Changes to anti-JCV antibody levels in a Swedish national MS cohortArticle Published on 2013-11-012023-06-02 Journal: Journal of neurology, neurosurgery, and psychiatry [Category] 두창, [키워드] Infectious diseases multiple sclerosis neurovirology Virology. [DOI] 10.1136/jnnp-2012-304332 PMC 바로가기
Analysis of the Host Transcriptome from Demyelinating Spinal Cord of Murine Coronavirus-Infected MiceResearch Article Published on 2013-09-182022-10-28 Journal: PLoS ONE [Category] Coronavirus, [키워드] accompanied accompany Antigen presentation approach Central nervous system changes in CNS contribute CORD cytokine DAP12 debris clearance demyelinating Demyelination disease Diseases Evidence expression Factor found Gene High-throughput sequencing highlight Host host antiviral response host transcriptome immune infiltration Immune-mediated increased expression induce Infected Infection Inflammation information involved knowledge lipid metabolism lipid transport Macrophage MHV microglia mouse hepatitis virus multiple sclerosis neurodegenerative pathway persistent infection RNA-Seq several gene spinal Support These data transcriptional change TREM2 upregulated viral infection [DOI] 10.1371/journal.pone.0075346 PMC 바로가기 [Article Type] Research Article
Microglia Play a Major Role in Direct Viral-Induced DemyelinationResearch Article Published on 2013-06-202022-10-31 Journal: Clinical and Developmental Immunology [Category] Coronavirus, [키워드] activate activated Activation Acute inflammation Antigen presentation APC calcium-binding protein cause cellular Central nervous system changes in characteristic chronic inflammation CNS Culture current demonstrated Demyelination Direct evidenced Ex vivo function in vitro increased expression infect Infected Infection Inflammatory Injury involved Major membrane MHV microglia microglial morphology mouse hepatitis virus multiple sclerosis myelin sheath Neonatal Neurological disease neurotropic performed phagocytosis Population Postinfection previous study Proteins role subsequent suggested turn [DOI] 10.1155/2013/510396 PMC 바로가기 [Article Type] Research Article
A Genome-Wide Integrative Genomic Study Localizes Genetic Factors Influencing Antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1)게놈 전체에 걸친 통합 게놈 연구는 엡스타인-바 바이러스 핵 항원 1(EBNA-1)에 대한 항체에 영향을 미치는 유전적 요인을 국소화합니다.Research Article Published on 2013-01-102022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] a major Adult adverse outcome adverse outcomes analysis Analysis antibody antibody levels Antigen approach association Author Autoimmune disorders best Burkitt lymphoma Cancer cancers Candidates chromosome chromosome 6 concerning dataset disease Disease progression DQB1 DRB1 EBV Epstein Barr virus Epstein-Barr virus Evidence evidence of examined expression data Factor family members focus foreign antigen foreign antigens found Gene Gene Expression Genetic genetic factors Genome HLA HLA locus HLA-DQB1 HLA-DRB1 Hodgkin lymphoma Host human leukocyte antigen IgG antibodies IgG antibody immune function immune system independent individual infect Infected Infection infectious Infectious disease infectious mononucleosis investigated involved joint leukocyte linkage loci locus lupus erythematosus lymphocyte lymphoproliferative disorders malignancies malignancy measure mechanism MHC class MHC class II multiple sclerosis nasopharyngeal lymphoma not found nuclear overlap P -value pathogen Pathogens prevalent provide regulate related replicated Research severe complication severe complications severe disease significantly SNP SNPs susceptibility susceptibility loci systemic lupus erythematosus T cells virus was obtained [DOI] 10.1371/journal.pgen.1003147 PMC 바로가기 [Article Type] Research Article
Multiple Sclerosis: The Role of Cytokines in Pathogenesis and in TherapiesReview Published on 2012-10-192023-08-30 Journal: International Journal of Molecular Sciences [Category] E형 간염, [키워드] Cytokines interferons (IFNs) interleukin-17 (IL-17) multiple sclerosis T helper cells (Th) [DOI] 10.3390/ijms131013438 PMC 바로가기 [Article Type] Review