Outcomes of Patients With ST-Segment Elevation Myocardial Infarction Admitted During COVID-19 Pandemic Lockdown in Germany – Results of a Single Center Prospective Cohort StudyCardiovascular Medicine Published on 2021-04-202022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] accompanied Care center conducted Contact COVID-19 COVID-19 crisis COVID-19 pandemic declining deteriorate disease Elevation enrolled Epidemiology evaluated Follow-up Germany Health Healthcare professional In-hospital lockdown median morbidity and mortality Myocardial infarction numbers of patient outbreak outcome Patient patients Prospective Prospective Study Public reported Result serum troponin significantly spread of COVID-19 STEMI Support survival ventricular [DOI] 10.3389/fcvm.2021.638954 PMC 바로가기 [Article Type] Cardiovascular Medicine
Pregnancy Outcomes and Child Development Effects of SARS-CoV-2 Infection (PROUDEST Trial): Protocol for a Multicenter, Prospective Cohort StudyProtocol Published on 2021-04-202022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] Affect age Analysis baby Care Child development children clinical clinical decision clinically Cohort collected control subject COVID-19 development Effect enrolled Evidence excluded fetus growth Health Identifier immunological implication include infancy Infection Inflammatory Laboratory Laboratory tests Long-term follow-up metabolism mother multicenter Neonate Newborn objective offspring outcome pregnancies Pregnancy pregnant women Prospective prospective cohort study public health Registration report Result SARS-CoV-2 SARS-COV-2 infection Support Trial virus were infected women [DOI] 10.2196/26477 PMC 바로가기 [Article Type] Protocol
SARS-CoV-2 Antibody Screening in Healthcare Workers in Non-Infectious Hospitals in Two Different Regions of Southern Poland (Upper Silesia and Opole Voivodeships): A Prospective Cohort Study폴란드 남부의 서로 다른 두 지역(Upper Silesia 및 Opole Voivodeships)의 비감염성 병원 의료 종사자를 대상으로 한 SARS-CoV-2 항체 검사: 전향적 코호트 연구Article Published on 2021-04-202022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 치료기술, [키워드] antibody screening Asymptomatic benefit blood collection coronavirus coronavirus SARS-CoV-2 COVID-19 detection determine different time point ELISA test emergency wards evaluated had no HCW HCWs health-care professionals healthcare healthcare worker Healthcare workers hospital Hospital environment Host human coronavirus IgA IgG IgM IgM/IgG immunoglobulins individual Infection Local negative RT-PCR New coronavirus non-infectious patients PCR test PCR testing performed Poland Population positive Prevalence Prospective reduce Region risk RT-PCR RT-PCR test RT-PCR testing sampling SARS-CoV-2 SARS-COV-2 infection Screening semi-quantitative ELISA sera serologic responses serological surveillance Seropositivity socio-demographic Spread Symptoms symptoms of infection test results university university hospital upper Volunteer worker [DOI] 10.3390/ijerph18084376 PMC 바로가기 [Article Type] Article
Molecular structure, NBO analysis of the hydrogen-bonded interactions, spectroscopic (FT-IR, FT-Raman), drug likeness and molecular docking of the novel anti COVID-2 molecule (2E)-N-methyl-2-[(4-oxo-4H-chromen-3-yl)methylidene]-hydrazinecarbothioamide (Dimer) – quantum chemical approach분자 구조, 수소 결합 상호 작용의 NBO 분석, 분광(FT-IR, FT-Raman), 새로운 항 COVID-2 분자(2E)-N-메틸-2-[(4- 옥소-4H-크로멘-3-일)메틸리덴]-히드라진카르보티오아미드(이량체) - 양자 화학적 접근Article Published on 2021-04-152022-08-31 Journal: Spectrochimica acta. Part A, Molecular and biomole [Category] SARS, 치료제, [키워드] (2E)-N-methyl-2-[(4-oxo-4H-chromen-3-yl)methylidene]-hydrazinecarbothioamide Absorption Analysis analyzed Antiviral approach binding energy carried chromone cysteine density Density functional theory difference dimer distribution distributions docking drug excretion FIVE Fourier transform Frequency FT-IR and Raman spectra functional histidine hydrogen Hyperconjugation Hyperconjugation-Rehybridization idea inhibiting Interaction interactions intermolecular contact intermolecular contacts intermolecular hydrogen bond intermolecular interaction investigated metabolism molecular docking pharmacokinetic potential energy Prospective SARS-CoV-2 protease SARS-CoV-2 protein SARS-COVID-19. side chain Simulation Substitution Toxicity [DOI] 10.1016/j.saa.2020.119388 PMC 바로가기 [Article Type] Article
The Avon Longitudinal Study of Parents and Children – A resource for COVID-19 research: Generation 2 questionnaire data capture May-July 2020Data Note Published on 2021-04-142022-10-28 Journal: Wellcome Open Research [Category] COVID-19, [키워드] affected ALSPAC Bristol children Children of the 90s children’s health Cohort Contact Contact patterns coronavirus COVID-19 COVID-19 pandemic Cross-generation dataset enrolled Generation Health initial lockdown lockdown restriction longitudinal management mental health National offspring pandemic parent parental parents participant population-based cohort pregnant pregnant women Prospective questionnaire questionnaire data recruited released Research resource response Sociodemographic supported unique women [DOI] 10.12688/wellcomeopenres.16414.2 PMC 바로가기 [Article Type] Data Note
