interleukin-6 – Page 44 – Communicable Diseases Research

Factors associated with acute cardiac injury and their effects on mortality in patients with COVID-19

급성 심장 손상과 관련된 요인 및 COVID-19 환자의 사망률에 미치는 영향

Article

Published on 2020-11-242022-09-10
Journal: Scientific Reports [Category] SARS, 바이오마커,

Correlation of interleukin-6 with Epstein–Barr virus levels in COVID-19

COVID-19에서 인터루킨-6과 엡스타인-바 바이러스 수준의 상관관계

Research Letter

Published on 2020-11-232022-09-11
Journal: Critical Care [Category] SARS, 바이오마커,

[키워드] Coronavirus disease 2019 COVID-19 EBV Epstein–Barr virus Epstein–Barr virus IL-6 Inflammation interleukin-6 SARS-CoV-2 severe acute respiratory syndrome coronavirus 2
[DOI] 10.1186/s13054-020-03384-6 PMC 바로가기 [Article Type] Research Letter

Risk for COVID-19 infection in patients with tobacco smoke-associated cancers of the upper and lower airway

Review Article

Published on 2020-11-202022-10-31
Journal: European archives of oto-rhino-laryngology : offic [Category] COVID-19, MERS, SARS,

[키워드] ACE2 Activation advanced age airway Cancer cerebrovascular diseases characterized chronic inflammation chronic obstructive clinical Clinical course Clinical outcome Comorbidity condition COPD COVID-19 COVID-19 infection COVID-19 patient cytokine cytokine release epithelial Factor Gender Head neck cancer iatrogenic IL-6 immune Immunity impairment increased risk Infection Inflammation inflammatory cell Interaction interleukin-6 key factor lower airway lung cancer male morbidity and mortality Multi-organ damage nasal occur overexpressed pathophysiological Patient Patients with cancer receptors respiratory cell Respiratory disease respiratory infectious disease Result review risk Risk factors SARS-CoV-2 replication smoker Smokers syndrome the cytokine storm TMPRSS2 tobacco smoke triggering viral infection
[DOI] 10.1007/s00405-020-06456-z PMC 바로가기 [Article Type] Review Article

Computed tomography characterization and outcome evaluation of COVID-19 pneumonia complicated by venous thromboembolism

Research Article

Published on 2020-11-192022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS, SARS,

[키워드] adverse outcome affected age analyzed assigned Blood BNP C-reactive protein calculated Care Characteristics Chest CT Cohort Comorbidities conducted consecutive patient correlated COVID-19 CT finding D-dimer death described detect Diagnosis discharge disease ECMO elevated evaluated Evidence extracorporeal membrane oxygenation fibrinogen Follow-up Gender higher risk ICU incidence include intensive care interleukin-6 Laboratory lactate dehydrogenase LDH logistic regression model low-dose majority material mechanical ventilation N-terminal NT-proBNP outcome Patient patients performed Pneumonia positive pro-B-type natriuretic peptide pulmonary angiography Result Retrospective study RT-PCR significantly statistical analysis statistically significant symptom onset Symptoms tertiary care hospital threshold thrombosis tomography transfer Treatment troponine two group Two patient Univariate analysis Venous Thromboembolism VTE was performed
[DOI] 10.1371/journal.pone.0242475 PMC 바로가기 [Article Type] Research Article

A Review of Treatment of Coronavirus Disease 2019 (COVID-19): Therapeutic Repurposing and Unmet Clinical Needs

Pharmacology

Published on 2020-11-172022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] acute respiratory syndrome alleviate anti-viral agents antiviral agent Antiviral effect Asymptomatic benefit blunt children China Chinese Chloroquine clinical clinical evidence clinical trial convalescent plasma coronavirus disease Coronavirus-2 COVID-19 COVID-19 patient Critical critical COVID-19 patient cytokine release Cytokine release syndrome drug early stage Efficacy Favipiravir highlight Hydroxychloroquine in vitro Inflammation inhibit inhibitor initial interferon interleukin-6 interleukin-6 inhibitors late stage Mild MOST Negative conversion non-randomized observational study pandemic Patient patients with COVID-19 Pediatric case Prophylaxis repurposing review ribavirin sample-size SARS-CoV-2 severe COVID-19 patient severe patients small sample size Study design therapeutic option therapy Traditional Chinese medicine Treatment treatment initiation with mild disease
[DOI] 10.3389/fphar.2020.584956 PMC 바로가기 [Article Type] Pharmacology

Prognostic factors for severity and mortality in patients infected with COVID-19: A systematic review

COVID-19에 감염된 환자의 중증도 및 사망률에 대한 예후 인자: 체계적인 검토

Research Article

Published on 2020-11-172022-08-13
Journal: PLoS ONE [Category] Biology and Life Sciences, COVID-19, MERS, SARS,

