General medical publications during COVID-19 show increased dissemination despite lower validationResearch Article Published on 2021-02-022022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] Analysis article articles both group case sery changed Characteristics collected contributing to COVID-19 COVID-19 pandemic cross-sectional dissemination Extracted groups identify Inclusion information less Metrics much higher Non-COVID-19 observational study original pandemic PCA performed principal component analysis Randomized controlled trial Research Result SARS-CoV-2 significantly subset Support [DOI] 10.1371/journal.pone.0246427 PMC 바로가기 [Article Type] Research Article
Homeopathy for Covid-19 in Primary Care: A structured summary of a study protocol for a randomized controlled trial일차 진료에서 Covid-19에 대한 동종 요법: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-02-012022-08-31 Journal: Trials [Category] MERS, 임상, 치료제, [키워드] 1:1 6 hour 6 hours acute respiratory syndrome Adverse adverse events alcohol alternative hypothesis appearance blinded Blinding block randomization bottle Brazil changed changes chest pain clinical trial cough COVID-19 defined dissemination dose double-blind Effectiveness elapsed element emergency services Fever followed by headache Home isolation homeopathic medicine homeopathic medicines Homeopathy hospitalizations identity Influenza Influenza-like symptoms Informed consent investigators measure medication Medicine Medicines Mild mild case mild cases muscle aches network null hypothesis number objective Older outcome Pain participant performed Placebo placebo-controlled positive RT-PCR primary care primary endpoint Primary Health Care protocol randomisation randomised Randomized Randomized controlled trial Randomized Controlled Trial protocol recorded Recovery time recruitment Registered required respiratory Sample size SARS-CoV-2 secondary Severe acute respiratory syndrome shakes sore throat statistician status study medication Study protocol submitted supplementary material Symptom Telemedicine Time to recovery tiredness treatment group Trial two group two groups Unified Health System university website without symptoms [DOI] 10.1186/s13063-021-05071-5 PMC 바로가기 [Article Type] Letter
High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial (CARED-TRIAL)COVID-19 환자의 합병증을 예방하기 위한 고용량 비타민 D 대 위약: 무작위 대조 시험(CARED-TRIAL)을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-02-012022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 24 hour 24 hours Admission age allergy ambient and vitamin D anticonvulsants assessment Asthma Blinding block Blood body mass body mass index breathing ambient air calcium cardiovascular cardiovascular disease carried charge childbearing childbearing age cholecalciferol chronic Chronic kidney disease clinical clinical complications clinical outcomes comparator Complete Complication computer-generated Contact COPD coronary artery bypass grafting country COVID-19 COVID-19 patient COVID-19 patients criteria current death diabete diabetes discharge discretion disease dissemination dose double-blind Effect element enrolled evaluate exclusion exclusion criteria failure first stage FIVE gel Gender grafting Haemodialysis High dose history hospital Hospital admission hospital discharge Hospitalization hypercalcemia hypertension IMPROVE include inclusion criteria Infection Informed consent initiated Intervention invasive invasive or non-invasive ventilation investigator investigator-initiated investigators Kidney disease Life expectancy liver malabsorption management matching placebo mechanical ventilation medication moderate multicentre Myocardial infarction Non-invasive non-invasive ventilation number objective occur Occurrence oral cholecalciferol oral intake Organ failure outcome oxygen oxygen saturation Oxygenation packaged pandemic PaO participant Patient patients performed Pharmacist pharmacological physiological effects Placebo placebo-controlled clinical trial Pneumonia Pragmatic Prevent Primary outcome protocol pulse oximetry random randomised randomised controlled trial randomization randomization ratio Randomized recorded recruited recruitment Registered reported Requirement researcher respiratory Respiratory outcome respiratory outcomes risk routine clinical practice RT-PCR Sample size sarcoidosis SARS-CoV-2 Sepsis sequence sequential design serum calcium Seven stages Standard status stratified study drug study medication Study protocol subject supplementary material total sample size Treatment Trial Trial registration Two-arm valve replacement variable Vitamin D Vitamin D supplementation was used website [DOI] 10.1186/s13063-021-05073-3 PMC 바로가기 [Article Type] Letter
Feasibility of Rapidly Developing and Widely Disseminating Patient Decision Aids to Respond to Urgent Decisional Needs due to the COVID-19 PandemicArticle Published on 2021-02-012023-07-13 Journal: Medical decision making : an international journal [Category] SARS, [키워드] decisional needs development methods dissemination Ottawa Decision Support Framework patient decision aid Shared decision making [DOI] 10.1177/0272989X20979693 PMC 바로가기
