Evaluation of droplet digital PCR for quantification of SARS-CoV-2 Virus in discharged COVID-19 patients퇴원한 코로나19 환자에서 SARS-CoV-2 바이러스 정량을 위한 비말 디지털 PCR 평가Research Paper Published on 2020-11-152022-09-01 Journal: Aging (Albany NY) [Category] SARS, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition analyzed be positive blind clinical sample clinical samples coronavirus coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 patient cutoff value detect diagnosis of COVID-19 Digital digital PCR discharge discharged discharged criteria discharged patient discharged patients droplet droplet digital PCR eight gold gold standard help IMPROVE in some infected patient Inpatient Misdiagnosis outbreak Patient PCR positive positive sample qPCR quantification Quantitative quantitative real time PCR real time real time PCR reduce relapsing respiratory retained SARS-CoV-2 selected Sensitivity and specificity significantly Spread synchronous Viral Viral load virus [DOI] 10.18632/aging.104020 PMC 바로가기 [Article Type] Research Paper
Accuracy of Conventional and Machine Learning Enhanced Chest Radiography for the Assessment of COVID-19 Pneumonia: Intra-Individual Comparison with CTArticle Published on 2020-11-062022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Accuracy acquisition assessment calculated confidence level consolidation control group Conventional COVID-19 COVID-19 patient Critical care CXR Diagnosis diagnostic disease enhanced evaluate GGO GGOs ground-glass opacity imaging CT/MRI independent infection control Interpretation machine learning median age moderate Patient Pneumonia polymerase chain quantification Radiography respiratory infection sensitivity significant differences specificity viral infection was used with COVID-19 [DOI] 10.3390/jcm9113576 PMC 바로가기 [Article Type] Article
Pushing beyond specifications: Evaluation of linearity and clinical performance of the cobas 6800/8800 SARS-CoV-2 RT-PCR assay for reliable quantification in blood and other materials outside recommendationsArticle Published on 2020-11-012023-07-02 Journal: Journal of Clinical Virology [Category] SARS, [키워드] Cobas 6800 COVID-19 molecular diagnostics quantification RT-PCR SARS-CoV-2 [DOI] 10.1016/j.jcv.2020.104650 PMC 바로가기
CoroNet: A deep neural network for detection and diagnosis of COVID-19 from chest x-ray imagesResearch article Published on 2020-11-012022-10-05 Journal: Computer methods and programs in biomedicine [Category] SARS, 치료기술, [키워드] Accuracy automatically Bacterial Chest Chest X-ray images claimed clinician Convolutional neural network coronavirus country COVID COVID-19 COVID-19 case COVID-19 cases COVID-19 infection COVID-19 pandemic dataset deep deep learning detect Diagnosis diagnosis of COVID-19 Follow-up indicate learning methodology network model Neural objective Pneumonia Pneumonia bacterial Pneumonia viral Practitioner Precision produced quantification radiologist recall resources Result Spread tested training data Wuhan, China X-ray [DOI] 10.1016/j.cmpb.2020.105581 [Article Type] Research article
Sample adequacy controls for infectious disease diagnosis by oral swabbing구강 면봉으로 감염병 진단을 위한 샘플 적합성 관리Research Article Published on 2020-10-302022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] applied can not cell type collected Control COVID-19 Cq values Cutoff detect diagnosing Diagnosis DNA Ebola evaluated exhibited expected healthy human cell human cells Infectious disease Infectious diseases mitochondrial mitochondrial DNA mouth negative control negative controls Non-invasive not used oral oral cavity oral microbiota oral swab oral swabs Paired analysis PCR qPCR quantification quantitative PCR representing SACs Sample Sensitivity and specificity South Africa Streptococcus species Streptococcus specy subjects Swab swabbing swabs target cell TB patient TB patients tongue Tuberculosis volunteers [DOI] 10.1371/journal.pone.0241542 PMC 바로가기 [Article Type] Research Article
