symptomatic – Page 45 – Communicable Diseases Research

Prolonged viral shedding of SARS-CoV-2 and related factors in symptomatic COVID-19 patients: a prospective study

Research

Published on 2021-12-272022-10-28
Journal: BMC Infectious Diseases [Category] COVID-19, SARS,

COVID-19 vs. Classical Myocarditis Associated Myocardial Injury Evaluated by Cardiac Magnetic Resonance and Endomyocardial Biopsy

Cardiovascular Medicine

Published on 2021-12-242022-10-31
Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19,

[키워드] acute SARS-CoV-2 infection baseline biopsy cardiac cardiac function chronic inflammation clinical care CMR Cohort COVID-19 COVID-19 infection COVID-19 patient criteria dysfunction eight EMB Evidence exhibited Follow-up form functional global pandemic healthy volunteer histological impairment Inflammation Lake Louise Criteria LLC magnetic resonance imaging Mild moderate disease molecular analysis Myocardial myocardial injury myocarditis nine Non-COVID-19 non-COVID-19 patient oedema Patient patients with COVID-19 reduced resonance SARS-COV-2 infection serious complication severe disease Symptom symptomatic the disease the WHO ventricular viral infection was performed
[DOI] 10.3389/fcvm.2021.737257 PMC 바로가기 [Article Type] Cardiovascular Medicine

Early Remdesivir to Prevent Progression to Severe Covid-19 in Outpatients

외래 환자에서 중증 코로나19로의 진행을 예방하기 위한 조기 렘데시비르

Randomized Controlled Trial

Published on 2021-12-222022-09-25
Journal: The New England Journal of Medicine [Category] Fulltext, SARS, 신약개발, 임상, 진단, 치료제,

[키워드] 95% CI 95% confidence interval Adverse adverse event age assigned Clinical outcome condition conducted coronavirus disease Course death Diabetes Mellitus died Disease progression dose double-blind efficacy end point end point EudraCT event hazard ratio high risk Hispanic Hospitalization hypertension IMPROVE Intravenous remdesivir Latinx lower risk Medical conditions obesity occurred Outpatient Patient patients hospitalized Placebo placebo-controlled trial Prevent progression randomization Randomized Randomly receive Remdesivir Result risk factor safety profile symptom onset symptomatic the patient the placebo group women
[DOI] 10.1056/NEJMoa2116846 PMC 바로가기 [Article Type] Randomized Controlled Trial

Lessons learnt from the first large outbreak of COVID-19 in health-care settings in Tasmania, Australia

Covid-19

Published on 2021-12-222022-10-28
Journal: Western Pacific Surveillance and Response Journal [Category] COVID-19, MERS, SARS,

Clinical, Virological, Immunological, and Genomic Characterization of Asymptomatic and Symptomatic Cases With SARS-CoV-2 Infection in India

인도에서 SARS-CoV-2 감염이 있는 무증상 및 무증상 사례의 임상, 바이러스, 면역 및 게놈 특성 분석

Cellular and Infection Microbiology

Published on 2021-12-212022-09-11
Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 유전자 메커니즘, 치료법,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Analysis antibody Asymptomatic asymptomatic and symptomatic patients asymptomatic patients biochemical biochemical parameter Biochemical parameters C-reactive protein carried caused CD40L changes in characterization circulating antibodies circulating antibody clinical collected Comorbidities contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRP cytokine Cytokines D614G mutation determined by develop diabetes disease disease control disease severity effective Efficiency elevated ferritin genomic global pandemic hospitalized patient IFN-α2 IgA IgG IgM IL-1 IL-10 IL-15 IL-1α IL-6 IL-8 immunological implementation in viral India Infection IP-10 isolate Lactate lactate dehydrogenase LDH mDC Mutation no significant difference nucleocapsid protein Nucleocapsid proteins ORF1ab ORF3a ORF8 Oropharyngeal pathophysiology Patient plasma respiratory Result RT-PCR Sample SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 patient SARS-CoV-2 patients serum serum sample serum samples Seven severe acute respiratory syndrome Coronavirus severe SARS severe SARS-CoV-2 SGOT SGPT Spike protein symptomatic Symptomatic patients treatment regimen two groups two patients type 2 diabete type 2 diabetes Viral viral infection Viral load viral strain viral strains Virological virus replication was determined were assessed Whole-genome sequence whole-genome sequencing
[DOI] 10.3389/fcimb.2021.725035 PMC 바로가기 [Article Type] Cellular and Infection Microbiology

Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blockers, and Outcomes in Patients Hospitalized for COVID-19

Observational Study

Published on 2021-12-212022-10-05
Journal: Journal of the American Heart Association [Category] 임상,

[키워드] 95% CI ACE ACE inhibitors ACEi/ARB adjusted hazard ratio Affect Angiotensin II angiotensin receptor blocker Angiotensin receptor blockers angiotensin-converting enzyme 2 angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitors association biomarkers of inflammation blood pressure C-reactive protein cell entry receptor clinical COVID-19 COVID‐19 death deaths dialysis dose examined Hospitalization In-hospital In-hospital death inclusion criteria Inflammation lower risk Measures mechanical ventilation modulating Mortality multivariable analysis need for dialysis outcome outcomes Patient patients hospitalized receptor Registration required Result SARS-CoV2 serum creatinine symptomatic thought Treatment Trial Ventilation
[DOI] 10.1161/JAHA.121.023535 PMC 바로가기 [Article Type] Observational Study

