Neutralizing activity
[대역어] 중립 활동
[용어속성] Action
[용어속성] Action
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses
Technical Advances and Resources
[키워드] antiviral activity
approach
chimeric
convalescent plasma
correlated
described
disease
epidemic of COVID-19
exhibited
HIV-1
Human immunodeficiency virus
human monoclonal antibodies
Human monoclonal antibody
Immunity
monoclonal antibody
neutralization potency
Neutralizing activity
Neutralizing antibodies
plasma
pseudotyped
reporter
robust
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 neutralization
SARS-CoV-2 neutralizing antibody
SARS-CoV-2–specific antibodies
sensitivity
stomatitis
vaccination
vesicular stomatitis virus
virus
VSV
while
[DOI] 10.1084/jem.20201181 PMC 바로가기 [Article Type] Technical Advances and Resources
[DOI] 10.1084/jem.20201181 PMC 바로가기 [Article Type] Technical Advances and Resources
Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals
Observation
[키워드] absence
acute COVID-19
acute respiratory syndrome
Analysis
approach
Clinical efficacy
clinical trial
collected
convalescent
convalescent individual
convalescent plasma
convalescent plasma trial
coronavirus
coronavirus disease
COVID-19
COVID-19 patient
cross-reactivity
D614G variant
Decline
Donor
effective vaccine
Efficacy
ELISA
evaluate
for inclusion
globe
glycoprotein
Humoral response
IgA
IgG
IgM
individual
Infection
interval
neutralization
neutralization activity
neutralize
Neutralizing activity
neutralizing antibody
Neutralizing titer
onset of symptom
patients
performed
plasma
plasma neutralization activity
positive
Prevent
PROTECT
pseudoparticle
RBD
repeated
required
resolution of symptoms
response
Safe
SARS-CoV-2
SARS-COV-2 infection
significant decrease
spike
spike glycoproteins
Symptoms
therapeutic options
therapy
thought
transfer
transfusion
treat
Treatment
Vaccine
while
wild-type SARS-CoV-2
[DOI] 10.1128/mBio.02590-20 PMC 바로가기 [Article Type] Observation
[DOI] 10.1128/mBio.02590-20 PMC 바로가기 [Article Type] Observation
Rapid in vitro assays for screening neutralizing antibodies and antivirals against SARS-CoV-2
Article
[키워드] acute respiratory syndrome
antibody
Antiviral
antiviral activity
antivirals
can be used
China
complex
Compound
coronavirus
coronavirus disease
Coronavirus-2
CoV
COVID-19
COVID-19 disease
death
described
drug
effective
food
global pandemic
Health
human infection
humans
identify
Impact
In vitro assay
inhibitors
mAb
mAbs
microneutralization
MNA
monoclonal antibodies
monoclonal antibody
neutralization
neutralize
Neutralizing
Neutralizing activity
Neutralizing antibodies
neutralizing antibody
Novel coronavirus
peroxidase
Plaque reduction microneutralization assay
polyclonal antibodies
Prophylactic
Rapid
reduce
reduction
reported
responsible
SARS-CoV
SARS-CoV-2
SARS-COV-2 infection
Scientific community
staining
Standardization
Therapeutic treatment
United State
Vaccine
while
Wuhan
[DOI] 10.1016/j.jviromet.2020.113995 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.jviromet.2020.113995 PMC 바로가기 [Article Type] Article
Virological Characterization of the First 2 COVID-19 Patients Diagnosed in Italy: Phylogenetic Analysis, Virus Shedding Profile From Different Body Sites, and Antibody Response Kinetics
Major Articles
[키워드] acute respiratory syndrome
Analysis
anatomical
antibody
Antibody Response
assist
Body
carried
characterization
clinical manifestation
clinical samples
collected
coronavirus
COVID-19
COVID-19 case
diagnosed
Diagnosis
early phase
evaluate
Hospitalization
IgA
IgG
IgM
Infection
Infectious virus
Italy
Kinetics
Laboratory
longitudinal analysis
Lower respiratory tract
Neutralizing activity
neutralizing antibody
ocular
Pathogenesis
Patient
Phylogenesis
positive
profile
Profiling
rectal
rescued
respiratory sample
Respiratory samples
response
Result
Saliva
SARS-CoV-2
SARS-CoV-2 RNA
serum
serum antibody
serum sample
shedding
specimen
Surveillance
swabs
tested
Transmission
Urine
viral culture
Viral RNA
viral RNA load
Virus shedding
vomit
was obtained
[DOI] 10.1093/ofid/ofaa403 PMC 바로가기 [Article Type] Major Articles
[DOI] 10.1093/ofid/ofaa403 PMC 바로가기 [Article Type] Major Articles
Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults
Clinical Trial
[키워드] acute respiratory syndrome
Administered
Adults
adverse event
age
assigned
binding
CD4
chills
conducted
Control
convalescent serum
coronavirus
coronavirus disease
cytokine response
death
dose
dose-dependent
dose-escalation
elicited
ENCODE
fatigue
geometric mean titer
GMT
headache
healthy
immunization
immunogenicity
incidence
include
Infection
Infectious disease
injection
Messenger RNA
Mild
moderate
mRNA-1273
mRNA-1273 vaccine
multiple methods
myalgia
Neutralizing activity
Neutralizing-antibody
