Clinical sequelae of the novel coronavirus: does COVID-19 infection predispose patients to cancer?Review Published on 2020-05-272022-10-31 Journal: Future Oncology [Category] COVID-19, MERS, SARS, [키워드] activated association Cancer cancer patient carcinogenic cellular clinical clinical sequelae clinically conducted consequences of infection COVID-19 COVID-19 infection COVID-19 patient Cytokine storm develop elicit events Future global pandemic growth Hypothesis immune system implicated in vitro model Infection innate and adaptive immune response literature review mechanism molecular response mutagenic Novel coronavirus oncology pathway Patient performed Post-infection preclinical studies question SARS-CoV-2 signaling pathway Support tumorigenesis tumors [DOI] 10.2217/fon-2020-0300 PMC 바로가기 [Article Type] Review
Guideline-Based Chinese Herbal Medicine Treatment Plus Standard Care for Severe Coronavirus Disease 2019 (G-CHAMPS): Evidence From ChinaMedicine Published on 2020-05-272022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI accounted age assigned China Chinese Chinese herbal medicine CHM clinical clinically conducted coronavirus disease COVID-19 Critical death died Effect guideline Herbal hospitalized patient information Medicine Mild moderate National national guideline participant Patient pilot study Primary outcome progressed provided Randomized Randomized controlled trial randomized, controlled trial Randomly receive screened severe COVID-19 severe COVID-19 disease severity Stage Standard standard care standard care group the disease the patient treated Treatment Trial women Wuhan, China [DOI] 10.3389/fmed.2020.00256 PMC 바로가기 [Article Type] Medicine
Clinical analysis of sinus bradycardia in patients with severe COVID-19 pneumoniaResearch Letter Published on 2020-05-262022-11-01 Journal: Critical Care [Category] Coronavirus, MERS, SARS, [키워드] ACE2 Analysis bradycardia clinical clinical manifestation COVID-19 Patient Severe COVID-19 pneumonia severe pneumonia sinus bradycardia [DOI] 10.1186/s13054-020-02933-3 PMC 바로가기 [Article Type] Research Letter
Reducing the Fatality Rate of COVID-19 by Applying Clinical Insights From Immuno-Oncology and Lung TransplantationPharmacology Published on 2020-05-262022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] 2019-nCoV accelerated acute lung injury acute respiratory distress syndrome Algorithm Applying ARDS Arm cause clinical clinical development clinical trial Combination COVID-19 Cytokine release syndrome effective effective strategy Enrollment Fatality rate identify inflammatory process insight lung lung transplantation multi-organ failure Pneumonia Rate reducing Safe systemic capillary leak Treatment Trial [DOI] 10.3389/fphar.2020.00796 PMC 바로가기 [Article Type] Pharmacology
Scope, quality, and inclusivity of clinical guidelines produced early in the covid-19 pandemic: rapid reviewResearch Published on 2020-05-262022-10-28 Journal: The BMJ [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome antiviral drugs applicability applied appraisal children clinical clinical guideline Collection core coronavirus disease criteria database domain early stage eligible Evidence example exclusion for inclusion global health Government group guideline Health Inclusion Index Medicus International ISARIC limit management MERS methodological Middle East National objective Older OVID pandemic populations pregnant women produced public health emergency Quality Rapid recommendation Result searched syndrome Web of Science were excluded WHO [DOI] 10.1136/bmj.m1936 PMC 바로가기 [Article Type] Research
Available Evidence and Ongoing Clinical Trials of Remdesivir: Could It Be a Promising Therapeutic Option for COVID-19?Pharmacology Published on 2020-05-262022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] acute respiratory syndrome addition antiviral activity approved clinical Clinical improvement clinical trial conducted Coronavirus-2 COVID-19 double blind double-blind Ebola Efficacy Evidence exhibited faster global public health globe GS-5734 in vitro in vitro activity in vivo Infection MERS-CoV Novel coronavirus open label option Phase 3 Placebo placebo controlled trial Prevent preventive measure Randomized RdRP Remdesivir RNA RNA polymerase SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 strain Science severe COVID-19 patient statistically significant Strains therapeutic option therapy treat Trial Vaccine WHO Solidarity trial Wuhan, China [DOI] 10.3389/fphar.2020.00791 PMC 바로가기 [Article Type] Pharmacology
Core Outcome Set for Clinical Trials of COVID-19 Based on Traditional Chinese and Western MedicinePharmacology Published on 2020-05-252022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] antibody Blood blood gas analysis Blood oxygen saturation C-reactive protein Chinese clinical Clinical efficacy Clinical outcome clinical symptom clinical trial clinical trials conducted Consensus core Core outcome set COVID-19 DelPhi development disease eligible etiology heterogeneity IMPROVE Inflammatory limitation Lymphocytes mechanical ventilation Medicine methodology mild-to-moderate disease Nurses outcome oxygen pandemic PaO2/FiO2 ratio parameter participated Patient Pneumonia Severity Index Prevalence progression protocol questionnaire Research Respiratory outcome Result SARS-CoV-2 severe disease Study protocol Symptom systematic review TCM temperature Traditional Traditional Chinese medicine Viral load virus vital sign Western medicine [DOI] 10.3389/fphar.2020.00781 PMC 바로가기 [Article Type] Pharmacology
Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysisResearch Published on 2020-05-242022-10-30 Journal: Journal of Intensive Care [Category] COVID-19, [키워드] acute respiratory distress Admission Affect affected age Analysis ARDS article association calculate Care Characteristics clinical Comorbidity Comprehensive conducted Confidence intervals COPD coronavirus coronavirus disease COVID-19 databases Diabetes Mellitus diagnosed with COVID-19 dichotomous variable died Gender Google Scholar heterogeneity hypertension ICU ICU care information intensive care inverse laboratory biomarker likelihood Lymphocyte count lymphopenia marker mean difference Meta-analysis meta-regression Mortality objective Odds ratio outcome pandemic Patient patients with COVID-19 predict ProQuest random-effect resource Respiratory Support Result SARS-CoV-2 severe COVID-19 severity severity of COVID-19 smoking standard deviations syndrome systematic literature search systematic review was performed was used were used [DOI] 10.1186/s40560-020-00453-4 PMC 바로가기 [Article Type] Research
COVID-19: The Case of Three Patients with the Same Diagnosis but Different Clinical and Laboratory FeaturesCase Report Published on 2020-05-242022-10-31 Journal: Case Reports in Medicine [Category] COVID-19, [키워드] affected Blood cells case sery cause Central nervous system clinical cough COVID-19 develop diarrhea disease Factor Fever Hospitalized include liver other organ pandemic pathogenicity Patient respiratory tract responsible RNA virus SARS-CoV-2 Shortness of breath Symptom with COVID-19 [DOI] 10.1155/2020/9185041 PMC 바로가기 [Article Type] Case Report
An Atypical Presentation of Acute Pulmonary Embolism With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) PneumoniaInternal Medicine Published on 2020-05-232022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome Atypical clinical clinical suspicion coronavirus coronavirus 2 COVID-19 diagnostic Embolism Gastrointestinal symptom highlight Infection Patient patient with SARS-CoV-2 patients presentation presenting pulmonary Pulmonary embolism respiratory SARS-CoV-2 severity supported Symptoms Therapeutic approach Thromboembolism unique [DOI] 10.7759/cureus.8249 PMC 바로가기 [Article Type] Internal Medicine