Clinical and Psychological Impact of COVID-19 Infection in Adult Patients with Eosinophilic Gastrointestinal Disorders during the SARS-CoV-2 OutbreakArticle Published on 2020-06-262022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] adherent age Campania clinical clinical factor clinical impact clinical information Colitis condition coronavirus Corticosteroid COVID-19 COVID-19 infection diagnosed with COVID-19 disease EGID (Eosinophilic gastrointestinal disease) Eosinophilic eosinophilic esophagitis eosinophils esophagitis females gastroenteritis Gastrointestinal gastrointestinal disease Gender Immunosuppression immunosuppressive Impact Infection lockdown measure Most patient nine Occurrence organized Patient patients preventive measure Psychological psychological Impact Quality of life risk SARS-CoV-2 SARS-COV-2 infection Sex steroid study population susceptible the SARS-CoV-2 therapy university Veneto web-based study were recorded [DOI] 10.3390/jcm9062011 PMC 바로가기 [Article Type] Article
Randomised controlled trial comparing efficacy and safety of high versus low Low-Molecular Weight Heparin dosages in hospitalized patients with severe COVID-19 pneumonia and coagulopathy not requiring invasive mechanical ventilation (COVID-19 HD): a structured summary of a study protocolLetter Published on 2020-06-262022-10-29 Journal: Trials [Category] Coronavirus, SARS, [키워드] 1:1 24 hour Administered airway allocation concealment Alpha ambient analysed aneurysms Anticoagulant treatment anticoagulation antiplatelet Arm arterial assigned Atrial fibrillation bleeding bleeding event block size Blood BMI Body Breastfeeding breath calculated Cancer clinical clinically Coagulopathy Concomitant conjunctival Continuous contributed Control control group Controlled trial corpus COVID-19 COVID19 criteria Critical D-dimer D-dimer level Day death defined detect diagnostic discharged disease severity dissemination dosage dose effective Efficacy and safety element enoxaparin Epistaxis EudraCT event events expected fibrinogen level gingival bleeding group Haemoglobin haemoptysis health-care hematemesis hematoma hemodynamic heparin High dose high risk history hospital discharge Hospital stay hospitalized patient hypersensitivity Hypothesis IL-6 Impaired impairing improvement IMV In-hospital indication initiated Inpatient INR internal Intervention intervention group Intra-articular intramuscular invasive Invasive mechanical ventilation involved Italian Italy laboratory parameter LMWH low dose low-molecular weight heparin macroscopic Major major bleeding management Mechanical mechanical ventilation medical intervention Medicine Modena NIV Non-invasive number objective occur Occurrence open label ophthalmic oral anticoagulant outcome oxygen paO2/fiO2 parallel group participant pathology Patient performed Pharyngeal swab plasma Platelet Pneumonia positive pregnancy test Presence pressure Primary outcome prophylactic dose prosthetic protocol random randomisation randomised randomised controlled randomised controlled trial randomization Rate receiving recorded recruited Rectal Bleeding reduce reduction in Registered renal function reported required respiratory risk risk of death Sample size SARS-CoV-2 secondary secure Severe COVID-19 pneumonia severe disease significantly Spontaneous standard oxygen therapy Stata status stratified stroke study drug Study protocol subcutaneously surgical susceptible symptomatic syndrome therapeutic dose therapy thrombocytopenia time transfusion Treatment unfractionated heparin unit Vascular venipuncture Venous Thromboembolism web-based system website weight Withdrawal worsening [DOI] 10.1186/s13063-020-04475-z PMC 바로가기 [Article Type] Letter
GSK-3 Inhibition as a Therapeutic Approach Against SARs CoV2: Dual Benefit of Inhibiting Viral Replication While Potentiating the Immune ResponseImmunology Published on 2020-06-262022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, SARS, [키워드] adaptive Against Analysis Anti-viral CD8+ CD8+: T lymphocyte subsets connection conserved COVID COVID-19 CTL cytolytic drug ENhance function GSK-3 Hypothesis immune response information inhibit inhibition inhibitor knowledge limit mice N protein natural killer NK cell pandemic Phosphorylation protein sequences question reducing reduction in Replication residue response responses SAR SARS-CoV2 SARS-CoV2 infection Serine small molecule inhibitor T-cell T-Cells (or lymphocytes) the N protein Therapeutic approach therapeutic approaches therapy Vaccine viral (or virus) viral infection viral replication virus while [DOI] 10.3389/fimmu.2020.01638 PMC 바로가기 [Article Type] Immunology
