Phylogenetic distribution and predominant genotype of the avian infectious bronchitis virus in China during 2008-2009Research Published on 2011-04-222022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] age Amino acid amino acids sequence amplified Analysis bronchitis caused Characteristics China circulating cleavage site coding region death different distribution Gene Genotype homology IBV indicated infectious Infectious Bronchitis Virus isolate molecular MOST nucleotide Outbreaks pandemic predominant Prevalence Protein Result RT-PCR S1 protein sequenced strain Strains suggested trials Vaccine virus [DOI] 10.1186/1743-422X-8-184 PMC 바로가기 [Article Type] Research
Human rhinovirus infection in young African children with acute wheezingResearch Article Published on 2011-03-152022-10-28 Journal: BMC Infectious Diseases [Category] Coronavirus, [키워드] African age analysed Analysis caused Characteristics children circulating clinical disease Culture deaths detect detected determine enrolled Fisher group hospital Hospitalized HRV Human In-hospital increasingly Infection information intensive care métapneumovirus Mild moderate monoclonal antibody morbidity MOST nasal swab occurred other respiratory virus PCR-based assays presenting presenting symptom respiratory virus Result reverse transcription PCR rhinovirus rhinovirus South therapy to screen Treatment Trigger viral infection was performed was used wheezing [DOI] 10.1186/1471-2334-11-65 PMC 바로가기 [Article Type] Research Article
The relationship between antibody status to bovine corona virus and bovine respiratory syncytial virus and disease incidence, reproduction and herd characteristics in dairy herdsResearch Published on 2010-06-042022-10-28 Journal: Acta Veterinaria Scandinavica [Category] Coronavirus, Fulltext, MERS, [키워드] Affect analysed analyzed antibody antibody status association BCV both virus bovine Characteristics circulating collected compared cow disease incidence enzyme-linked immunosorbent assays evaluate the effect FIVE Health Herd Immunoglobulin Infection Infection transmission information Local mapped median negative parameter positive primiparous proportion reproductive respiratory syncytial virus Result somatic cell count Spread statistically significant Swedish Transmission virus [DOI] 10.1186/1751-0147-52-37 PMC 바로가기 [Article Type] Research
Analysis of Intraviral Protein-Protein Interactions of the SARS Coronavirus ORFeomeResearch Article Published on 2007-05-232022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] acute respiratory syndrome Analysis Characteristics cloned complex coronavirus deleted different displaying expected expression function functional Genome genome-wide analysis growth in vitro interact Interaction interactions mammalian cells non-structural protein Nsp12 nsp13 nsp14 NSP2 Nsp9 open reading frames ORF Orf9b ORFeome pathogenicity performed positive predicted Protein protein interaction Proteins proteome Replication SARS-CoV shown stability tested Vero cells Viral proteins viral replication virus [DOI] 10.1371/journal.pone.0000459 PMC 바로가기 [Article Type] Research Article
SARS-CoV replication and pathogenesis in an in vitro model of the human conducting airway epitheliumArticle Published on 2007-04-232022-11-01 Journal: Virus research [Category] Coronavirus, MERS, [키워드] addition airway airway epithelial cells airway epithelium Antisera apical surface Atypical Calu-3 Calu-3 cell Cell cells cellular Characteristics ciliated ciliated cell consequence coronavirus coronavirus pathogenesis Coronavirus replication Culture cultures detected develop did not reduce dry cough efficient enzyme Epidemics epithelial epithelial cell epithelial cell line Experimental result feature Fever fluorescent Frame GFP hACE2 HAE Human human airway epithelia human airway epithelial Human airway epithelium human lung human pathogen in vitro in vitro model in vivo Infection inoculated insertion late stage log Lower respiratory tract lung lung epithelial mechanism Morphological new strain onset of symptoms ORF Pathogenesis pathology physiological Pneumonia Post-infection primary cell progeny virion Protein provide reached receptor reduced replicate replicated Replication reported reservoir respiratory virus resulting SARS Coronavirus SARS-CoV SARS-CoV GFP SARS-CoV infection Support susceptible target tight junction Trachea Vero E6 viral infection viral replication viral titer virus virus wild type zoonotic [DOI] 10.1016/j.virusres.2007.03.013 PMC 바로가기 [Article Type] Article
Molecular Epidemiology of SARS-associated Coronavirus, BeijingResearch Published on 2005-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] amplified amplified products Beijing Characteristics clinical sample Cluster collected coronavirus different dominant Epidemics geographic location Guangdong Host immune pressure isolate loci molecular Molecular epidemiology motif Mutation nucleotide Patient patients reported RT-PCR RT-PCR, research SARS-CoV selective sequence Sequencing Severe acute respiratory syndrome single nucleotide variation SNV SNVs to define Variation viral adaptation were used [DOI] 10.3201/eid1109.040773 PMC 바로가기 [Article Type] Research
Molecular analysis of S gene of spike glycoprotein of winter dysentery bovine coronavirus circulated in Korea during 2002–2003Short Communication Published on 2004-08-262022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] Amino acid Analysis analyzed avirulent Bovine coronavirus Characteristics compared conducted coronavirus strain country diarrhea French Genetic Genetic characteristics glycoprotein homologous isolate Korean molecular analysis nucleotide Phylogenetic analysis related S gene S glycoprotein sequence significantly spike glycoprotein strain Strains the S1 subunit [DOI] 10.1016/j.virusres.2004.07.003 PMC 바로가기 [Article Type] Short Communication
Coronaviridae and SARS-associated Coronavirus Strain HSR1Research Published on 2004-03-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] 2003 addition affected Analysis biologic Cell cell membrane Characteristics Coronaviridae coronavirus CoV determined Evidence Features form full-length generate Genetic genomic hotel Infected Infection inhibited Isolation Italian Italy molecular New coronavirus outbreak Patient Plaque assay Real-time PCR required SARS-coronavirus SARS-CoV sequence specimen sputum strain TaqMan the patient Vero Cell Vesicle viral genome viral genome sequence virion [DOI] 10.3201/eid1003.030683 PMC 바로가기 [Article Type] Research
Molecular analysis of the S1 subunit of the spike glycoprotein of respiratory and enteric bovine coronavirus isolatesArticle Published on 2002-01-302022-11-01 Journal: Virus research [Category] Coronavirus, [키워드] Allelic variation alteration Amino acid amino acid change amino acid substitution Analysis analyzed antigenic Bovine coronavirus Characteristics classical cleavage site Clustering compared diarrhea different Genetic group hydrophobicity isolate isolates led to nucleotide Phylogenetic analysis polymorphism predicted Probability Protein residue Respiratory and enteric BoCV S glycoprotein S1 subunit secondary structure sequence Sequencing significant changes in spike glycoprotein strain Strains the S1 subunit two subgroups variations [DOI] 10.1016/S0168-1702(02)00004-7 PMC 바로가기 [Article Type] Article