Plasmodium falciparum in Asymptomatic Immigrants from Sub-Saharan Africa, Spain아프리카 사하라 이남 지역에서 온 무증상 이민자에서 발견된 플라스모디움 팔시파룸, 스페인Letter to the Editor Published on 2012-02-012024-08-14 Journal: Emerging Infectious Diseases [Category] 말라리아, [키워드] Africa asymptomatic infections Immigrants malaria parasites public health Screening Spain sub-Saharan Africa [DOI] 10.3201/eid1802.111283 PMC 바로가기 [Article Type] Letter to the Editor
A −436C>A Polymorphism in the Human FAS Gene Promoter Associated with Severe Childhood MalariaA −436C>심각한 아동기 말라리아와 관련된 인간 FAS 유전자 프로모터의 다형성Research Article Published on 2011-05-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] 95% confidence interval A allele a major activated affected allele Analysis Anemia Apoptosis applied assigned association Author carried Case-control caused CD69 Cell cell surface receptor cerebral malaria childhood children Community compared complex interplay complications Control Donor ENCODE Endemic Express expression FACS analysis FAS fatality found functional Genetic variant genetic variants genetics Health healthy individual help heterozygote homozygote homozygous Human Human genetics immune regulation immune response immune responses increased expression individual Infection investigated involved life-threatening locus lymphocyte Lymphocytes malaria molecule mononuclear cell mononuclear cells naïve nucleotide Occurrence Odds ratio outcome Pediatric case Peripheral blood Peripheral blood mononuclear cells phenotypic Plasmodium Plasmodium falciparum predisposition programmed cell death promoter promoter region proportion PROTECT Protective protective immune response Replication risk severe severe malaria significantly significantly higher Single nucleotide variant sub-Saharan Africa subgroup surface receptor susceptibility susceptible syndrome T-lymphocyte the disease Transmission dynamics variant West [DOI] 10.1371/journal.pgen.1002066 PMC 바로가기 [Article Type] Research Article
Field-Caught Permethrin-Resistant Anopheles gambiae Overexpress CYP6P3, a P450 That Metabolises Pyrethroids현장에서 포착된 퍼메트린 내성 Anopheles gambiae CYP6P3, 피레스로이드를 대사하는 P450 과발현Research Article Published on 2008-11-282022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] A. gambiae adaptive adaptive mechanism adaptive mechanisms Alpha alpha-cyano Anopheles gambiae anopheline mosquitoes Author bioassays compounds Critical CYP6P3 cytochrome P450 detect disease spread Efficacy ENCODE enzyme Enzymes Evolution facilitate found Frequency Gene Gene Expression Genetic Health health problem identify individual insect insecticide insecticides Insects involved lead low frequencies malaria malaria vector malaria vector control mechanism Messenger RNA Metabolic resistance metabolise Molecular assay molecular mechanism molecular mechanisms MONITOR natural selection overexpressed P450 pesticide pesticides phenotyped populations public health pyrethroid Pyrethroids receiving recessive allele reducing resistance significantly sub-Saharan Africa Survivors sustainability trait transcript level translated Transmission undergo [DOI] 10.1371/journal.pgen.1000286 PMC 바로가기 [Article Type] Research Article
Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children플라스모디움 팔시파룸에 감염된 적혈구 표면에 대한 반응 실패는 아프리카 어린이들 사이에서 임상 말라리아에 대한 취약성을 예측합니다.Article Published on 2008-10-012024-08-26 Journal: International Journal for Parasitology [Category] 말라리아, [키워드] Antibody responses children Epidemiology immunology malaria Plasmodium falciparum sub-Saharan Africa susceptibility [DOI] 10.1016/j.ijpara.2008.03.009 PMC 바로가기 [Article Type] Article