Intensive – Page 42 – Communicable Diseases Research

Development of early warning and rapid response system for patients with novel coronavirus pneumonia (COVID-19) A research protocol

3900

Published on 2020-08-212022-10-30
Journal: Medicine [Category] COVID-19, MERS,

[키워드] addition Adult patient build caused Clinical deterioration cohort study contagious Coronavirus disease 2019 COVID-19 COVID-19 patients Critical Critical care Critically ill Critically ill patient detect deteriorate Deterioration determine development diagnosed with COVID-19 disease disease severity driven by early warning example excluded hospital Hypothesis ICU immunosuppression state implementation include increase increased risk Intensive intensive care interval Intervention lactating medical resource mortality rate Novel coronavirus Nurses outcome Patient patient self-reporting patients Physicians Pneumonia pregnant Primary outcome problems proportion prospective cohort study provide public health rapid response recommendations recruited required Research Research protocol risk secondary significantly transfer Treatment Vaccine
[DOI] 10.1097/MD.0000000000021874 PMC 바로가기 [Article Type] 3900

Ledipasvir plus sofosbuvir in pregnant women with hepatitis C virus infection: a phase 1 pharmacokinetic study

C형 간염 바이러스 감염 임산부에 대한 레디파스비르 + 소포스부비르: 1상 약동학 연구

Article

Published on 2020-08-132022-09-06
Journal: The Lancet. Microbe [Category] Communicable Disease,

[키워드] All participants Alter analysed AUC changes in Child child health clinically concentration–time curve Course development dosing interval during pregnancy effective enrolled Epidemic finding funding genotype 1 geometric geometric mean geometric mean ratio gestation HCV Hepatitis hepatitis C hepatitis C virus Human Human Development Infants Infection Intensive Intervention ledipasvir Magee-Womens Hospital nine Open-label opioid parameter participant participated pharmacokinetic pharmacokinetics Phase 1 phase 1 study Phase 2 Physiological changes Pittsburgh Pregnancy pregnant pregnant women primary analysis Primary outcome reduce Registered Safe screened sofosbuvir sofosbuvir) Transmission treat Trial USA virus was used women
[DOI] 10.1016/S2666-5247(20)30062-8 PMC 바로가기 [Article Type] Article

Single-cell landscape of immunological responses in patients with COVID-19

Research

Published on 2020-08-122022-10-05
Journal: Nature Immunology [Category] SARS, 치료기술, 치료법,

Repetitive Intermittent Hyperglycemia Drives the M1 Polarization and Inflammatory Responses in THP-1 Macrophages Through the Mechanism Involving the TLR4-IRF5 Pathway

Article

Published on 2020-08-122022-10-31
Journal: Cells [Category] COVID-19,

[키워드] adipose Alter blood glucose CD11c change Chemokine receptor Complication complications condition confocal microscopy correlated Critical downstream drive ELISA expression flow cytometry fluctuation Gene Expression Glucose Glucose fluctuation glucose fluctuations glycemic control hemoglobin homeostatic hyperglycemia hypoglycemia IL-1β IL-6 independent risk factor individuals Inflammation Inflammatory Inflammatory marker Inflammatory response insulin resistance Intensive interferon regulatory factor Intermittent Involving IRF5 Macrophage macrophages marker matrix metalloproteinase mechanism metabolic inflammation monocyte monocytes/macrophages motif Necrosis occur pathway Patient patients polarization promote Protein qRT-PCR repetitive intermittent hyperglycemia response RNA siRNA T2D therapy THP-1 tissue sample TLR4 TNF-α Toll-like receptor Transcription type-2 diabete type-2 diabetes western blotting
[DOI] 10.3390/cells9081892 PMC 바로가기 [Article Type] Article

Status of occupational protection in the COVID-19 Fangcang Shelter Hospital in Wuhan, China

Research Article

Published on 2020-08-122022-10-31
Journal: Emerging Microbes & Infections [Category] COVID-19, MERS, SARS,

[키워드] Fangcang Shelter Hospital activity Analysis caused China competent composed COVID-19 COVID-19 outbreak HCW Health-care workers Intensive Lake measure National occupational protection participant Personal protective equipment PPE SARS-CoV-2 SARS-CoV-2 RNA staff status wearing mask Wuhan, China
[DOI] 10.1080/22221751.2020.1803145 PMC 바로가기 [Article Type] Research Article

Impact of diabetes on COVID-19-related in-hospital mortality: a retrospective study from Northern Italy

Original Article

Published on 2020-08-102022-10-30
Journal: Journal of Endocrinological Investigation [Category] COVID-19, MERS, SARS,

[키워드] age C-reactive protein cardiovascular disease chronic obstructive collected comorbid condition conducted confounding variables coronavirus COVID-19 death diabete diabetes evaluate evaluate the effect hospital Hospitalized hypertension Impact In-hospital in-hospital mortality Intensive Italy Laboratory lactic dehydrogenase Logistic regression lombardy male medical record Mortality multivariable model neoplasm occurred Older age Patient patients pulmonary disease relative Result retrospective Retrospective study SARS-CoV-2 single center single-center study Surveillance the patient was performed with COVID-19
[DOI] 10.1007/s40618-020-01382-7 PMC 바로가기 [Article Type] Original Article

Considerations for Return to Exercise Following Mild-to-Moderate COVID-19 in the Recreational Athlete

Response to COVID-19 / Review Article

Published on 2020-08-102022-10-31
Journal: HSS Journal [Category] COVID-19,

[키워드] activity Affect athlete Care clinical disease clinician COVID-19 COVID-19 case COVID-19 pandemic disease expression exercise gastrointestinal systems hematologic include Intensive less literature review majority Mild Mild-to-moderate Moderate COVID-19 morbidity morbidity and mortality Musculoskeletal offer Patient recommendation recreational athlete return seeking severe symptom supplementary material supportive care Symptom treated
[DOI] 10.1007/s11420-020-09777-1 PMC 바로가기 [Article Type] Response to COVID-19 / Review Article

The Unrecognized Threat of Secondary Bacterial Infections with COVID-19

Commentary

Published on 2020-08-072022-10-29
Journal: mBio [Category] COVID-19, MERS,

Early experience with universal preprocedural testing for SARS-CoV-2 in a relatively low-prevalence area

상대적으로 유병률이 낮은 지역에서 SARS-CoV-2에 대한 보편적인 절차 전 테스트에 대한 초기 경험

Multicenter Study

Published on 2020-08-032022-09-12
Journal: Infection Control and Hospital Epidemiology [Category] MERS, 진단,

Conscious prone positioning during non-invasive ventilation in COVID-19 patients: experience from a single centre

Brief Report

Published on 2020-07-312022-10-31
Journal: F1000Research [Category] COVID-19, MERS, SARS,