Shelter from the cytokine storm: Healthy living is a vital preventative strategy in the COVID-19 eraArticle Published on 2022-07-012022-11-16 Journal: Progress in Cardiovascular Diseases [Category] COVID19(2023년), SARS, 변종, [키워드] Admission association Characteristics chronic condition chronic disease Coronavirus disease 2019 COVID-19 COVID-19 infection creating cytokine Cytokine storm death decrease diagnoses Diagnosis diet elicit Health healthy Hospitalization Immunity IMPROVE infected with COVID-19 Infection Inflammation intensive care Measures mechanical ventilation mechanism outcome outcomes pathophysiologic physical activity risk risk factor social distancing the cytokine storm threat vaccination efficacy variant viral infection viral infections [DOI] 10.1016/j.pcad.2021.06.008 PMC 바로가기
Association of BNT162b2 Vaccine Third Dose Receipt With Incidence of SARS-CoV-2 Infection, COVID-19-Related Hospitalization, and Death Among Residents of Long-term Care Facilities, August to October 20212021년 8월부터 10월까지 장기요양시설 입소자 중 SARS-CoV-2 감염, COVID-19 관련 입원 및 사망 발생이 있는 BNT162b2 백신 3차 접종 협회Observational Study Published on 2022-07-012022-09-11 Journal: JAMA Network Open [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] 95% CI 95% CIs adjusted age Analysis association BNT162b2 BNT162b2 vaccine booster dose Care caused Chain Reaction choice cohort study conducted COVID-19 COVID-19 vaccine COVID-19-related death cumulative cumulative incidence cumulative rate delta variant dose effective female follow-up duration follow-up period group hazard hazard ratios Hospitalization hospitalizations HRs immunogenic incidence IQR Kaplan-Meier curves less Long-term care median Mild-to-moderate Mortality multivariable Cox regression Observational cohort study occurred of BNT162b2 Older outcome participant polymerase chain reaction receipt recipient resident reverse transcription Reverse transcription-polymerase chain reaction RT-PCR SARS-CoV-2 SARS-COV-2 infection severe disease Surveillance the mean vaccination Vaccine vaccinee [DOI] 10.1001/jamanetworkopen.2022.19940 PMC 바로가기 [Article Type] Observational Study
Risk factors for progression to acute respiratory failure after casirivimab and imdevimab administration: A retrospective study카시리비맙 및 임데비맙 투여 후 급성 호흡부전으로 진행되는 위험인자: 후향적 연구Article Published on 2022-07-012022-09-12 Journal: Respiratory investigation [Category] 진단, [키워드] Acute respiratory failure administration Admission analyzed antibody C-reactive protein Casirivimab casirivimab/imdevimab Characteristics Chest Chest computed tomography Chest radiograph city coronavirus disease COVID-19 Cycle threshold value detectable develop diabete diabetes Disease progression effective Factor Glucose hemoglobin Hiroshima Hospitalization independent interleukin-6 Logistic regression analysis Lymphocyte count median age monoclonal antibody multivariate Outpatient Patient patients with COVID-19 patients with diabete Pneumonia polymerase chain progressed progression reported Respiratory failure Retrospective study risk factor severe disease significantly therapy treated two group two groups [DOI] 10.1016/j.resinv.2022.04.005 PMC 바로가기 [Article Type] Article
Inhaled ciclesonide for outpatient treatment of COVID-19 in adults at risk of adverse outcomes: a randomised controlled trial (COVERAGE)Randomized Controlled Trial Published on 2022-07-012022-10-04 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 신약개발, 임상, 치료법, [키워드] absence Adults adverse events adverse outcome alleviation of symptoms Analysis ARMS Blood Ciclesonide clinical Comorbidity control arm COVID-19 COVID-19 outpatient criteria Day death died Efficacy Endpoint European Medicines Agency Evidence Evolution Follow-up Hospitalization Hospitalized improvement Inhaled inhaled corticosteroid inhaled corticosteroids intent-to-treat interim analysis interquartile range involved median age median time men Open-label Other outcome Outpatient outpatients Oxygen therapy parameter participant patients with COVID-19 primary efficacy endpoint primary endpoint randomised controlled trial Randomized controlled trial Randomly reached reducing reported risk risk factor RT-PCR Safety Monitoring Board scale secondary sustained Symptom the WHO Treatment Trial women worsening [DOI] 10.1016/j.cmi.2022.02.031 PMC 바로가기 [Article Type] Randomized Controlled Trial
COVID-19 death and kidney disease in a multiracial Asian countryObservational Study Published on 2022-07-012022-10-05 Journal: Nephrology (Carlton, Vic.) [Category] 임상, [키워드] Absolute lymphocyte count Acute kidney injury admitted to ICU age AKI Asian CFR Chinese Chronic kidney disease CKD conducted cough country covariate COVID-19 COVID-19 infection COVID-19 patients death Diabetes Mellitus Dyspnea Ethnicity Factor Fatality rate Fever group help Hospitalization hospitalized COVID-19 patient identify IMPROVE increased risk kidney Kidney disease male management Mortality multicentre outcome Patient predictor Racial required risk Risk factors severity significantly Symptom understanding Ventilation [DOI] 10.1111/nep.14045 PMC 바로가기 [Article Type] Observational Study
