COVID-19 vaccine hesitancy in periconceptional and lactating women: a systematic review and meta-analysis protocolArticle Published on 2022-11-072022-11-16 Journal: BMJ Open [Category] meta-analysis, [키워드] Analysis appear approval article caused CNKI Cochrane Library COVID-19 COVID-19 vaccine criteria data extraction determinant discrepancy disease effective Embryology Epidemiology Ethics Evidence gestation heterogeneity higher risk homogeneous indicated lack lactating lactating women lactation Meta-analysis meta-regression observational study outcome outcomes pandemic pandemic of COVID-19 peer-reviewed Pregnancy pregnant pregnant women Prevalence PROSPERO protocol provided receive reproductive reproductive medicine required Research resolved subject systematic review vaccination Vaccine hesitancy Web of Science WHO with COVID-19 women [DOI] 10.1136/bmjopen-2021-059514 PMC 바로가기
Preparing for pandemics: a systematic review of pandemic influenza clinical management guidelinesArticle Published on 2022-11-072022-11-15 Journal: BMC Medicine [Category] 치료제, [키워드] addressed AGREE II Antiviral treatment appraisal benefit Care children clinical Clinical management Clinical management guidelines COVID-19 pandemic evaluate Evidence guideline help heterogeneous highlight identify Immunosuppression implementation Influenza International management management guideline median morbidity and mortality MOST neuraminidase inhibitor New Older outcomes OVID oxygen pandemic Patient populations Practice pregnant women preparedness Preparing produced recommendation reduce Research risk searched Support supportive care systematic review therapy Treatment Trial Turning [DOI] 10.1186/s12916-022-02616-6 PMC 바로가기
Association between treatment failure and hospitalization after receipt of neutralizing monoclonal antibody treatment for COVID-19 outpatientsArticle Published on 2022-11-072022-11-16 Journal: BMC Infectious Diseases [Category] SARS, 변종, [키워드] 95% CI 95% confidence interval adjusted odds ratio Administered age Characteristics clinical trial Comorbidity COVID-19 COVID-19 outpatient death defined died early symptomatic COVID-19 effective Electronic health record health system Hospitalization Hospitalized immunocompromised status lack mAb mAbs Male sex Mild monoclonal antibodies monoclonal antibody monoclonal antibody treatment Mortality mortality data multicenter Neutralizing obesity Observational cohort study occurred pandemic Patient patients patients with COVID-19 positive Primary outcome real-world data reducing SARS-CoV-2 SARS-CoV-2 test SARS-CoV-2 vaccination Treatment Vaccine variants while [DOI] 10.1186/s12879-022-07819-z PMC 바로가기
Elucidating host cell response pathways and repurposing therapeutics for SARS-CoV-2 and other coronavirusesArticle Published on 2022-11-052022-11-15 Journal: Scientific Reports [Category] SARS, 신약개발, 치료제, [키워드] Analysis common cold Coronaviruses Compound COVID-19 COVID-19 therapeutics cytotoxicity effective gene expression profile globe Heat shock homoharringtonine host cell response host response in silico in vitro modulating other coronavirus pandemic pathway Prevent provided reported SARS-CoV-2 SARS-CoV-2 biology screened severe symptoms tanespimycin target tested unique Vaccine viral infection [DOI] 10.1038/s41598-022-21984-w PMC 바로가기
SARS-CoV-2 quasi-species analysis from patients with persistent nasopharyngeal sheddingArticle Published on 2022-11-042022-11-16 Journal: Scientific Reports [Category] SARS, 변종, [키워드] Analysis asked both groups clade Consequences Control COVID 19 deviation Evolution of SARS-CoV-2 genomic greater Human immune system immune evasion increase Infectious virus Interaction intra-individual investigated Mutation N501Y nasopharyngeal no significant difference P681H pandemic Patient patients performed persistence Prevent question RNA virus SARS-CoV-2 Sequencing Standard survival the SARS-CoV-2 therapeutic two group Variability variants viral propagation viral variant [DOI] 10.1038/s41598-022-22060-z PMC 바로가기
