The Effects of ATIR Blocker on the Severity of COVID-19 in Hypertensive Inpatients and Virulence of SARS-CoV-2 in Hypertensive hACE2 Transgenic MiceOriginal Article Published on 2022-01-012022-10-29 Journal: Journal of Cardiovascular Translational Research [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] ACE2 ACE2 expression acute respiratory syndrome angiotensin converting enzyme 2 antihypertensive drugs AT1 AT1 receptor blocker AT1R ATIR Biomarker blocker cellular entry coronavirus Coronavirus disease 2019 COVID-19 COVID-19 patient CRP determine Effect enzyme hACE2 had no Heart injury higher risk hospitalized COVID-19 patient hypertension hypertensive hypertensive COVID-19 patient hypertensive patient IL-1 IL-6 inflammation marker Inpatient kidney outcome Post-infection receptor renin-angiotensin system required SARS-CoV-2 SARS-COV-2 infection serum severity supplementary material transgenic mice treated Treatment [DOI] 10.1007/s12265-021-10147-3 PMC 바로가기 [Article Type] Original Article
Association of Vitamin D Status and COVID-19-Related Hospitalization and MortalityOriginal Research Published on 2022-01-012022-10-31 Journal: Journal of General Internal Medicine [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Affair Blood Care Clinical outcome Cohort cohort study Concentration concentrations conducted Contact Continuous continuous variable Controlled trial coronavirus covariate covariates COVID-19 death deficiency Department died evaluate exposure Health homogeneous Hospitalization independent Isolation log-transformed measure Mortality objective outcomes Patient patients Population positive Probability receiving Result risk SARS-CoV-2 SARS-CoV-2 test social determinant status study outcome supplementary material veteran Vitamin D Vitamin D status Vitamin D supplementation [DOI] 10.1007/s11606-021-07170-0 PMC 바로가기 [Article Type] Original Research
The Unequal Effects of Social Distancing Policy on Subway Ridership during the COVID-19 Pandemic in Seoul, South KoreaBrief Report Published on 2022-01-012022-10-30 Journal: Journal of Urban Health : Bulletin of the New York [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] changes collected costly COVID-19 decrease Effect essential worker exhibited index log-transformed nine Policy proportion social distancing South Korea subway supplementary material the mean [DOI] 10.1007/s11524-021-00585-4 PMC 바로가기 [Article Type] Brief Report
Mesenchymal stem/stromal cell-based therapies for severe viral pneumonia: therapeutic potential and challengesReviews Published on 2021-12-312022-10-30 Journal: Intensive Care Medicine Experimental [Category] COVID-19, [키워드] acute hypoxic respiratory failure acute respiratory distress syndrome added aetiology Anti-viral therapy attenuate Cell Cell therapy Cell-based therapy cellular Clinical studies clinical study coronavirus COVID-19 pandemic Critical illness demonstrated early phase Endemic ENhance Epidemiology globe in vivo Influenza investigated Lung injury management Mesenchymal stem cells morbidity and mortality MSC MSCs outbreak pandemic Pandemics Pneumonia receiving safety profile Sepsis severe viral pneumonia supplementary material therapeutic approaches therapeutic potential therapeutic strategy therapy these cell These cells tissue translation Trial urgency viral epidemics Viral pneumonia viruses while [DOI] 10.1186/s40635-021-00424-5 PMC 바로가기 [Article Type] Reviews
Myocardial injury in hospitalized COVID-19 patients: a retrospective study, systematic review, and meta-analysisResearch Published on 2021-12-312022-10-27 Journal: BMC Public Health [Category] COVID-19, [키워드] Acute kidney injury age cardiovascular disease Chronic kidney disease Clinical outcome COVID-19 patient death discharge Healthcare system hospital Hospitalized hospitalized COVID-19 hypertension increased mortality Injury likelihood majority Meta-analysis myocardial injury Older outcomes Patient patient population patients hospitalized performed Prevalence ranged Result Retrospective analysis Retrospective study Shock significantly similar study supplementary material survival systematic review the United State with COVID-19 [DOI] 10.1186/s12872-021-02450-3 PMC 바로가기 [Article Type] Research
