Mathematical modeling of interaction between innate and adaptive immune responses in COVID‐19 and implications for viral pathogenesisResearch Article Published on 2020-05-132022-10-04 Journal: Journal of medical virology [Category] MERS, SARS, 치료제, [키워드] adaptive Adaptive immune response Adaptive immunity Analysis antiviral drugs applied cause caused complications coronavirus COVID‐19 COVID‐19 patient COVID‐19 patients COVID‐19 Disease progression early phase epithelial cell Host immune response Immunity implication Infection Influenza Influenza virus innate immune response Innate immunity Interaction lung mathematical Mortality opposite pandemic Pathogenesis patients potential treatment option SARS‐CoV‐2 virus SARS‐CoV‐2 severity Suppressing target cell‐limited model the timing viral clearance Viral load viral pathogenesis virus viruses [DOI] 10.1002/jmv.25866 PMC 바로가기 [Article Type] Research Article
The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic코로나19 숙주 유전학 이니셔티브(COVID-19 Host Genetics Initiative)는 SARS-CoV-2 바이러스 대유행의 감수성과 중증도에서 숙주 유전적 요인의 역할을 밝히기 위한 글로벌 이니셔티브입니다.Policy Published on 2020-05-132022-08-13 Journal: European Journal of Human Genetics [Category] MERS, SARS, 신약개발, 유전자 메커니즘, [키워드] COVID-19 Factor Genetic Genetics research Host initiative pandemic severity Social sciences susceptibility the SARS-CoV-2 virus [DOI] 10.1038/s41431-020-0636-6 PMC 바로가기 [Article Type] Policy
Clinical features of coronavirus disease 2019 (COVID-19) in a cohort of patients with disability due to spinal cord injury Research Published on 2020-05-132022-10-05 Journal: Spinal cord series and cases [Category] SARS, 치료법, [키워드] affecting alteration average delay chest X-ray clinical clinical evolution Clinical severity Cohort cohort analysis cohort of patient conducted coronavirus disease cough COVID-19 COVID-19 infection detect Diagnosis diagnostic Dyspnea exhibited expected feature FIVE General population greater Infection Injury interquartile range male Measures nasal objective Patient patients polymerase chain Radiographic radiological Registered Result RT-PCR setting Seven severity Spain Spinal cord injury sputum samples Symptom System transcriptase was performed [DOI] 10.1038/s41394-020-0288-3 [Article Type] Research
Can Unconventional Immunomodulatory Agents Help Alleviate COVID-19 Symptoms and Severity?Opinion/Hypothesis Published on 2020-05-132022-10-30 Journal: mSphere [Category] COVID-19, MERS, SARS, [키워드] absence acute respiratory syndrome agent Anti-inflammatory antiviral agent Can CCL2 chemokines clinical trial coronavirus COVID-19 COVID-19 symptom CXCL10 disease symptom DNA effective Effectiveness evaluate IL-1 IL-6 immune response immunomodulatory activity Immunomodulatory agent Immunomodulatory agents immunopathological induce Inflammatory Inflammatory cytokine inhibit Interferon alpha low-dose phytocannabinoids Protein respiratory infection SARS Coronavirus SARS-CoV-2 severity Th1 Th1 cytokine Th2 thimerosal Vaccine variety [DOI] 10.1128/mSphere.00288-20 PMC 바로가기 [Article Type] Opinion/Hypothesis
Approaching Otolaryngology Patients During the COVID-19 PandemicResearch Articles Published on 2020-05-122022-10-29 Journal: Otolaryngology--Head and Neck Surgery [Category] COVID-19, MERS, SARS, [키워드] age analyzed Appropriate bleeding Case series Chinese hospital clinics collected comatose Comorbidities coronavirus disease COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 symptom critical condition deaths demographics Dizziness eye Health care worker (HCW) high risk hospital hospitalized COVID-19 patient hospitals Hyposmia implementation Infection infection control Infection Control measures male Mask measure nasal congestion objective Other otitis externa otolaryngologist otolaryngology outcome Outpatient Patient performed Personal protective equipment Personal protective equipment (PPE) PPE preexamination Prevent Protective Protective clothing recommendation Relevance reported Respirator Result SARS-CoV-2 setting severity Shanghai Shenzhen still hospitalized tracheotomy Treatment university were infected were used Wuhan [DOI] 10.1177/0194599820926144 PMC 바로가기 [Article Type] Research Articles