[키워드] abdominal pain age albumin anorexia applied Arterial hypertension arthralgia aspartate Aspartate aminotransferase AST Bilirubin Blood blood bilirubin blood cell blood platelet Blood urea nitrogen BNP C-reactive protein Cancer Cardiac arrhythmia cardiovascular disease Care CENTRAL Cerebrovascular disease certainty Chronic kidney disease chronic obstructive chronic obstructive pulmonary disease clinician Comorbidities conducted Controlled controlled trials creatine creatine kinase creatinine CRP D-dimer data extraction database Decision-making decrease Dementia demographic Demographic factors develop diabetes disease severity dyslipidemia Dyspnea eligibility erythrocyte sedimentation erythrocyte sedimentation rate Evidence examined facilitate Factor fatigue Fever GRADE haemoptysis help hypertension Hypoxemia Identified identify IL-6 IMPROVE infected with COVID-19 Infectious disease information interleukin-6 Kidney disease Laboratory Lactate lactate dehydrogenase LDH low blood pressure lymphocyte Lymphocyte count Male sex management meta-analyses Meta-analysis moderate Mortality multivariable prognostic model multivariable prognostic models myalgia myocardial injury neutrophil neutrophil count nitrogen obstructive pulmonary disease Organ failure outcome outcomes Patient patients with COVID-19 peptide performed Physical examination plasma Platelet count pleural effusion procalcitonin prognostic Prognostic factor Prognostic factors PROSPERO pulmonary disease radiological registration number researcher Respiratory failure Result Risk of bias SARS-CoV-2 screened sedimentation rate sequential organ failure assessment score severe disease severity smoking SOFA score Study design systematic review Tachycardia tachypnea urea variable WBC white
[DOI] 10.1371/journal.pone.0241955 PMC 바로가기 [Article Type] Research Article

Inflammatory Biomarker Trends Predict Respiratory Decline in COVID-19 Patients

염증성 바이오마커 트렌드, COVID-19 환자의 호흡 감소 예측

Article

Published on 2020-11-172022-09-11
Journal: Cell Reports Medicine [Category] Coronavirus, MERS, SARS, 바이오마커,

[키워드] acute respiratory distress acute respiratory distress syndrome Analysis C-reactive protein C-reactive protein (CRP coronavirus disease Coronavirus disease 2019 correlated COVID-19 CRP CRP level CRP levels cytokine Cytokine storm D-dimer Decline Deterioration disease examination ferritin Hospitalization Hospitalized hypoxemic Hypoxemic respiratory failure IL-6 Increasing Inflammation inflammatory biomarker level inflammatory biomarker levels initial intensive care intensive care unit interleukin-6 intubation measure Patient patients physiological plateau predict Proinflammatory cytokine respiratory respiratory distress Respiratory failure Respiratory function respiratory function) retrospective cohort reveal rising ROX sensitivity single-center subsequent subset trend
[DOI] 10.1016/j.xcrm.2020.100144 PMC 바로가기 [Article Type] Article

First Report of Tocilizumab Use in a Cohort of Latin American Patients Hospitalized for Severe COVID-19 Pneumonia

Medicine

Published on 2020-11-162022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] addition adverse event average COVID-19 COVID-19 patient COVID-19 patients Culture dose effective evaluated Evidence fractional inspired oxygen hyperinflammation hyperinflammatory state hypertension impairment Inflammation interleukin-6 intravenous intubation laboratory parameter Latin less lymphocyte Lymphocyte count mechanical ventilalion mechanical ventilation men Non-invasive obese oxygen PaO parameter Patient positive receiving report required Respiratory failure retrospective cohort study SARS-CoV 2 selected severe COVID-19 significantly standard treatment Tocilizumab Treatment utility ventilatory
[DOI] 10.3389/fmed.2020.596916 PMC 바로가기 [Article Type] Medicine

D-Dimer, Fibrinogen, and IL-6 in COVID-19 Patients with Suspected Venous Thromboembolism: A Narrative Review

정맥 혈전 색전증이 의심되는 COVID-19 환자의 D-이량체, 피브리노겐 및 IL-6: 내러티브 검토

Review

Published on 2020-11-132022-09-10
Journal: Vascular Health and Risk Management [Category] MERS, 바이오마커,

[키워드] activated acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus aPTT ARDS China Coagulation Coagulopathy coronavirus coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 patient COVID-19 patients critical COVID-19 patient critical COVID-19 patients Critically ill critically ill patients Cytokine storm D-dimer D-dimers Deep vein Deep vein thrombosis Degradation develop Disease progression Disseminated intravascular coagulation District DVT early diagnosis elevated Evidence evidence of Fever FIBRIN fibrin degradation products fibrinogen Fibrinogen levels global pandemic Health Organization heparin highlighting hyperactivity IL-6 include interleukin interleukin-6 intravascular coagulation Laboratory parameters lethargy LMWH low molecular weight low molecular weight heparin manifestation Mortality multiple organ failure narrative Organ failure Platelets Prognostic factor Prophylaxis prothrombin Prothrombin time Pulmonary embolism reducing respiratory respiratory distress review risk SARS-CoV-2 Seafood severe acute respiratory syndrome Coronavirus shown stages Suspected syndrome THROMBOPLASTIN Thromboprophylaxis thrombosis Thrombosis prophylaxis thrombotic thrombotic event Thrombotic events Treatment upper respiratory symptom upper respiratory symptoms Venous Thromboembolism VTE West WHO World Health Organization
[DOI] 10.2147/VHRM.S280962 PMC 바로가기 [Article Type] Review

Serum Interleukin-6 Concentrations and the Severity of COVID-19 Pneumonia: A Retrospective Study at a Single Center in Bengbu City, Anhui Province, China, in January and February 2020

Article

Published on 2020-11-112023-07-01
Journal: Medical science monitor : international medical jo [Category] SARS,

[키워드] COVID-19 interleukin-6 Pneumonia Severe acute respiratory syndrome
[DOI] 10.12659/MSM.926941 PMC 바로가기