Updated vaccine protects against SARS-CoV-2 variants including Omicron (B.1.1.529) and prevents transmission in hamstersArticle Published on 2022-11-042022-11-15 Journal: Nature Communications [Category] SARS, 변종, 진단, 치료기술, [키워드] Antigen B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta block Community COVID-19 vaccine current Delta delta variant detectable Efficacy eliminating expressed Fever Gamma hamster immunization Lineage Lung pathology maintain Neutralizing antibody response omicron P.1 pandemic predominant Prevent PROTECT SARS-CoV-2 strains SARS-CoV-2 variant sequence Spread titre Transmission Vaccine variants variants of concern vectored vaccine virus VoC VOCs [DOI] 10.1038/s41467-022-34439-7 PMC 바로가기
Anxiety and depression in the post-pandemic era: concerns about viral mutation and re-outbreakArticle Published on 2022-11-032022-11-16 Journal: BMC Psychiatry [Category] SARS, 변종, [키워드] Anxiety changes in China city clinically Complete conducted convenience sampling coronavirus COVID-19 critically ill patients Depression difference East effective Factor female GAD-7 groups Health healthy help illness IMPROVE infected patient infected patients likelihood logistic regression model males mental health no significant difference outbreak pandemic Patient Perception PHQ-9 Population Psychological psychological reaction public health system question questionnaire Questionnaires reduced reported required risk factor severity significant level Support the patient variant viral mutation [DOI] 10.1186/s12888-022-04307-1 PMC 바로가기
New insights into antibody levels against SARS-CoV-2 for healthcare personnel vaccinated with tozinameran (Comirnaty)Article Published on 2022-11-032022-11-15 Journal: PLoS ONE [Category] SARS, 진단, [키워드] activated addition addressed administration Alto Andújar antibody booster dose COVID-19 determine Dilution Elecsy Evolution exhibited Germany Guadalquivir healthcare personnel Healthcare professional humoral IgG in vitro infected patients material Neutralizing antibodies New non-infected pandemic platform Roche SARS-CoV-2 SARS-CoV-2 vaccine second dose serum sample Spike protein subject Thermo Fisher Scientific titer total antibody vaccination Vaccine Volunteer volunteers [DOI] 10.1371/journal.pone.0276968 PMC 바로가기
SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with SofosbuvirArticle Published on 2022-11-032022-11-15 Journal: PLoS Biology [Category] SARS, 치료제, [키워드] accompanied Affect alleviate alteration Antiviral antivirals Brain brain organoid brain organoids cell death cells cellular coronavirus 2 coronavirus disease cortical COVID-19 death determine drug excitatory food infect inhibit SARS-CoV-2 neurological manifestation Neurological symptoms neuronal neurons Newborn pandemic phenotype promote replicate Replication rescued respiratory respiratory illnesses SARS-CoV-2 sofosbuvir Treatment underlie variety WHO World Health Organization [DOI] 10.1371/journal.pbio.3001845 PMC 바로가기
Hyperbaric oxygen for treatment of long COVID-19 syndrome (HOT-LoCO): protocol for a randomised, placebo-controlled, double-blind, phase II clinical trialArticle Published on 2022-11-022022-11-15 Journal: BMJ Open [Category] SARS, 진단, [키워드] approved assessment baseline Blood Cardiology case sery chronic fatigue syndrome chronic inflammation clinical clinical trial cognitive collected common COVID-19 defined domain double-blind dysfunction Effect effective Efficacy endothelial function Ethics evaluate fatigue healthy subject hyperbaric oxygen hypothese immunology IMPROVE Inconclusive independent individual initial institutional review board Long malaise mechanism monitoring board oxygen Oxygen therapy pandemic Patient peer-reviewed performed physical placebo-controlled placebo-controlled clinical trial positive Potential treatment product protocol Quality of life Questionnaires randomised rehabilitation medicine respiratory medicine (see thoracic medicine) secondary endpoint suggested survey Swedish Symptom syndrome the primary endpoint Treatment Trial VASCULAR MEDICINE. [DOI] 10.1136/bmjopen-2022-061870 PMC 바로가기