Time-to-Death approach in revealing Chronicity and Severity of COVID-19 across the WorldResearch Article Published on 2020-05-122022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] absence approach China Concordance coronavirus disease country COVID-19 COVID-19 infection death duration of exposure effective elapsed finding France Generalized linear model Germany help information Iran Italy Mortality mortality rate mortality rates outbreak pandemic predict predicted raise Registered selected Seven severity Spain Spread United Kingdom Vaccine was used were used Wuhan, China [DOI] 10.1371/journal.pone.0233074 PMC 바로가기 [Article Type] Research Article
Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 Research Published on 2020-05-122022-10-05 Journal: Nature Medicine [Category] SARS, 치료기술, [키워드] bronchoalveolar Bronchoalveolar lavage fluid CD8+ T cells characterized COVID-19 healthy Immune cell immune characteristics immune microenvironment monocyte-derived macrophage Pathogenesis Patient patients with COVID-19 potential mechanism respiratory severity severity of COVID-19 Single-cell RNA sequencing [DOI] 10.1038/s41591-020-0901-9 [Article Type] Research
Case report: incidental findings of COVID-19 infection on positron emission tomography/computed tomography for staging of a giant gastric gastrointestinal stromal tumor증례 보고: 거대 위장관 기질 종양의 병기 결정을 위한 양전자 방출 단층 촬영/컴퓨터 단층 촬영에서 코로나19 감염의 우발적 발견Case Reports Published on 2020-05-112022-09-01 Journal: The Pan African Medical Journal [Category] MERS, 진단, [키워드] cardiorespiratory clinical symptom Clinical symptoms complement COVID-19 COVID-19 infection Diagnosis discrepancy disease Disease progression early stage FDG-PET gastrointestinal stromal tumor Giant GIST Infection male medical history past medical history positron emission Positron emission tomography radiological severity Stromal tumor tomography Tumor with COVID-19 [DOI] 10.11604/pamj.supp.2020.35.2.23167 PMC 바로가기 [Article Type] Case Reports
Prevalence, Severity and Mortality associated with COPD and Smoking in patients with COVID-19: A Rapid Systematic Review and Meta-AnalysisCOVID-19 환자의 COPD 및 흡연과 관련된 유병률, 심각도 및 사망률: 신속하고 체계적인 검토 및 메타 분석Research Article Published on 2020-05-112022-08-13 Journal: PLoS ONE [Category] COVID-19, Medicine and Health Sciences, MERS, SARS, [키워드] 95% CI 95% confidence interval 95%CI Abstract calculate calculated Case fatality rate caused chronic obstructive chronic obstructive pulmonary disease conducted COPD coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 case COVID-19 in patient COVID-19 infection COVID-19 patients current database eligible Fatality rate greater higher risk inception inclusion criteria independent Infectious disease information item manuscript Meta-analysis Mortality mortality rate mortality risk narrative Newcastle-Ottawa Scale obstructive pulmonary disease Patient Prevalence prevalence rate prevalence rates preventive measure preventive measures pulmonary disease random-effects model Rapid reduce Reporting required Result review risk screened searched severe complication severe complications severe disease severity smoker Smokers Spread systematic reviews the Newcastle-Ottawa Scale [DOI] 10.1371/journal.pone.0233147 PMC 바로가기 [Article Type] Research Article
Association of the insulin resistance marker TyG index with the severity and mortality of COVID-19Original Investigation Published on 2020-05-112022-10-31 Journal: Cardiovascular Diabetology [Category] COVID-19, MERS, [키워드] 95% CI association Cohort confounder coronavirus disease COVID-19 COVID-19 patients death group Deceased diabetes evaluate Glucose hospital increased risk inflammatory factors insulin resistance marker Mild morbidity Mortality outcome Patient patients died patients with COVID-19 Regression Result Severe case severe cases severity significantly significantly higher statistically significant survivor Triglyceride TyG index were used Wuhan [DOI] 10.1186/s12933-020-01035-2 PMC 바로가기 [Article Type] Original Investigation