels RA reduce reduced reduction regulated Regulation rheumatoid arthritis risk rs2228145 Signaling sIL-6R single nucleotide Single nucleotide polymorphism soluble IL-6R Stat1 STAT3 Stimulation suggested surface expression surface receptor susceptibility T cells T1D therapeutic intervention therapy These data Transcription transcription factor transcription factors translate Treatment response Type 1 diabetes variant Variation Volunteer
[DOI] 10.1371/journal.pgen.1003444 PMC 바로가기 [Article Type] Research Article

Editorial: Macrophage heterogeneity and responses to influenza virus infection

Article

Published on 2012-07-012023-06-09
Journal: Journal of leukocyte biology [Category] 신종인플루엔자,

[키워드] alveolar macrophage cytokine H5N1 lung monocyte Pathogenesis
[DOI] 10.1189/jlb.0312130 PMC 바로가기

A Genome-Wide Association Scan on the Levels of Markers of Inflammation in Sardinians Reveals Associations That Underpin Its Complex Regulation

사르데냐인의 염증 표지자 수준에 대한 게놈 전체의 연관성 스캔은 복잡한 조절을 뒷받침하는 연관성을 보여줍니다

Research Article

Published on 2012-01-262022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] ABO gene AIRE APOC-I approach association associations Author autosomal C-reactive protein CADM3 CCR2 Cohort common disease complex conducted CR1 CRP CRP gene damaged cells DARC detect different different diseases Effects erythrocyte sedimentation erythrocyte sedimentation rate ESR Evidence Factor found functional Gene genetic determinant genetic determinants Genetic variant genetic variants genome-wide association scan Genome-wide association scans genome-wide significant genotyped GWAS HBB Health help High-sensitivity C-reactive protein highlight HNF1A hsCRP ICOSLG identifying IL-6 IL-6R gene ImmunoChip implicated IMPROVE included independent individual individuals Inflammation inflammation erythrocyte sedimentation rate Inflammatory biomarker interleukin interleukin-6 knowledge large cohort led to Level loci MCP-1 mechanism MetaboChip custom arrays molecular mechanism molecular mechanisms monocyte monocyte chemotactic protein-1 novel organism performed power pro-inflammatory molecule pro-inflammatory molecules Protective Protein provided QTLs Quantitative quantitative traits receptor Regulation replicated robust rs113459440 rs11829037 rs1205 rs12075 rs12567990 rs17141006 rs225918 rs3026968 rs3093077 rs3845624 rs4129267 rs4420638 rs4910472 rs657152 Sardinia Sardinian sedimentation rate selected SNP SPPL3 TMEM57 UCN119B UNC119B variant X chromosome SNP
[DOI] 10.1371/journal.pgen.1002480 PMC 바로가기 [Article Type] Research Article

SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1b

Research Article

Published on 2012-01-122022-10-28
Journal: PLoS ONE [Category] Coronavirus,

[키워드] Accessory accessory protein activity acute respiratory syndrome Affect AP-1 binding Cell cells cellular chemokine co-immunoprecipitation cytokine dendritic cells downstream genes elevated ENCODE ERK expressing finding found functions Genome Host IL2 increase in Infected Infection inhibitor Interaction interferon isoform kinase lab led to MIP-1α monocyte mRNA level Pathogenesis pharmacological Phosphorylation physiological promoter Protein recruitment related reporter gene assay Runt RUNX1 SARS Coronavirus SARS virus SARS-CoV target gene transcription factor transcriptional activity Treatment unique upregulated upregulating upregulation yeast
[DOI] 10.1371/journal.pone.0029542 PMC 바로가기 [Article Type] Research Article

Toll-like receptors, chemokine receptors and death receptor ligands responses in SARS coronavirus infected human monocyte derived dendritic cells

Research Article

Published on 2009-06-082022-10-27
Journal: BMC Immunology [Category] Coronavirus,