Comparative Assessment of Sera from Individuals after S-Gene RNA-Based SARS-CoV-2 Vaccination with Spike-Protein-Based and Nucleocapsid-Based Serological AssaysCommunication Published on 2021-03-032022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Anti-spike antibody assessment Breakthrough infection Comparative COVID-19 detectable different time point Effect epitope Euroimmun expected first dose humoral IgA IgG IgM individual natural infection nucleocapsid positive Protein RNA vaccine SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein second dose serological serological response serology serum sample specificity Spike protein Surveillance the vaccine vaccination vaccination against COVID-19 vaccinee while [DOI] 10.3390/diagnostics11030426 PMC 바로가기 [Article Type] Communication
The Conundrum of Giglio Island: Unraveling the dynamics of an apparent resistance to COVID-19 – A descriptive studyResearch Article Published on 2021-03-022022-10-31 Journal: Computational and Structural Biotechnology Journal [Category] COVID-19, [키워드] 2019-nCoV Abstract acid Asymptomatic asymptomatic infection baseline carried Cohort conducted COVID-19 cross-reactivity develop Endemic female Giglio Island hypotheses IgM island Italy Local male median age molecular analysis NAAT objective occurred positive positive result Prevalence protective factor Rapid test Result risk RT-qPCR Saliva SARS-CoV-2 SARS-CoV-2 seroprevalence serologic serological Serological testing subject Symptom Test viruses was performed [DOI] 10.1016/j.csbj.2021.02.008 PMC 바로가기 [Article Type] Research Article
Performance of a Point of Care Test for Detecting IgM and IgG Antibodies Against SARS-CoV-2 and Seroprevalence in Blood Donors and Health Care Workers in PanamaMedicine Published on 2021-03-022022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval 95%CI Accuracy acute respiratory syndrome Against Analysis analyzed antibody Biomarker blood donor clinical symptom community transmission Contact tracing contribute coronavirus coronavirus disease correlation COVID-19 COVID-19 patients determine Diagnosis diagnostic donors Efficacy estimate evaluate Health care worker health care workers healthy healthy blood donors highest hospitalized COVID-19 patient identify IgG antibody IgM and IgG immunochromatographic assay IMPROVE indicate lateral flow molecular test novel Panama pandemic participant performance Point positive positive RT-PCR post-symptom onset PSO reached recruited SARS-CoV-2 sensitivity serological serology Seroprevalence serum sample serum samples significantly specific IgM study participant Surveillance Symptom Test Vaccine virus worker [DOI] 10.3389/fmed.2021.616106 PMC 바로가기 [Article Type] Medicine
Ferritin is associated with the severity of lung involvement but not with worse prognosis in patients with COVID-19: data from two Italian COVID-19 units페리틴은 폐 침범의 심각성과 관련이 있지만 COVID-19 환자의 더 나쁜 예후와는 관련이 없습니다: 2개의 이탈리아 COVID-19 유닛의 데이터Clinical Trial Published on 2021-03-012022-08-13 Journal: Scientific Reports [Category] SARS, 바이오마커, 임상, 진단, 치료기술, [키워드] 95% CI Abruzzo Admission age and gender Biomarker Care clinical clinical decision Clinical sign Clinical signs complex Computed tomography conducted coronavirus coronavirus 2019 disease Course covariate covariates COVID-19 CT scan death Deceased demonstrated discharged disease disease severity enrolled evaluated feature female ferritin ferritin level ferritin levels help heterogeneous hospital hospitalized patient hospitalized patients identify investigated Italian Italy Logistic regression analysis lung abnormalities lung abnormality lung involvement lymph node enlargement males median age mediastinal lymph node mediastinal lymph node enlargement no differences occurred outcome outcomes pathophysiology Patient patients patients with COVID-19 Prognosis prognosis of patient pulmonary involvement pulmonary lobe pulmonary lobes regression analysis retrospective SARS-CoV-2 SARS-COV-2 infection septal thickening serological severe pulmonary involvement severity Therapeutic approach therapeutic approaches unit worse prognosis [DOI] 10.1038/s41598-021-83831-8 PMC 바로가기 [Article Type] Clinical Trial
Clinical applications of detecting IgG, IgM or IgA antibody for the diagnosis of COVID-19: A meta-analysis and systematic review코로나19 진단을 위한 IgG, IgM, IgA 항체 검출의 임상적용: 메타분석 및 체계적 고찰Meta-Analysis Published on 2021-03-012022-09-11 Journal: International Journal of Infectious Diseases [Category] SARS, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome analysed antibody Antibody test Antibody testing antibody tests Antigen chemiluminescence immunoassay clinical clinics conducted coronavirus disease Coronavirus disease 2019 Coronavirus-2 Course COVID-19 Critical diagnose Diagnosis diagnosis of COVID-19 diagnostic Diagnostic accuracy Diagnostic method disease disease course IgA IgG IgM immunoassay increasingly infected patient infected patients information Meta-analysis offer pandemic patients with COVID-19 Prevent quarantine ranged respiratory S protein SARS-CoV-2 sensitivity serological Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus specificity Spread Support symptom onset systematic review Test test results the disease [DOI] 10.1016/j.ijid.2021.01.016 PMC 바로가기 [Article Type] Meta-Analysis
