Human Monoclonal Antibodies against Highly Conserved HR1 and HR2 Domains of the SARS-CoV Spike Protein Are More Broadly NeutralizingResearch Article Published on 2012-11-212022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] Amgen antibody binding conserved convalescent patient different ectodomain effective expressing glycoprotein Human Human monoclonal antibody immune implication Infected isolates monoclonal antibody neutralize Neutralizing Patient produced pseudotyped virus Receptor binding domain Region respiratory S protein S1 domain S2 domain SARS-CoV SARS-CoV spike sequence sera severe shown Subunit vaccine the S protein therapeutic therapy Treatment variant viruses [DOI] 10.1371/journal.pone.0050366 PMC 바로가기 [Article Type] Research Article