neutralizing-antibody titer
Older
Older age
older population
Open-label
Pain
participant
Phase 3
prefusion
Prevent
receive
recipient
reported
response
Result
S-2P
Safety
SARS-CoV-2
SARS-CoV-2 spike protein
serum
severity
stratified
subgroup
Support
T cells
Testing
the median
Trial
type 1 helper
Vaccine
vaccine candidate
vaccine trial
[DOI] 10.1056/NEJMoa2028436 PMC 바로가기 [Article Type] Clinical Trial
[DOI] 10.1056/NEJMoa2028436 PMC 바로가기 [Article Type] Clinical Trial
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
Article
[키워드] Anti-spike
antibody
Antibody test
Area
assays
Blood
blood donor
COVID-19 patients
Diagnostic markers
Donor
Epidemiology
Evidence
hospitalized patient
IgG
IgM
Immunoglobulin
in vitro
indication
less
median time
Neutralising activity
Neutralizing activity
Neutralizing antibody titer
neutralizing capacity
Neutralizing titer
Patient
Population
populations
positive
Predictive
Protein
ranged
remained
San Francisco Bay
SARS-CoV-2
SARS-CoV-2 seroprevalence
SARS-CoV-2-specific antibody
Seroconversion
Serological testing
Surveillance
symptom onset
viral infection
[DOI] 10.1038/s41467-020-18468-8 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41467-020-18468-8 PMC 바로가기 [Article Type] Article
A comprehensive, longitudinal analysis of humoral responses specific to four recombinant antigens of SARS-CoV-2 in severe and non-severe COVID-19 patients
중증 및 비중증 COVID-19 환자에서 SARS-CoV-2의 4가지 재조합 항원에 대한 체액 반응에 대한 포괄적이고 종단적인 분석
Research Article
[키워드] accompanied
adaptive
affected
analyzed
antibody
Antibody Response
Antibody responses
Antigen
antigens
approved
cause
Combined
Community
convalescent phase
convalescent sera
coronavirus disease
Coronavirus disease 2019
correlated
COVID-19
COVID-19 patient
COVID-19 patients
disease onset
Disease progression
ECD
ectodomain
effective
effective drug
effective drugs
Evidence
Follow-up
global pandemic
hospital discharge
Humoral response
humoral responses
IgA
IgA response
IgG responses
IgM and IgG
indicated
information
Intervention
longitudinal analysis
magnitude
Most patient
Most patients
neutralization activities
neutralization activity
neutralization potency
neutralizing activities
Neutralizing activity
non-severe patients
nucleoprotein
pandemic
Patient
Prevent
profiles
progression
provide
RBD
Receptor binding domain
reduction
remained
reported
response
S1 protein
SARS-CoV-2
sensitivity
Serological assay
Serological testing
serum
Seven
severe COVID-19 patient
severe patients
shown
significantly
specificity
Spike protein
the disease
the SARS-CoV-2
the spike protein
treat
Treatment
understanding
Vaccine
Vaccine design
virus
[DOI] 10.1371/journal.ppat.1008796 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1008796 PMC 바로가기 [Article Type] Research Article
Cross-neutralization activity against SARS-CoV-2 is present in currently available intravenous immunoglobulins
Short Communication
[키워드] acute respiratory syndrome
antibody
Cell culture
coronavirus
CoV
COVID-19
COVID-19 pandemic
cross-neutralization
human coronavirus
in vitro
Infectivity
Intravenous immunoglobulin
material
MERS-CoV
Middle East
neutralization
neutralization activity
Neutralizing activity
plaque-forming unit
potential therapy
produced
quantified
reduction in
reported
SARS-CoV
SARS-CoV-2
SARS-CoV-2 isolates
syndrome
tested
virus
[DOI] 10.2217/imt-2020-0220 PMC 바로가기 [Article Type] Short Communication
[DOI] 10.2217/imt-2020-0220 PMC 바로가기 [Article Type] Short Communication
A comparison of four serological assays for detecting anti–SARS-CoV-2 antibodies in human serum samples from different populations
Research Article
[키워드] addition
antibody
antibody assay
antibody profiling
Antibody Response
Antibody titer
Antigen
Asymptomatic
Cell
COVID-19
difference
domain
ectodomain
ELISA assay
evaluate
expressed
flow cytometry
full-length
healthy blood donors
healthy individual
Hospitalized
hospitalized patient
human serum
immunoprecipitation
individual
infected with SARS-CoV-2
LIPS
Luciferase immunoprecipitation system
Mild
mild symptoms
neutralization activity
Neutralizing activity
occurred
pandemic
performed
pilot study
Population
Prevalence
Previous studies
profiles
Protein
pseudotype virus
S1 domain
SARS-CoV-2
SARS-CoV-2 antigen
SARS-COV-2 infection
SARS-CoV-2 seroprevalence
sensitivity
Seroconversion
Serological assay
serological assays
Seropositivity
serum sample
Severe case
severity
subpopulation
symptom onset
symptomatic
symptomatic case
symptomatic individual
the disease
the S protein
the SARS-CoV-2
trimeric spike
Virus neutralization
with COVID-19
[DOI] 10.1126/scitranslmed.abc3103 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1126/scitranslmed.abc3103 PMC 바로가기 [Article Type] Research Article