Endoscopy infection control strategy during the COVID-19 pandemic: experience from a tertiary cancer center in BrazilOriginal Article Published on 2021-03-012022-10-31 Journal: Clinics [Category] COVID-19, SARS, [키워드] acute respiratory syndrome affected Brazil Cancer Cancer center Care carried Clinical data collected data Colonoscopy coronavirus coronavirus disease COVID-19 COVID-19 outbreak Diagnosis diagnosis of COVID-19 digestive Effect effective endoscopy equipment evaluate HCW HCWs healthcare worker Infection infection control infection rate maintain measure medical services mitigate Nurse pandemic Pandemics Patient patients performed PPE Protective reduction Retrospective analysis risk SARS-CoV-2 SARS-CoV-2 test serological state Strategy tissue Transmission Viral transmission were infected [DOI] 10.6061/clinics/2021/e2280 PMC 바로가기 [Article Type] Original Article
The Sheba Medical Center healthcare workers’ children’s school: can we open schools safely?시바의료원 의료종사자 아동학교, 안전하게 개학할 수 있을까?Article Published on 2021-03-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 alternative school Blood center children collected conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-sectional cross-sectional study determined by disease Epidemiology Evidence evidence of Families groups HCW HCWs health-care Health-care workers healthcare worker IgA IgG Infection lifted lockdown nasopharyngeal National no evidence of not significantly different number of children oropharyngeal swab outbreak parent PCR positive recruited remained reported symptom respiratory RT-PCR SARS-CoV-2 School screened serological Serological tests serology severe acute respiratory syndrome Coronavirus Surveillance Symptom tested titres Transmission was collected [DOI] 10.1016/j.cmi.2020.11.030 PMC 바로가기 [Article Type] Article
Impact of chemotherapy on lymphocytes and serological memory in recovered COVID-19 patients with acute leukemiaResearch Paper Published on 2021-03-012022-10-31 Journal: Journal of Cancer [Category] COVID-19, [키워드] affected analyzed antibody B cell B cells change changes in characterized Chemotherapy COVID-19 COVID-19 pandemic COVID-19 recovered patient enrolled flow cytometry healthy Immune cell immune memory Immunity Impact impair individuals Intensive leukemia Level lymphocyte Lymphocytes memory memory B cells MOST NK cell Patient patients Peripheral blood raised recovered COVID-19 patient recovering from COVID-19 reported SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgM serological Serum level significantly stability susceptible T cell T cells the SARS-CoV-2 three group Treatment two group uninfected [DOI] 10.7150/jca.53863 PMC 바로가기 [Article Type] Research Paper
Breadth and function of antibody response to acute SARS-CoV-2 infection in humans인간의 급성 SARS-CoV-2 감염에 대한 항체 반응의 범위와 기능Research Article Published on 2021-02-262022-08-13 Journal: PLoS Pathogens [Category] Biochemistry, MERS, 진단, 치료법, [키워드] ACE2 ACE2-blocking response acute SARS-CoV-2 infection acute viral infection analysed anti-non-RBD S1 Anti-RBD antibodies Anti-RBD antibody Anti-RBD MAb Anti-RBD MAbs anti-receptor-binding domain anti-S2 Anti-spike anti-spike MAbs antibody Antibody Response Antibody responses Antibody-mediated immunity average Betacoronavirus binding blockade blocked clone Clusters combinations Complete COVID-19 outbreak COVID-19 patient cross-react elicited epitope Epitopes expansion Fever FIVE glycoprotein Health Human human coronavirus human coronavirus OC43 humans Humoral response IgG Immunity independent assays mAbs memory B cell memory B cells monoclonal antibody neutralise neutralising Neutralising activity Neutralising Antibodies neutralising antibody neutralising antibody response non-overlapping epitope non-overlapping epitopes non-RBD S1 nucleocapsid offer outbreak Patient peripheral plasmablast response plasmablast plasmablast response plasmablast responses potent Prolonged fever Prophylactic RBD reactive Receptor-binding domain recovered patient Region responses SARS-CoV-2 SARS-COV-2 infection separate cluster sera serological Serological and plasmablast responses serology somatic mutations spike glycoprotein subset tested the RBD the receptor-binding domain therapeutic agent therapeutic agents titre Viral viral infection Virus spike wild-type SARS-CoV-2 [DOI] 10.1371/journal.ppat.1009352 PMC 바로가기 [Article Type] Research Article
Incidence of COVID-19 in patients under chronic treatment with hydroxychloroquineObservational Study Published on 2021-02-262022-10-05 Journal: Medicina clínica [Category] 임상, [키워드] absence appear clinical variable Comorbidity coronavirus COVID-19 COVID-19 in patient Diagnosis died dose Health Hidroxicloroquina Hospital admission Hydroxychloroquine incidence Incidencia Infection maculopathy multicenter participant pathology Patient polymerase chain recruitment required retrospective selected serological significantly Tratamiento Treatment use of hydroxychloroquine was related were recorded [DOI] 10.1016/j.medcli.2020.10.006 PMC 바로가기 [Article Type] Observational Study