Single-Point Mutations in the N Gene of SARS-CoV-2 Adversely Impact Detection by a Commercial Dual Target Diagnostic AssaySARS-CoV-2의 N 유전자에 있는 단일점 돌연변이는 상업용 이중 표적 진단 분석에 의한 역효과 검출Research Article Published on 2021-11-172022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 진단, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 acute SARS-CoV-2 infection amplicons amplification amplified assays binding Cepheid Cepheid Xpert coronavirus Critical detection determine Diagnosis diagnostic diagnostic assay diagnostic tests early diagnosis eight FIVE gene target Genetic genomic gold gold standard highlight Impact knowledge Mutation N gene nucleic acid amplification tests occur pandemic patients PCR product point mutations position Rapid diagnostic test Real-time PCR Region reported respiratory responsible SARS-CoV-2 SARS-CoV-2 genome sequenced Sequencing severe acute respiratory syndrome Coronavirus single-point mutation single-point mutations target the SARS-CoV-2 genome whole genome whole genomes [DOI] 10.1128/Spectrum.01494-21 PMC 바로가기 [Article Type] Research Article
Extended minimally invasive autopsy: Technical improvements for the investigation of cardiopulmonary events in COVID-19확장된 최소 침습적 부검: COVID-19의 심폐 사건 조사를 위한 기술 개선Original Article Published on 2021-11-172022-09-10 Journal: Clinics [Category] MERS, SARS, 치료기술, [키워드] Accuracy alternative Autopsy biopsies can be used Cardiopulmonary contagious COVID-19 died Diseases eight evaluated event events Evidence Extended feasible flexible heart human diseases improvement Infectious diseases invasive limitation Lungs Minimally Invasive Autopsy Myocardial infarction organ pandemic pathophysiology Patient Post-mortem post-mortem biopsy sampling technique Thoracic Thromboembolism tissue tissue sample Ultrasound vessels was performed [DOI] 10.6061/clinics/2021/e3543 PMC 바로가기 [Article Type] Original Article
Household Transmission of SARS-CoV-2: A Prospective Longitudinal Study Showing Higher Viral Load and Increased Transmissibility of the Alpha Variant Compared to Previous StrainsArticle Published on 2021-11-172022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Adults Alpha variant Asymptomatic B.1.1.7 biological sample concern confirmed COVID-19 case Contact contagious COVID-19 ddPCR digital PCR Effectiveness eight household household contact household contacts household transmission Increased load longitudinal occurred participant Prospective Questionnaires real-time RT-PCR recruited reduce reduced Risk factors risk of transmission SAR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission secondary attack rate significantly higher strain Transmission Vaccine variant variants Viral load virus viruses were used Whole genome sequencing [DOI] 10.3390/microorganisms9112371 PMC 바로가기 [Article Type] Article
Prevalence of SARS-CoV-2 antibodies in hemodialysis patients in Senegal: a multicenter cross-sectional study세네갈의 혈액 투석 환자에서 SARS-COV-2 항체의 유병률 : 다기관 횡단면 연구Multicenter Study Published on 2021-11-172022-09-01 Journal: BMC Nephrology [Category] MERS, SARS, 진단, [키워드] Abbott African Analysis antibody Architect Asymptomatic disease biological parameter biological parameters blood sample Blood samples clinical clinical symptom Clinical symptoms collected conducted Contact contact with continent COVID-19 cross-sectional cross-sectional survey dialysis eight General population group Hemodialysis Infection information knowledge lethality rate lowest majority medical records multicenter Multivariate analysis nasal swab objective Patient patients patients with SARS-CoV-2 PCR-confirmed performed population density proportion Randomly Region reported Result SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 seroprevalence seeking selected Senegal seroconvert seropositive Seroprevalence Stata Statistical tests Symptom tested the disease Variability [DOI] 10.1186/s12882-021-02582-w PMC 바로가기 [Article Type] Multicenter Study
SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissuesSARS-CoV-2 감수성과 COVID-19 질병 중증도는 다양한 조직에서 유전자 발현에 영향을 미치는 유전적 변이와 관련이 있습니다Article Published on 2021-11-162022-09-11 Journal: Cell Reports [Category] SARS, 변종, 유전자 메커니즘, [키워드] affecting association Brain causal SNP Colocalization COVID-19 COVID-19 disease COVID-19 disease severity digestive system disease severity disease severity of COVID-19 eight eQTL eQTL. eQTLs expression expression quantitative trait loci Factors Gene Expression gene expression level Genetic genetic factors Genetic variant Genome Genome-wide association study genomic genomic loci GWAS heart identify immune system individual loci lung muscle Quantitative SARS-CoV-2 SARS-CoV-2 susceptibility skin SNP Symptom tissue Variability variant variants variety variety of tissue [DOI] 10.1016/j.celrep.2021.110020 PMC 바로가기 [Article Type] Article