Computed tomography semi-automated lung volume quantification in SARS-CoV-2-related pneumoniaImaging Informatics and Artificial Intelligence Published on 2020-10-302022-10-31 Journal: European Radiology [Category] COVID-19, MERS, SARS, [키워드] affected Algorithm Analysis artificial intelligence C-reactive protein calculated Chest Computed tomography, X-ray concerning consolidation correlated CRP enrolled evaluate expressed functional GGO HCO Infection, coronavirus invasive ventilation laboratory data laboratory parameter lung Lung CT lung involvement Lung volume lung volume measurements lung volumes lymphocyte neutrophil objective outcome outcomes P / F paO2/fiO2 parameter pathological Patient Platelet Pneumonia Point quantification Quantitative Result SARS-CoV-2 severity significant difference significantly tomography Total lung volume Ventilated Volume WBC White blood cell [DOI] 10.1007/s00330-020-07271-0 PMC 바로가기 [Article Type] Imaging Informatics and Artificial Intelligence
Cerebrospinal fluid lipidomic biomarker signatures of demyelination for multiple sclerosis and Guillain–Barré syndromeArticle Published on 2020-10-272022-10-04 Journal: Scientific Reports [Category] 바이오마커, [키워드] affecting Analysis Biomarker biomarker signature Central nervous system changes in characteristic complement Concentration Control controls CSF demyelinating disorder Demyelination diagnostic diagnostic biomarker Diseases Guillain–Barrè syndrome Lipidomics mass spectrometry molecular Multiple multiple sclerosis nervous system Neurological diseases Neurological disorder Neurological disorders Patient positive correlation Protein quantification sensitivity syndrome upregulated was used [DOI] 10.1038/s41598-020-75502-x PMC 바로가기 [Article Type] Article
Sensitive detection and quantification of SARS-CoV-2 by multiplex droplet digital RT-PCR다중 액적 디지털 RT-PCR을 통한 SARS-CoV-2의 민감한 검출 및 정량화Original Article Published on 2020-10-262022-09-10 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] COVID-19 patients criteria ddPCR detectable develop dilution series DNA gold gold standard GUSB housekeeping gene MONITOR monitoring mRNA multiplex Multiplex assay not affected nucleic acid patients quantification RdRP RNA robust RPP30 RT-PCR RT-PCR assay SARS-CoV-2 SARS-CoV-2 RNA sensitive sensitivity transcript Validity Viral Viral load viral loads Viral RNA was used water [DOI] 10.1007/s10096-020-04076-3 PMC 바로가기 [Article Type] Original Article
Psychological impact of mass quarantine on population during pandemics—The COVID-19 Lock-Down (COLD) studyResearch Article Published on 2020-10-222022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] adopted Anxiety anxiety disorders baseline COVID-19 cross Depression depressive detrimental disorder eight finding General population help highest implementation incidence increase in India lockdown mandatory modify Prevalence Psychological Psychological distress psychological health psychological Impact quantification quarantine questionnaire reported significantly higher Stress variable [DOI] 10.1371/journal.pone.0240501 PMC 바로가기 [Article Type] Research Article
Rapid response flow cytometric assay for the detection of antibody responses to SARS-CoV-2SARS-CoV-2에 대한 항체 반응 검출을 위한 신속한 반응 유세포 분석법Original Article Published on 2020-10-202022-09-10 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] 293T cell ACE-2 adopted angiotensin antibodies Antibody Response Antibody responses approach blueprint CLIA coronavirus detect diagnostic early phase ELISA evaluated expressing flow cytometric flow cytometry highest IgG and IgM IgM antibody Laboratory nucleic acid pandemic patient sera PCR-confirmed provide quantification Quantitative Rapid robust SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2-infected patients SARS-CoV-2-specific antibodies sensitivity sera Serological assay serological test Serological tests serology specific antibodies specificity specimen Spike protein Spike-specific antibody spike-specific antibody response Spike-specific antibody responses Spread variant Viral viral infection viral infections were used while Zoonotic coronavirus [DOI] 10.1007/s10096-020-04072-7 PMC 바로가기 [Article Type] Original Article