Are type 1 interferons treatment in Multiple Sclerosis as a potential therapy against COVID-19?Case report Published on 2020-07-012022-10-05 Journal: Multiple sclerosis and related disorders [Category] SARS, 치료법, [키워드] China Clinical prognosis complications coronavirus 2 COVID-19 COVID-19 affected patients D-dimer death discharged disease effective Elderly patient elevated high risk higher risk Hospitalization lymphopenia Mild Multiple multiple sclerosis no symptoms pandemic Patient patients with comorbidity potential therapy Potential treatment respiratory Result sclerosis Support Symptom tested the patient therapy thought treated Treatment type 1 interferon [DOI] 10.1016/j.msard.2020.102196 [Article Type] Case report
Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy — Achieving global consensus and visibility for cellular host-directed therapiesEditorial Published on 2020-07-012022-10-05 Journal: International Journal of Infectious Diseases [Category] SARS, 신약개발, 임상, [키워드] agency antiviral drug blueprint cause caused Cell cellular circulating clinical clinical trial Combination combinations Community Consensus COVID-19 COVID-19 mortality death death rate disease effective HDTs Host host-directed therapy immune Inflammatory response initiated long-term functional disability MERS-CoV morbidity Mortality mortality rates MSC MSC therapy MSCs novel coronavirus disease ongoing trial pandemic pathogen pathogenesis of SARS-CoV-2 Patient reducing mortality regimen registry reported Repurposed drug severe COVID-19 disease specific treatment STEM the WHO therapeutic interventions therapy Treatment treatment trial Trial turn underlie Vaccine WHO WHO ICTRP World Health Organization [DOI] 10.1016/j.ijid.2020.05.040 [Article Type] Editorial
Respiratory conditions in coronavirus disease 2019 (COVID-19): Important considerations regarding novel treatment strategies to reduce mortalityResearch article Published on 2020-07-012022-10-05 Journal: Medical Hypotheses [Category] SARS, 치료법, [키워드] 2019 novel coronavirus 2019-nCoV 2019-nCoV/SARS-CoV-2 acute respiratory distress ARDS binding Blood cause Cell Chloroquine clinically condition conditions coronavirus disease COVID-19 COVID-19 cases COVID-19 patient Critical described develop developmental effective EPO feature hallmark hemoglobin high mortality Hydroxychloroquine imperative life-threatening management medication Organ failure oxygen Oxygen therapy Oxygenation pulmonary reduce mortality respiratory respiratory symptoms SARS-CoV-2 Sickness significantly Stage Support Symptom syndrome therapeutic therapeutic intervention therapy tissue Treatment treatment strategy treatments for COVID-19 Trial Vaccine ventilator virus with COVID-19 [DOI] 10.1016/j.mehy.2020.109760 [Article Type] Research article
COVID-19 in a MS patient treated with ocrelizumab: does immunosuppression have a protective role?Case report Published on 2020-07-012022-10-05 Journal: Multiple sclerosis and related disorders [Category] SARS, 유전자 메커니즘, [키워드] B cell B-cell Clinical deterioration Complete Complication coronavirus disease 19 COVID-19 COVID-19 affected patients death depleting discharged disease disease entity Elderly patient Follow-up high risk higher risk Hospitalization Hypothesis immune response Immunosuppressant Immunosuppression immunosuppressive infected patient monoclonal antibody multiple sclerosis occurred overactive Patient patient symptom patients with comorbidity Potential treatment Protective Result Support Symptom tested therapy treated [DOI] 10.1016/j.msard.2020.102120 [Article Type] Case report
Convalescent plasma: A possible treatment protocol for COVID- 19 patients suffering from diabetes or underlying liver diseasesResearch article Published on 2020-07-012022-10-05 Journal: Diabetes & metabolic syndrome [Category] SARS, 치료법, [키워드] ACE2 adverse effects affected collected convalescent plasma country COVID COVID-19 COVID-19 patient critical COVID-19 patient diabete diabetes Elsevier Francis globe Google infected individual Infection liver Liver disease liver diseases liver dysfunction Nature Neutralizing antibodies Occurrence pandemic Patient plasma protocol randomised clinical trial recovered patient Result risk SARS-CoV-2 SARS-COV-2 infection specific treatment symptomatic Taylor therapy treat Treatment Treatment protocol underlying disease viral disease viral infection WHO guidelines [DOI] 10.1016/j.dsx.2020.05.023 [Article Type] Research article
Calcineurin Inhibitor-Based Immunosuppression and COVID-19: Results from a Multidisciplinary Cohort of Patients in Northern ItalyCommunication Published on 2020-06-302022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory distress Administered calcineurin calcineurin inhibitors Clinical course CNI cohort of patient cohort study collected Comorbidities consecutive patient Course COVID-19 COVID-19 outbreak COVID-19 patient COVID-19 patients diarrhea died disease disorder evaluate evaluated Fever generally mild hospital Hospitalized Immunosuppression Infectious complications inhibitor inhibitors IQR Italy males median age North outcome Patient presenting Result Rheumatic diseases risk solid organ transplantation syndrome therapy Treatment [DOI] 10.3390/microorganisms8070977 PMC 바로가기 [Article Type] Communication
Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19Immunology Published on 2020-06-302022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome clinical feature co-morbidities coronavirus COVID-19 COVID-19 disease develop disease pathogenesis effort Genetic healthy individual help Host immune defenses Host immune response identify immune pathway immunopathology increased risk Infection Innate immunity knowledge later phase medication pandemic Pandemics pathway Patient preventative measures Primary Immunodeficiency Prophylactic Prophylaxis recent finding role SARS-coronavirus 2 SARS-CoV-2 SARS-COV-2 infection susceptibility Symptom target therapy understanding vaccination whole exome sequencing [DOI] 10.3389/fimmu.2020.01606 PMC 바로가기 [Article Type] Immunology
Combined long-pulsed Nd-Yag laser and itraconazole versus itraconazole alone in the treatment of onychomycosis nailsArticle Published on 2020-06-302024-08-30 Journal: Journal of Dermatological Treatment [Category] 백선증, [키워드] 1064-nm long-pulsed Nd-Yag laser itraconazole Onychomycosis therapy PMC 바로가기
Body Composition Findings by Computed Tomography in SARS-CoV-2 Patients: Increased Risk of Muscle Wasting in ObesityArticle Published on 2020-06-302022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS, [키워드] applied assist Body body composition caused characteristic complex Complication Computed tomography COVID-19 COVID-19 patient CT scan Diagnostic imaging diagnostics evaluate fat finding frailty greater help high risk Hospitalization ICU increase in Increased increased risk Inflammation lean lean mass liver liver attenuation Long low-grade inflammation Malnutrition management muscle Muscle wasting nutritional status obese obesity paradoxical parameter Pathways Patient profile recognize reduce risk SARS-CoV-2 subjects therapy treat wasting [DOI] 10.3390/ijms21134670 PMC 바로가기 [Article Type] Article
Population differentiation, antifungal susceptibility, and host range of Trichophyton mentagrophytes isolates causing recalcitrant infections in humans and animals인간과 동물에서 난치성 감염을 일으키는 Trichophyton mentagrophytes 분리주의 집단 차이, 항진균 감수성 및 숙주 범위Original Article Published on 2020-06-302024-07-28 Journal: European Journal of Clinical Microbiology & Infect [Category] 백선증, [키워드] antifungal resistance dermatophytes genomic diversity Keratinolytic activity pathogenicity public health therapy Trichophyton mentagrophytes [DOI] 10.1007/s10096-020-03952-2 PMC 바로가기 [Article Type] Original Article