Atypical lymphocytes in the peripheral blood of COVID-19 patients: A prognostic factor for the clinical course of COVID-19Research Article Published on 2021-11-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Admission association Atypical Atypical lymphocyte Blood changes in clinical Clinical course Clinical finding Clinical improvement Comorbidities coronavirus disease Course COVID-19 COVID-19 patient demographics diagnosis and monitoring disease course disease onset eight Inpatient investigated knowledge lung infiltrate lymphocyte Lymphocytes material median time objective observation Patient patients Peripheral blood Pneumonia Prevalence Prognostic factor Radiographic Result shown significantly higher supplemental oxygen Symptoms Treatment [DOI] 10.1371/journal.pone.0259910 PMC 바로가기 [Article Type] Research Article
Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid and antibody tests up to 22 August 2020Research Published on 2021-11-112022-10-31 Journal: Eurosurveillance [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval Accuracy Antibody test antibody tests Area Asymptomatic clinical specificity confidence interval Continuous country COVID-19 COVID-19 pandemic defined diagnostic eight European heterogeneity hospitalised management Meta-analysis Mild nucleic acid nucleic acid test nucleic acid tests point-of-care point-of-care test point-of-care tests pooling Population Result SARS-CoV-2 SARS-CoV-2 nucleic acid sensitivity Sensitivity and specificity significantly higher specificity thresholds union [DOI] 10.2807/1560-7917.ES.2021.26.45.2001675 PMC 바로가기 [Article Type] Research
Mental health burden of patients with diabetes before and after the initial outbreak of COVID-19: predictors of mental health impairmentResearch Published on 2021-11-112022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] addition addressed affecting Anxiety anxiety symptom changes changes in Changes in mental health Course COVID-19 COVID-19 outbreak COVID-19 pandemic cross-sectional demographics Depression diabete diabetes diagnosed distress Efficacy eight examined Factor Germany Health Health status impairment IMPROVE Increased individual infected with SARS-CoV-2 information initial mental health outbreak over pandemic participant participated Patient patients with diabete patients with diabetes PHQ-2 predicted predictor Prevalence psychological support recall Result risk significant increase significantly supplementary material Symptoms [DOI] 10.1186/s12889-021-12101-z PMC 바로가기 [Article Type] Research
Re-emergence of enterovirus D68 in Europe after easing the COVID-19 lockdown, September 2021Rapid Communication Published on 2021-11-112022-10-31 Journal: Eurosurveillance [Category] Coronavirus, MERS, SARS, [키워드] acute flaccid myelitis COVID-19 diagnostic eight enterovirus Enterovirus D68 Europe European country expected infections lockdown MOST rapid increase reinforcement reported respiratory infection stimulated Surveillance typing widespread [DOI] 10.2807/1560-7917.ES.2021.26.45.2100998 PMC 바로가기 [Article Type] Rapid Communication
Immunosuppressants in Liver Transplant Recipients With Coronavirus Disease 2019: Capability or Catastrophe?—A Systematic Review and Meta-AnalysisMedicine Published on 2021-11-112022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] age Analysis Cardiopulmonary carried Chronic kidney disease CKD Comorbidities Comorbidity Complete coronavirus coronavirus disease COVID-19 database diabetes diagnosis of COVID-19 disease disorders eight heterogeneity hypertension Immunosuppressant Immunosuppression immunosuppressive immunosuppressive therapy inhibitor key consideration less liver liver transplant lowest mammalian Meta-analysis MMF Mortality mortality rate obesity organ pooled rate Prognosis Rapamycin recipient regimen rejection replaced review risk SARS-CoV-2 searched selected severe disease severity significantly Steroids survival the disease the patient therapy Transplant with COVID-19 Withdrawal [DOI] 10.3389/fmed.2021.756922 PMC 바로가기 [Article Type] Medicine