Acute respiratory infection symptoms and COVID-19 testing behaviour: results based on South Australian health surveys

급성 호흡기 감염 증상 및 COVID-19 검사 행동 : 남호주 건강 조사를 기반으로 한 결과

Research

Published on 2021-12-202022-09-01
Journal: BMC Public Health [Category] SARS, 진단, 치료기술,

[키워드] Acute respiratory infection age ARI Australian Birth chronic disease Chronic diseases Community coronavirus Coronavirus testing cough coughing COVID-19 COVID-19 testing COVID-19 transmission cross-sectional Descriptive statistics detect disease Early detection Factor Gender groups Health healthcare higher odd higher odds higher risk household size identify IMPROVE Intervention mental health multivariable logistic regression multivariable logistic regression models Nurse Older age Participants population level population survey Prevalence Psychological distress reported reported symptom respiratory respiratory infection Result risk factor Risk factors runny nose seeking sore throat South subgroup subgroups Surveillance Symptom symptomatic Symptoms Syndromic surveillance tested Torres Strait variables were used
[DOI] 10.1186/s12889-021-12359-3 PMC 바로가기 [Article Type] Research

Impact of potential modifications to Alzheimer’s disease clinical trials in response to disruption by COVID-19: a simulation study

COVID-19에 의한 혼란에 대한 반응으로 알츠하이머 병 임상 시험에 대한 잠재적 수정의 영향 : 시뮬레이션 연구

Research

Published on 2021-12-202022-09-10
Journal: Alzheimer's Research & Therapy [Category] SARS, 치료기술,

[키워드] accounted adaptive affected Alzheimer Alzheimer disease Alzheimer’s disease Analysis assessments biases change changes changes in Changing clinical trial clinical trials completion COVID-19 COVID-19 pandemic datasets detect disease Disease modification Effect effect size Enrollment examined expected idea Impact investigator investigators linear maintain Mild cognitive impairment Modification outcome outcomes pandemic performed randomized clinical trial RCT RCTs Result risk Simulation Simulations Sponsor Statistical power Support symptomatic Symptomatic treatment threat Threats Treatment treatment period Trial trials Validity was determined
[DOI] 10.1186/s13195-021-00938-w PMC 바로가기 [Article Type] Research

Case Report: Clinical Management of a Patient With Metastatic Non-Small Cell Lung Cancer Newly Receiving Immune Checkpoint Inhibition During Symptomatic COVID-19

증례 보고: 코로나19 증상이 있는 동안 면역 체크포인트 억제를 새로 받은 전이성 비소세포폐암 환자의 임상 관리

Case Reports

Published on 2021-12-202022-09-12
Journal: Frontiers in Immunology [Category] SARS, 진단,

[키워드] activated ambulatory patient Analysis anti-cancer treatment anti-PD1 antiviral immunity blockade CD4 CD8 cellular change clinical Corticosteroid Course COVID-19 CT scan Effect feasible Follow-up healthy High-dose Hospitalized humoral immune response IgG immune checkpoint Immunotherapy inhibition initiated lesion lung cancer male malignancy management metastatic Neutralizing NSCLC Patient PD1 Pembrolizumab Pneumonia Pneumonitis presenting Radiographic SARS-CoV-2 SARS-CoV-2 clearance SARS-COV-2 infection serum sustained symptomatic T cell Tfh the patient treatment initiation worsened
[DOI] 10.3389/fimmu.2021.798276 PMC 바로가기 [Article Type] Case Reports

Infection With the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta Variant Is Associated With Higher Recovery of Infectious Virus Compared to the Alpha Variant in Both Unvaccinated and Vaccinated Individuals

중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 델타 변이형 감염은 백신 접종을 받지 않은 사람과 백신을 맞은 사람 모두에서 알파 변이형에 비해 감염성 바이러스의 더 높은 회복률과 관련이 있습니다

Major Article

Published on 2021-12-182022-09-10
Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 진단, 치료제,

[키워드] (alpha acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha Alpha variant anti-SARS-CoV-2 antibody Antiviral B.1.1.7 B.1.617.2 breakthrough infections Capital Capital Region Cell culture circulating clinical chart Cohort Comorbidities coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 correlated COVID-19 cycle threshold Delta delta variant disease severity greater transmissibility groups IgG IgG levels Immunoglobulin Immunoglobulin G increase in Increases increases in individual Infection infections Infectious virus Lineage Local nasal predominant Region respiratory Result SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 lineage severe acute respiratory syndrome Coronavirus significant increase significantly higher specimens symptomatic the median vaccinated individual vaccinated individuals vaccination variant variants Viral Viral RNA virus VoC Whole genome sequencing
[DOI] 10.1093/cid/ciab986 PMC 바로가기 [Article Type] Major Article