A COVID-19 Rehabilitation Prospective Surveillance Model for Use by PhysiotherapistsArticle Published on 2021-04-142022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Affect arising cardiorespiratory cardiorespiratory system Complication components coronavirus disease COVID-19 defined facilitate Health Impact include Level management Medicine mental health Model neuromuscular system Oxford Patient Physiotherapist prevented professional Prospective prospective surveillance model provide rehabilitation required Surveillance the disease treated [DOI] 10.3390/jcm10081691 PMC 바로가기 [Article Type] Article
Personal protective equipment for reducing the risk of COVID-19 infection among health care workers involved in emergency trauma surgery during the pandemic: An umbrella reviewReview Article Published on 2021-04-122022-10-30 Journal: The journal of trauma and acute care surgery [Category] COVID-19, MERS, SARS, [키워드] adhere approach Assessing assessment automated broad evidence synthesis Canada Care conducted Contagion Controlled country COVID-19 criteria decontamination development Effect effective Efficacy ENhance equipment Evidence evidence-based practice eye feasible global health Health health care facility Health care worker health care workers hydrogen peroxide Infection involved Mask Masks measure moderate N95 masks N95 respirator not affect observational study overcome patients Personal protective equipment platform PPE Prospective Protective Quality recommendations reduce reduced risk reducing reduction in Registered reported resources Respirator reuse review risk risk of COVID-19 surgical trauma Trauma surgery ultraviolet Umbrella review [DOI] 10.1097/TA.0000000000003073 PMC 바로가기 [Article Type] Review Article
Shaping Workflows in Digital and Remote Diabetes Care During the COVID-19 Pandemic via Service Design: Prospective, Longitudinal, Open-label Feasibility TrialOriginal Paper Published on 2021-04-052022-10-31 Journal: JMIR mHealth and uHealth [Category] Coronavirus, MERS, SARS, [키워드] accounted approach Care children clinical clinical care Clinical outcome COVID-19 COVID-19 pandemic diabete diabetes Digital digital care Digital health ENhance enrolled evaluate Factor feasibility Germany Glucose Health hyperglycemia hypoglycemia IMPROVE improvement insulin lockdown longitudinal monitors objective Open source outcome pandemic Participants pediatric diabetes performed platform Prospective Quality of life Registration remote Remote care Result service service design shaping significantly Support telehealth Telemedicine Type 1 diabetes university hospital were assessed were used Workflow [DOI] 10.2196/24374 PMC 바로가기 [Article Type] Original Paper
Umbilical cord clamping and skin-to-skin contact in deliveries from women positive for SARS-CoV-2: a prospective observational studySARS-CoV-2 양성인 여성의 분만 시 탯줄 조이기 및 피부 대 피부 접촉: 전향적 관찰 연구Observational Study Published on 2021-04-012022-09-11 Journal: BJOG : an international journal of obstetrics and [Category] SARS, 임상, 치료기술, [키워드] 24 hour 24 hours Breastfeeding collected confirmed case Contact COVID-19 DCC epidemiological group Infant Infection information mother nasopharyngeal Neonatal Neonate Neonates Newborn no difference no differences no significant differences observational study outcome PCR test performed positive postpartum period pregnant women Prospective prospective observational study registry Safe Safety SARS-CoV-2 SARS-COV-2 infection significant difference significantly higher skin skin-to-skin Spanish Transmission transmission of SARS-CoV-2 umbilical Umbilical cord umbilical cord clamping vertical transmission was collected women [DOI] 10.1111/1471-0528.16597 PMC 바로가기 [Article Type] Observational Study
Plasma Exchange to Rescue Patients with Autoantibodies Against Type I Interferons and Life-Threatening COVID-19 PneumoniaI형 인터페론 및 생명을 위협하는 COVID-19 폐렴에 대한 자가항체가 있는 환자를 구조하기 위한 혈장 교환Article Published on 2021-04-012022-09-11 Journal: Journal of Clinical Immunology [Category] MERS, SARS, 진단, 치료기술, [키워드] Against anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody autoantibodies autoantibody Blood blood concentrations Case series clinical benefit Concentration concentrations control patient controls COVID-19 COVID-19 patient COVID-19 pneumonia Critically ill detectable diagnosed died discharged exchange FIVE French Hospital stay ICU ICU admission ICUs IFN IFNs intensive care unit interferons life-threatening Lower respiratory tract men Neutralizing one patient Patient patients plasma plasma exchange plasma exchanges Pneumonia positive Prospective remained rescue respiratory RT-PCR SARS-CoV-2 SARS-COV-2 infection serum serum IFN-α level serum IFN-α levels survivor tested the patient therapy tracheal aspirate Tracheal aspirates treated Two patient two patients Type Type I IFN type I IFNs type I interferon type I interferons upper and lower respiratory tract upper respiratory tract Viral Viral load was determined were measured were used without affecting [DOI] 10.1007/s10875-021-00994-9 PMC 바로가기 [Article Type] Article