The Two Faces of ACE2: The Role of ACE2 Receptor and Its Polymorphisms in Hypertension and COVID-19Review article Published on 2020-06-252022-10-05 Journal: Molecular Therapy [Category] 유전자 메커니즘, [키워드] ACE ACE2 ACE2 protein ACE2 receptor ACEi acute respiratory syndrome angiotensin-converting enzyme 2 angiotensin-converting enzyme inhibitor angiotensin-renin system antihypertensive drugs antihypertensive medication ARB ARBs association binding blood pressure blood pressure homeostasis coronavirus coronavirus disease COVID-19 Critical debatable Deleterious Effectiveness evaluate examined expression face Genetic Genetic variant genetic variants host cell hypertension infected with SARS-CoV-2 Infection involved mechanism modulate modulating mortality rate Patient populations question receptor reducing risk role SARS-CoV-2 susceptibility therapy virus [DOI] 10.1016/j.omtm.2020.06.017 [Article Type] Review article
Predictors of severe or lethal COVID-19, including Angiotensin Converting Enzyme inhibitors and Angiotensin II Receptor Blockers, in a sample of infected Italian citizens감염된 이탈리아 시민의 표본에서 안지오텐신 전환 효소 억제제 및 안지오텐신 II 수용체 차단제를 포함한 심각하거나 치명적인 COVID-19의 예측자Research Article Published on 2020-06-242022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] ACEi age Analysis angiotensin Angiotensin II angiotensin-converting enzyme inhibitors AOR ARB ARBs association blocker Cancer cardiovascular disease cardiovascular diseases case-control study clinical charts COPD COVID-19 COVID-19 severity CVD Deceased diabete diabetes disease disease severity Electronic health records Enzyme inhibitor Gender hypertension hypertensive independent predictor Infection Italian lethal disease male median medication Mild Multivariate analysis Older age Patient Physicians predicted predictor proportion Receptor Blockers renal retrospective SARS-COV-2 infection severe disease severe symptoms Significant subject therapy treated Treatment [DOI] 10.1371/journal.pone.0235248 PMC 바로가기 [Article Type] Research Article
Practical strategies to manage cancer patients during the COVID-19 pandemic: Saudi Oncology Pharmacy Assembly Experts recommendationsOriginal Articles Published on 2020-06-242022-10-29 Journal: Journal of Oncology Pharmacy Practice [Category] COVID-19, [키워드] addressed advanced age applied approach assembly Cancer Cancer center cancer patient Cancer therapy cancer treatment Care changes in conducted contribute coronavirus coronavirus disease COVID-19 COVID-19 outbreak COVID-19 pandemic effort eight expert Frequency Immunosuppressed Implementing Infection knowledge material methodological Modification multiple comorbidities National oncology oncology patient pandemic participant Pharmacy Practitioner recommendation recommendations reduce Result risk risk of COVID-19 SOPA therapy [DOI] 10.1177/1078155220935564 PMC 바로가기 [Article Type] Original Articles
Coronavirus Disease 2019–COVID-19Review Published on 2020-06-242023-06-18 Journal: Clinical microbiology reviews [Category] Fulltext, SARS, [키워드] COVID-19 Diagnosis emerging coronavirus one health SARS-CoV-2 therapy Vaccines [DOI] 10.1128/CMR.00028-20 PMC 바로가기 [Article Type] Review
Class A G Protein-Coupled Receptor Antagonist Famotidine as a Therapeutic Alternative against SARS-CoV2: An In Silico AnalysisArticle Published on 2020-06-242022-10-28 Journal: Biomolecules [Category] COVID-19, [키워드] administration Analysis antagonist Antiviral antiviral drugs Antiviral effect antiviral therapy approach binding affinity catalytic site class clinical trial Combination computational analysis contribute COVID-19 described disease drug effective Effectiveness Famotidine G protein-coupled receptor Gastroesophageal reflux HIV HIV protease inhibitor Human immunodeficiency virus Hydroxychloroquine in silico indicated inhibitors intravenous involved knowledge outcome pandemic parameter Patient pharmacokinetic pharmacological protease Proteases provided reached Replication repurposing respiratory retrospective SARS-CoV2 SARS-CoV2 infection Scientific community the United State therapeutic therapy Treatment virus replication [DOI] 10.3390/biom10060954 PMC 바로가기 [Article Type] Article
Emerging Prevention and Treatment Strategies to Control COVID-19Review Published on 2020-06-232022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] acute respiratory syndrome clinical development Control convalescent plasma coronavirus coronavirus disease COVID-19 death develop Drug repurposing early stage effort Infection less Novel coronavirus pandemic prevention Research SARS-CoV-2 shown Stem cell therapy Strategy therapy Treatment treatment strategy Vaccine vaccine interventions while [DOI] 10.3390/pathogens9060501 PMC 바로가기 [Article Type] Review
Antibodies to SARS-CoV-2 and their potential for therapeutic passive immunizationReview Article Published on 2020-06-232022-10-31 Journal: eLife [Category] COVID-19, SARS, [키워드] antibodies antibody antibody-based therapy benefit clinician COVID-19 COVID-19 pandemic ENhance enzyme event form immunization Immunotherapy infected patients Infection monoclonal antibody plasma PROTECT public health receptor recovered patients S-protein SARS-CoV-2 SARS-CoV-2-infected patient the antibody response therapeutic therapy Vaccine Vaccines virus virus-neutralizing antibody [DOI] 10.7554/eLife.57877 PMC 바로가기 [Article Type] Review Article