Myocardial injury in hospitalized COVID-19 patients: a retrospective study, systematic review, and meta-analysisResearch Published on 2021-12-312022-10-27 Journal: BMC Public Health [Category] Coronavirus, COVID-19, SARS, [키워드] Acute kidney injury age cardiovascular disease Chronic kidney disease Clinical outcome COVID-19 patient death discharge Healthcare system hospital Hospitalized hospitalized COVID-19 hypertension increased mortality Injury likelihood majority Meta-analysis myocardial injury Older outcomes Patient patient population patients hospitalized performed Prevalence ranged Result Retrospective analysis Retrospective study Shock significantly similar study supplementary material survival systematic review the United State with COVID-19 [DOI] 10.1186/s12872-021-02450-3 PMC 바로가기 [Article Type] Research
The effects of the COVID-19 pandemic on psychological stress in breast cancer patientsResearch Published on 2021-12-312022-10-28 Journal: BMC Cancer [Category] COVID-19, [키워드] “COVID-19 affected age Breast cancer breast cancer patient breast cancer patients caused Comprehensive coping COVID-19 COVID-19 infection COVID-19 pandemic defined demographic factor demonstrated Diagnosis distress Effect European help highest identify Intensive inventory majority not differ organization pandemic parameter participant Patient Psychological Psychological distress psychological health psychological support psychologically questionnaire receiving recruited reported Result SARS-CoV-2 screened significant effect significantly Stress subgroup subpopulation subsequent supplementary material susceptible Symptoms therapeutic therapy Thermometer [DOI] 10.1186/s12885-021-09012-y PMC 바로가기 [Article Type] Research
Metagenomic Analysis Reveals Previously Undescribed Bat Coronavirus Strains in EswatiniShort Communication Published on 2021-12-302022-10-31 Journal: EcoHealth [Category] COVID-19, [키워드] alphacoronavirus bat bats Betacoronavirus Chiroptera coronavirus Emerging infectious diseases Evidence fecal samples Genome human–wildlife interface investigated Mop potential risk Prevalence Scotophilus Sequencing strain supplementary material Surveillance zoonotic disease [DOI] 10.1007/s10393-021-01567-3 PMC 바로가기 [Article Type] Short Communication
Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infectionSARS-CoV-2 감염에 대한 자가항체 반응의 역설적인 성별 특정 패턴Research Published on 2021-12-302022-09-10 Journal: Journal of Translational Medicine [Category] SARS, 진단, 치료법, [키워드] AABs absence Activation acute response age analyses antibody Antigen antigens assigned asymptomatic infection autoantibody autoantigen Autoantigen selectivity Autoimmune Autoimmune disease Autoimmune diseases autoreactivity blood draw breadth classic clinical disease Clustering Cohort collected COVID-19 COVID-19 illness demographic data effective intervention effective interventions Evidence evidence of exhibit extreme greater healthy control homology Immune-mediated inflammatory activity lead men men and women modulating molecular multivariable analyses nucleocapsid protein number of symptom participant presence or absence Prevalence reactivity reported symptom reported symptoms Result SARS-CoV-2 SARS-COV-2 infection serological severe COVID-19 illness Sex difference sex differences socio-demographic supplementary material susceptibility Symptom symptomatic infection Symptoms trajectory triggered within 6 months women [DOI] 10.1186/s12967-021-03184-8 PMC 바로가기 [Article Type] Research
Embeddings from protein language models predict conservation and variant effectsArticle Published on 2021-12-302022-11-15 Journal: Human Genetics [Category] COVID19(2023년), SARS, 변종, [키워드] Algorithm alignment Amino acid analyses applied approach data set database deep deep learning Effect embedding entire sequence expand experiment fraction human proteins investigated language Local Logistic regression magnitude Model Multiple sequence alignment Nvidia Pearson correlation predict predicted prediction Probability Protein protein sequences Proteins proteome regions residue RTX SARS-CoV-2 variant scanning score sequence Sequence conservation significantly Spearman statistically supplementary material variant while [DOI] 10.1007/s00439-021-02411-y PMC 바로가기