Trigger – Page 41 – Communicable Diseases Research

Gene Set Signature of Reversal Reaction Type I in Leprosy Patients

나병 환자의 역전 반응 유형 I의 유전자 세트 서명

Research Article

Published on 2013-07-112022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] a major accurate Affect affected Analysis Anti-inflammation anti-inflammatory mediator anti-inflammatory mediators Antigen antigens arachidonic acid Author Blood conducted Critical cured defined Definition diagnosed Diagnosis different differential expression differentially regulated genes Endemic enrolled environmental factor environmental factors evaluated Factor functional Gene genes encoding Genetic genetic background genetic profile Genome healthy individual healthy individuals immune incidence increased risk Inflammatory response Innate immunity leprosy majority mediators metabolism Mycobacterium leprae nerve damage Pathogenesis Patient performed Predictive pro-inflammatory Prospective Study reaction reflect Regulation replicated retrospective Retrospective study reversal reversal reactions RNA sample RNA samples signature Stimulation subsequent subset Transcriptome Trigger triggers Type validation Validity Whole blood
[DOI] 10.1371/journal.pgen.1003624 PMC 바로가기 [Article Type] Research Article

Distinct and Atypical Intrinsic and Extrinsic Cell Death Pathways between Photoreceptor Cell Types upon Specific Ablation of Ranbp2 in Cone Photoreceptors

원추형 광수용체에서 Ranbp2의 특정 제거 시 광수용체 세포 유형 간의 고유하고 비정형적인 고유 및 외인성 세포 사멸 경로

Research Article

Published on 2013-06-202022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] Ablation Activation acute transverse myelitis affecting Apoptosis approaches arise Author base cascade caspase caspase-3 caspase-7 caspase-9 cause Cell cell death clinical manifestations cone cone photoreceptor contribute death degenerate degeneration demise develop Diseases disintegration downstream driving event expression extrinsic Factor followed by found Gene Genes Genetic genetic defect hallmark healthy heterogeneous implicated intrinsic intrinsically manifestation mechanism membrane permeability metalloproteinase modulation molecular mosaic multifunctional protein Mutation Myelitis necrotic neural retina neurodegeneration neurodegenerative neurodegenerative disorders Neuron neurons neuroprotection PARP1 pathway Pathways photoreceptor photoreceptors pleiotropic progression progression of disease promote Protein Ranbp2 rod rod photoreceptor rod photoreceptors rods spatiotemporal Specific Stressor subcellular therapeutic thought transverse myelitis Trigger triggered Tumor Type undergo underlying disease underlying diseases up-regulation
[DOI] 10.1371/journal.pgen.1003555 PMC 바로가기 [Article Type] Research Article

A Mechanism of Gene Amplification Driven by Small DNA Fragments

작은 DNA 조각에 의한 유전자 증폭 메커니즘

Research Article

Published on 2012-12-132022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] amplification amplified amplify annealing Author Cancer cancer cell Cancer cells capture cause Cell chromosomal chromosomal DNA chromosomal region contribute copy number degenerative dependent on detected disorders DNA DNA amplification DNA fragment driving duplication Efficiency elevated event events expression Extracellular Factor favor found fragment Frequency gene amplification Genetic variation genomic homology Human increase independent independent of initiated involved loci mechanism molecular molecular mechanism molecular mechanisms nucleotide nucleotides occur oligonucleotide Organisms Patients with cancer polymorphism Rad1 Rad51 Rad52 regions S. cerevisiae Saccharomyces cerevisiae serum single-stranded stimulate Trigger triggered Variation yeast
[DOI] 10.1371/journal.pgen.1003119 PMC 바로가기 [Article Type] Research Article

Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein

Review

Published on 2012-06-202022-10-28
Journal: Viruses
[Category] Coronavirus,

Principles of Carbon Catabolite Repression in the Rice Blast Fungus: Tps1, Nmr1-3, and a MATE–Family Pump Regulate Glucose Metabolism during Infection

쌀 돌풍 곰팡이의 탄소 이화 작용 억제 원리: Tps1, Nmr1-3 및 MATE-Family 펌프가 감염 중 포도당 대사를 조절합니다

Research Article

Published on 2012-05-032022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] abolishes disease addition Agrobacterium tumefacien Agrobacterium tumefaciens Analysis Author BLAST carbon Carbon catabolite repression carbon metabolism carbon sources Catabolite catabolite repression CCR cell wall cell wall–degrading enzymes component components described disease downstream effective expression filamentous fungi found functional fungal fungal pathogens fungi Genetic genetic regulation Glucose glucose metabolism Glucose-6-phosphate Host identify inactivation Infection infection process inhibitor involved less M. oryzae Magnaporthe MATE protein MATE–family protein Mdt1 mechanism mediators metabolism microbial Mutagenesis Nmr1 Nmr1-3 Nmr1-3 inhibitor proteins nutrient availability organism Pathogenesis pathogenic pathogenicity Pathogens pathway Perturbation physiological principle Protein pump regulate Regulation Regulatory regulatory pathway regulatory pathways repression respond Rice shown sporulation strain sugar target Tps1 transcription factor transcriptional transmembrane Trigger triggers understanding
[DOI] 10.1371/journal.pgen.1002673 PMC 바로가기 [Article Type] Research Article

MK2-Dependent p38b Signalling Protects Drosophila Hindgut Enterocytes against JNK-Induced Apoptosis under Chronic Stress

MK2-의존성 p38b 신호는 만성 스트레스 하에서 JNK 유도 세포자멸사로부터 Drosophila Hindgut Enterocytes를 보호합니다

Research Article

Published on 2011-08-042022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] absence addressed affected antimicrobial peptides Apoptosis atrophy Author branch cascade Cell chronic complex component contribute damage damaged descendants Deterioration Diseases Drosophila Elimination Enterocyte enterocytes epithelial epithelium event form genetic analysis Gut Hindgut homeostasis Impaired induce integrity intestinal Intestinal diseases intestinal epithelium intestinal stem cell Intestinal stem cells JNK kinases leads less manifested pathogen Pathogens pathway peptides peptides) Prevent proliferation PROTECT Protective Protein protein kinase replaced REPLACED BY Replenishment required salt Signal transduction stem cell stem cells Stress Stressor stressors subsequent suppresse Trigger triggers upregulated upstream
[DOI] 10.1371/journal.pgen.1002168 PMC 바로가기 [Article Type] Research Article

SARS-CoV 9b Protein Diffuses into Nucleus, Undergoes Active Crm1 Mediated Nucleocytoplasmic Export and Triggers Apoptosis When Retained in the Nucleus

Research Article

Published on 2011-05-272022-10-28
Journal: PLoS ONE
[Category] Coronavirus,

[키워드] absence Affect Amino acid Apoptosis caspase-3 Cell cellular Critical death Degradation diffuse elevated export found host cell independent induce influence inhibitors interact Interaction Mediated NES NLS nuclear nuclear localization signal nucleus principal Protein SARS-CoV shown transiently transfected Transport Trigger
[DOI] 10.1371/journal.pone.0019436 PMC 바로가기 [Article Type] Research Article

Human rhinovirus infection in young African children with acute wheezing

Research Article

Published on 2011-03-152022-10-28
Journal: BMC Infectious Diseases
[Category] Coronavirus,