From chaos to control – experiences of healthcare workers during the early phase of the COVID-19 pandemic: a focus group studyResearch Published on 2021-11-102022-10-28 Journal: BMC health services research [Category] COVID-19, MERS, SARS, [키워드] Analysis approach Care caused Community concern conditions Confusion Coronavirus disease 2019 coronavirus SARS-CoV-2 COVID-19 COVID-19 pandemic COVID-19 patients Data analysis described disease early phase eight ENhance focus group discussion HCW HCWs Health personnel healthcare Healthcare system healthcare worker highlight hospital infecting Infection infection control Infection prevention information lifted mental health Nurses occupational health pandemic participated Patient Patient care performed personal health Personal protective equipment Physicians positive potentially life-threatening provide Qualitative qualitative research Result risk of infection Stress supplementary material Swedish transition Transmission unique variety virus transmission was used [DOI] 10.1186/s12913-021-07248-9 PMC 바로가기 [Article Type] Research
Deep Learning Algorithm for COVID-19 Classification Using Chest X-Ray Images흉부 X선 영상을 사용한 COVID-19 분류를 위한 딥 러닝 알고리즘Comparative Study Published on 2021-11-092022-09-11 Journal: Computational and Mathematical Methods in Medicine [Category] MERS, SARS, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition approach Chain Reaction Characteristics chest X-ray Chest X-ray image Chest X-ray images classification CNN CNNs Convolutional neural networks coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 diagnosis CXR dataset deep Diagnosis disease disease classification Diversity early diagnosis eight epidemic curve experimental analysis feature Features generative adversarial networks Government Image learning offer overcome pandemic Pneumonia provide Radiography recent Research respiratory resulting Reverse transcription-polymerase chain reaction RT-PCR SARS-CoV-2 Spread the epidemic toolkit training data triggered X-ray [DOI] 10.1155/2021/9269173 PMC 바로가기 [Article Type] Comparative Study
Humoral and cellular immunogenicity to a second dose of COVID-19 vaccine BNT162b2 in people receiving methotrexate or targeted immunosuppression: a longitudinal cohort studyArticles Published on 2021-11-092022-10-29 Journal: The Lancet Rheumatology [Category] COVID-19, [키워드] 95% CI Administered All participant Alpha Antibody Response B.1.1.7 B.1.617.2 BNT162b2 Cell cellular cellular immunity cellular response Cohort cohort study college Control COVID-19 vaccine defined Delta variants demonstrated detectable eight England evaluated extended interval finding foundation functional funding General population group healthy control healthy controls Humoral immunity IL-17 IL-2 IL-21 IL-23 immune response Immune-mediated inflammatory disease immunogenicity Immunosuppressant Immunosuppression individual inhibitor inhibitors interferon-γ IQR King London longitudinal cohort study magnitude male median median age methotrexate monotherapy Necrosis neutralising antibody Neutralising antibody responses neutralising antibody titre NHS NIHR no difference of BNT162b2 participant Patient Pfizer-BioNTech Primary outcome producing proportion psoriasis receiving recruited regimen robust SARS-CoV-2 variants second dose second vaccination single dose spike glycoprotein Spike-specific antibody spike-specific IgG spike-specific T-cell response study population T-cell Response the SARS-CoV-2 Thoma titre TNF Trust vaccination vaccine dose vaccine doses Volunteer white wild-type [DOI] 10.1016/S2665-9913(21)00333-7 PMC 바로가기 [Article Type] Articles
Laniakea@ReCaS: exploring the potential of customisable Galaxy on-demand instances as a cloud-based serviceSoftware Published on 2021-11-082022-10-27 Journal: BMC Bioinformatics [Category] COVID-19, [키워드] activities analyses bioinformatics Biomedical research cloud computing Community complex COVID-19 Critical effort eight ELIXIR facilitated flexible Galaxy global pandemic Improving initial instance introduced involved Laniakea NGS platform provide Research researcher resource Result SARS-CoV-2 Software environment Streamline supported [DOI] 10.1186/s12859-021-04401-3 PMC 바로가기 [Article Type] Software
Laniakea@ReCaS: exploring the potential of customisable Galaxy on-demand instances as a cloud-based serviceSoftware Published on 2021-11-082022-10-27 Journal: BMC Bioinformatics [Category] Coronavirus, COVID-19, Fulltext, MERS, SARS, [키워드] activities analyses bioinformatics Biomedical research cloud computing Community complex COVID-19 Critical effort eight ELIXIR facilitated flexible Galaxy global pandemic Improving initial instance introduced involved Laniakea NGS platform provide Research researcher resource Result SARS-CoV-2 Software environment Streamline supported [DOI] 10.1186/s12859-021-04401-3 PMC 바로가기 [Article Type] Software