Pregnancy and neonatal outcomes in COVID-19: study protocol for a global registry of women with suspected or confirmed SARS-CoV-2 infection in pregnancy and their neonates, understanding natural history to guide treatment and preventionCOVID-19의 임신 및 신생아 결과: 임신 중 SARS-CoV-2 감염이 의심되거나 확인된 여성과 그 신생아의 글로벌 등록을 위한 연구 프로토콜, 치료 및 예방을 위한 자연사 이해Infectious Diseases Published on 2021-01-292022-09-01 Journal: BMJ Open [Category] 진단, [키워드] affected Analysis approval association carried caused Clinical management collected COVID-19 Data collection data set database dissemination Ethics evaluate Evidence evidence of face-to-face contact fetal growth incidence Infection Infectious diseases International linkage Local media memory Middle East respiratory syndrome miscarriage Mortality mother natural history Neonatal Neonate Neonates neonatology observational study obstetrics Outbreaks outcome pandemic Pandemics participant Pregnancy pregnant preterm delivery pseudonymised data public health Rapid recruited reduce registration number Regular required Research Research Ethics respiratory robust SARS-COV-2 infection social media statistical analysis Stillbirth Study protocol syndrome Transmission Treatment vertical transmission website women [DOI] 10.1136/bmjopen-2020-041247 PMC 바로가기 [Article Type] Infectious Diseases
Promising Extracellular Vesicle-Based Vaccines against Viruses, Including SARS-CoV-2Review Published on 2021-01-272022-10-28 Journal: Biology [Category] COVID-19, [키워드] adjuvants Antigen display Antigen presentation antigens Antiviral B cell biogenesis biological processes cell-to-cell communication Characteristics conventional vaccine COVID-19 displaying dissemination DNA Efficiency EVs Exosomes flexible heterogeneous highlighting human cell Immune cell immune responses immunogenic profile Including induce infected cell Infection Intercellular communication limit limitation lipids mRNA overcome presenting Protein Proteins reaction Reactions RNAs Safe SARS-CoV-2 secreted simple spike strong immune response T cell the SARS-CoV-2 therapeutic agents transfer uninfected cell unique Vaccine Vaccine design Vaccines Vesicle Viral antigen Viral protein Viral proteins [DOI] 10.3390/biology10020094 PMC 바로가기 [Article Type] Review
Early use of corticosteroids in non-critical patients with COVID-19 pneumonia (PREDCOVID): a structured summary of a study protocol for a randomised controlled trialCOVID-19 폐렴(PREDCOVID)이 있는 중요하지 않은 환자에서 코르티코스테로이드의 조기 사용: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-01-262022-09-10 Journal: Trials [Category] MERS, 임상, [키워드] 1:1 48 hours adverse event allocation approved ARMS attending physician authors Blinding Care Caregiver Caregivers Child chronic Chronic kidney disease Chronic respiratory failure Composite computer consent form Control Corticosteroids COVID-19 COVID-19 pneumonia cumulative incidence Date Day decrease defined delirium Deterioration dissemination early treatment Efficacy element emergency room evaluate exclusion criteria FiO2 glycemic GRADE grade 3 hospital ICU inclusion criteria Infection infections insulin intensive care interruption Intervention invasive Invasive mechanical ventilation investigator Kidney disease Liver damage Mechanical mechanical ventilation minute nasal nasal cannula not blinded number objective on mechanical ventilation outcome oxygen Oxygen requirements participant Participation Patient patients patients with COVID-19 PCR Pneumonia Pragmatic pragmatic clinical trial Prednisone Pregnancy Primary outcome principal investigator progression protocol random randomised randomised controlled trial Randomized registration number Requirement respiratory Respiratory failure responsibility RT-PCR Sample size secondary Serious Adverse Event Serious Adverse Events Stata statistician status steroid Study protocol submitted supplementary material time Treatment Trial Trial registration urinary tract infection use of corticosteroid usual care venturi mask was used website with COVID-19 [DOI] 10.1186/s13063-021-05046-6 PMC 바로가기 [Article Type] Letter
Predictors of COVID-19 Information Sources and Their Perceived Accuracy in Nigeria: Online Cross-sectional StudyOriginal Paper Published on 2021-01-252022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS, [키워드] 95% CI Accuracy addition Analysis asked Care communication conducted Control COVID-19 COVID-19 pandemic Critical cross-sectional dissemination effective communication ethics committee First wave Health health information infodemic infodemiology information information source Lago less lockdown majority media MOST Nigeria objective Odds ratio organizations pandemic Perceived predictor proportion public health question respondent Result risk Source Stata 15.0 software StataCorp state Teaching university was obtained World Health Organization [DOI] 10.2196/22273 PMC 바로가기 [Article Type] Original Paper
A Missing Link: Engagements of Dendritic Cells in the Pathogenesis of SARS-CoV-2 InfectionsReview Published on 2021-01-232022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, [키워드] acute respiratory syndrome adaptive antiviral cytokines Arm Cell contribute coronavirus coronavirus disease COVID-19 COVID-19 pathogenesis dendritic cells dissemination Engagement function immune cell recruitment immune responses immune system Immunity immunopathology include Inflammatory responses knowledge lymph nodes mechanism missing patients response SARS-CoV-2 SARS-CoV2 subset T cell therapy Tolerance viral disease [DOI] 10.3390/ijms22031118 PMC 바로가기 [Article Type] Review
Prioritizing knowledge translation in low- and middle-income countries to support pandemic response and preparednessCommentary Published on 2021-01-182022-10-31 Journal: Health Research Policy and Systems [Category] Coronavirus, [키워드] activity country COVID-19 pandemic dissemination Evidence-based response Health IMPROVE knowledge Knowledge translation Novel coronavirus organization pandemic pandemic preparedness Pandemics pathway Policy-making promote Research response seeking Support translation Transmission while [DOI] 10.1186/s12961-020-00670-1 PMC 바로가기 [Article Type] Commentary