Serum hemato-immunological biomarkers associated with increased COVID-19 mortality in the Latino population라틴계 인구에서 COVID-19 사망률 증가와 관련된 혈청 혈액 면역학적 바이오마커Observational Study Published on 2022-07-012022-09-11 Journal: Biomarkers in Medicine [Category] MERS, 바이오마커, 임상, 진단, [키워드] Biomarker Comorbidity COVID-19 COVID-19 hospitalization COVID-19 mortality COVID-19 patient death followed by Hospitalization increased mortality independent Inflammatory inflammatory biomarkers Latino leukocyte lymphocyte median age men moderate disease Mortality neutrophil Neutrophil-to-lymphocyte ratio obesity overweight patients Platelet predictor Prognostic factor Prognostic factors pulmonary damage raised Retrospective study Serum inflammatory biomarkers severe disease [DOI] 10.2217/bmm-2022-0056 PMC 바로가기 [Article Type] Observational Study
Elevated SARS-CoV-2 in peripheral blood and increased COVID-19 severity in American Indians/Alaska NativesObservational Study Published on 2022-07-012023-07-09 Journal: Experimental Biology and Medicine [Category] COVID19(2023년), [키워드] COVID-19 Hospitalization intensive care race/ethnicity SARS-CoV-2 Viral load [DOI] 10.1177/15353702221091180 PMC 바로가기 [Article Type] Observational Study
Whole-genome sequencing reveals host factors underlying critical COVID-19전체 게놈 시퀀싱은 중요한 COVID-19의 기저에 있는 숙주 요인을 밝힙니다Article Published on 2022-07-012022-09-11 Journal: Nature [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, 유전자 메커니즘, 임상, 진단, 치료기술, 치료제, [키워드] Adhesion Molecule Antigen association associations ATP11A BCL11A caused CD209 Coagulation coagulation factor Colocalization Control COVID-19 Critical Critical care Critical disease Critical illness Critically ill disease disease severity Evidence expression Factor failure FUT2 Gene Expression Genetic variation genetics Genome genomes GenOMICC Hospitalization Host ICAM5 identify IL10RB Immune-mediated increased expression independent individual infection with SARS-CoV-2 inflammatory lung injury influence interferon intravascular coagulation involved leucocyte life-threatening Lung injury mechanism mechanisms membrane mendelian randomization MUC1 mucin myeloid cell pathophysiology PLSCR1 provide pulmonary inflammation reduced replicate reveal SELE Sequencing significantly Support targets transcriptome-wide underlying disease variant variants Viral viral replication whole-genome sequencing [DOI] 10.1038/s41586-022-04576-6 PMC 바로가기 [Article Type] Article
Data-driven case fatality rate estimation for the primary lineage of SARS-CoV-2 in Poland폴란드에서 SARS-CoV-2의 1차 계통에 대한 데이터 기반 사례 치사율 추정Article Published on 2022-07-012022-09-11 Journal: Methods (San Diego, Calif.) [Category] COVID19(2023년), SARS, 변종, [키워드] accompany age Analysis Care Case fatality rate case fatality rates CFR Comorbidities Comorbidity competing Contact Contact tracing COVID-19 COVID-19 infection COVID-19 mortality expected Factor fatality Fatality rate group Health Health care Health care system Hospitalization Hospitalized increased mortality Lineage management Medical care Mortality Mortality in Poland mortality risk multivariate analyses Multivariate analysis original Original SARS-CoV-2 lineage. outbreak pandemic Pandemics Poland provide recent reducing mortality risk SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 variant SARS-CoV-2 variants selected Sex significantly subpopulation variables [DOI] 10.1016/j.ymeth.2022.01.006 PMC 바로가기 [Article Type] Article
A historical cohort study to investigation of statins safety in COVID-19 hospitalized patientsResearch article Published on 2022-07-012022-10-05 Journal: Thérapie [Category] COVID19(2023년), SARS, 신약개발, [키워드] 95% CI addition Admission age anti-inflammatory properties association cardiovascular diseases Chronic kidney disease CKD cohort study condition conditions Corticosteroids COVID COVID-19 COVID-19 infected patients COVID-19 patient COVID19 decrease diabetes evaluated groups hospital Hospitalization hospitalized COVID-19 patients hospitalized patient hypertension ICU ICU admission implementation Inflammatory marker inhibitor intensive care Mortality mortality rate notable Odds ratio outcome proportion Result SARS-CoV-2 severity Sex shown significant difference significantly single-center statin statins statistical analysis Statistics stroke Tehran variable was performed [DOI] 10.1016/j.therap.2021.10.006 [Article Type] Research article