Dynamic Profile of Prognostic Hematologic Indicators in Patient Under Intensive Care for COVID-19 Disease: A One-Year Study at a Tertiary Care Centre in South IndiaInternal Medicine Published on 2021-11-152022-10-31 Journal: Cureus [Category] COVID-19, [키워드] absolute values acute respiratory syndrome Admission adverse outcome Analysis baseline characteristics Blood blood cell bloodstream both group both sexes calculated caused change comparable conducted coronavirus COVID 19 COVID-19 COVID-19 disease cut-off cytokine dynamic eight help hospitalized patient ICU ICU care Indicator initial intensive care Laboratory lymphocyte Lymphocytes lymphopenia Mann-Whitney test material medical intensive care unit (micu) Migration Mortality neutrophil neutrophil to lymphocyte ratio (nlr) neutrophilia Neutrophils NLR non-survivor Non-survivors P-value pathology Patient patients hospitalized percentage Platelet platelet to lymphocyte ratio (plr) Pneumonia predict predicted profile Prognosis reflected Release required Result retrieved severity severity and prognosis significantly lower south India survived survivor Tertiary the disease those who survived Variation was done with COVID-19 worsening [DOI] 10.7759/cureus.19585 PMC 바로가기 [Article Type] Internal Medicine
Evaluation of a bioaerosol sampler for indoor environmental surveillance of Severe Acute Respiratory Syndrome Coronavirus 2중증 급성 호흡기 증후군의 실내 환경 감시를위한 바이오 에로솔 샘플러 평가 코로나 바이러스 2Research Article Published on 2021-11-152022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료기술, 치료제, [키워드] ACh ACM acute respiratory syndrome coronavirus Administered aerosol capture Concentration contagious coronavirus coronavirus 2 effective eight experiments Genome greater highest hour impacted impaction increasingly individual investigated less life media nucleic acid respiratory risk room air SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread Support Surveillance Swab utility Vaccine [DOI] 10.1371/journal.pone.0257689 PMC 바로가기 [Article Type] Research Article
Detection of Fake News Text Classification on COVID-19 Using Deep Learning Approaches딥 러닝 접근 방식을 사용하여 COVID-19에 대한 가짜 뉴스 텍스트 분류 감지Research Article Published on 2021-11-152022-09-11 Journal: Computational and Mathematical Methods in Medicine [Category] MERS, SARS, 치료기술, [키워드] Algorithm Analysis applied approach Bayesian classification CNN Confusion confusion matrix COVID-19 dataset Decision tree deep deep learning detection eight evaluated fake news help high accuracy inverse document frequency learning Logistic regression machine-learning measure media New predict provided Python random Random forest recommendation Research researcher researchers social media Support support vector machine term frequency tested text tokenization true positive Weighting [DOI] 10.1155/2021/5514220 PMC 바로가기 [Article Type] Research Article
Gross hematuria after SARS-CoV-2 vaccination: questionnaire survey in JapanOriginal Article Published on 2021-11-132022-10-31 Journal: Clinical and experimental nephrology [Category] COVID-19, [키워드] clinical feature conducted Coronavirus 2019 correlation COVID-19 COVID-19 vaccination diagnosed eight FIVE gross hematuria healthcare worker Hematuria IgA nephropathy immunoglobulin A Japan Japanese mRNA vaccination mRNA vaccine Nephrology nephropathy Occurrence Patient progressed progression Proteinuria protocol questionnaire receiving recent renal reported Result SARS-CoV-2 SARS-CoV-2 vaccination serum creatinine Seven severe renal dysfunction Society supplementary material vaccination was performed [DOI] 10.1007/s10157-021-02157-x PMC 바로가기 [Article Type] Original Article
First Case of Erythema Nodosum Associated With Pfizer VaccineEmergency Medicine Published on 2021-11-132022-10-31 Journal: Cureus [Category] COVID-19, [키워드] abnormality absence Chest coronavirus disease COVID-19 cutaneous side effects eight Erythema erythema nodosum first dose healthy immune reaction Laboratory laboratory investigation nodule Pfizer receiving resolved Vaccine Vaccines [DOI] 10.7759/cureus.19529 PMC 바로가기 [Article Type] Emergency Medicine