COVID-19: Oxidative Preconditioning as a Potential Therapeutic ApproachReview Published on 2020-11-052023-07-01 Journal: ACS chemical neuroscience [Category] SARS, [키워드] Antiviral CNS COVID-19 oxidative stress Preconditioning SARS-CoV-2 [DOI] 10.1021/acschemneuro.0c00453 PMC 바로가기 [Article Type] Review
Pirfenidone: A novel hypothetical treatment for COVID-19피르페니돈: COVID-19에 대한 새로운 가상 치료제Article Published on 2020-11-012022-08-31 Journal: Medical Hypotheses [Category] 신약개발, 유전자 메커니즘, 치료법, [키워드] ACE acute respiratory distress acute respiratory distress syndrome adverse effects angiotensin angiotensin converting enzyme Angiotensin converting enzyme receptor Apoptosis approved ARDS Cell COVID-19 COVID-19 patients cytokine Cytokine storm decrease distress downregulate expression fibrosis hypothetical idiopathic Idiopathic pulmonary fibrosis Inflammation inhibit Invasion IPF kill majority mechanism mechanism of action Mild mild to moderate mild to moderate disease moderate disease morbidity Mortality multiorgan failure oxidative stress pathophysiology Patient patients with COVID-19 Pirfenidone pneumocyte Pneumocytes PROTECT pulmonary pyridone receptor respiratory distress Respiratory distress syndrome syndrome Treatment treatment for COVID-19 treatment of COVID-19 patients [DOI] 10.1016/j.mehy.2020.110005 PMC 바로가기 [Article Type] Article
What impact of air pollution in pediatric respiratory allergic diseasesArticle Published on 2020-11-012023-07-12 Journal: Pediatric allergy and immunology : official public [Category] SARS, [키워드] Air pollution Asthma oxidative stress Particulate matter respiratory allergic disease. SARS-CoV-2 [DOI] 10.1111/pai.13362
Deletion of the lon gene augments expression of Salmonella Pathogenicity Island (SPI)-1 and metal ion uptake genes leading to the accumulation of bactericidal hydroxyl radicals and host pro-inflammatory cytokine-mediated rapid intracellular clearance론 유전자의 삭제는 살모넬라 병원성 섬( SPI)-1 및 금속 이온 흡수 유전자의 발현을 증가시켜 박테리아 살균성 하이드록실 라디칼과 숙주의 염증성 사이토카인 매개 빠른 세포내 제거의 축적을 초래한다.Article Published on 2020-11-012024-08-21 Journal: Gut Microbes [Category] 살모넬라증, [키워드] Cytokines Lon protease metal ion oxidative stress Salmonella
Short hairpin RNA attenuates liver fibrosis by regulating the PPAR‑γ and NF‑κB pathways in HBV‑induced liver fibrosis in miceArticle Published on 2020-11-012023-06-13 Journal: International journal of oncology [Category] B형 간염, [키워드] Liver fibrosis nuclear factor‑κB oxidative stress peroxisome proliferator‑activated receptor signaling pathway quantitative proteomics [DOI] 10.3892/ijo.2020.5125 PMC 바로가기
An overview of the pathogenic mechanisms involved in severe cases of COVID-19 infection, and the proposal of salicyl-carnosine as a potential drug for its treatmentResearch article Published on 2020-11-012022-10-05 Journal: European journal of pharmacology [Category] 유전자 메커니즘, 치료법, [키워드] Anti-inflammatory anti-inflammatory properties antioxidant antiplatelet Aspirin caused concerning COVID-19 COVID-19 infection COVID-19 patient damage described develop drug Effects Factor hypoxia Inflammation involved Ischemia lung dysfunction mechanism Multiple organ organ damage Organ failure outcome oxidative stress pathogenic mechanism Patient patients with COVID-19 Research Salicyl-carnosine Severe case small blood vessel thrombosis tissue tissues treating COVID-19 patients Treatment Treatment strategies turn [DOI] 10.1016/j.ejphar.2020.173457 [Article Type] Research article
COVID-19 and Parkinson’s Disease: Shared Inflammatory Pathways Under Oxidative Stress †Article Published on 2020-10-312022-10-28 Journal: Brain Sciences [Category] COVID-19, [키워드] 6OHDA Activation acute respiratory syndrome affected alignment Apoptosis basic Bioinformatics analysis Brain caspase caused cell line Chronic disorder complications contribute coronavirus correlated COVID-19 death ENhance Evidence exacerbate Health human cell identify immortalized Increasing indicated individual Infection inflammatory pathway inhibitors knowledge laboratory data literature review Neuron NFκB nuclear factor kappa B (NFκB) oxidative stress pandemic Parkinson’s disease Parkinson’s disease pathway Patient progression proteome reduced resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 protein selective similarity specific inhibitor Therapeutic approach Toxicity Treatment triggered [DOI] 10.3390/brainsci10110807 PMC 바로가기 [Article Type] Article
The influence of hypoglycemia and hyperglycemia on the adverse outcome of COVID-19 combined with diabetes mellitus A protocol for systematic review and meta-analysis4300 Published on 2020-10-302022-10-30 Journal: Medicine [Category] COVID-19, MERS, SARS, [키워드] adverse outcome Affect Analysis analyzed blood glucose CBM China Chinese chronic inflammation Clinical treatment CNKI Comorbidities conducted Controlled COVID-19 COVID-19 patient database diabete Diabetes Mellitus Epidemic evaluate evaluated Evidence hyperglycemia hypoglycemia independent Infection Inflammatory mediators Infrastructure literature Meta-analysis Mortality Multiple organ damage NOS outcome oxidative stress patients with COVID-19 patients with diabete peer-reviewed Prognosis protocol review Risk of bias Science sensitivity subgroup analysis systematic review systematic review and meta-analysis technology Treatment Trial VIP with COVID-19 [DOI] 10.1097/MD.0000000000022587 PMC 바로가기 [Article Type] 4300
Extracellular Superoxide Dismutase, the Endothelial Basement Membrane, and the WNT Pathway: New Players in Vascular Normalization and Tumor Infiltration by T-CellsArticle Published on 2020-10-302023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] β-catenin diapedesis Extracellular matrix FoxM1 Immunotherapy Laminin oxidative stress ROS [DOI] 10.3389/fimmu.2020.579552 PMC 바로가기
Small Resistance Artery Disease and ACE2 in Hypertension: A New Paradigm in the Context of COVID-19Cardiovascular Medicine Published on 2020-10-302022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] ACE2 alteration angiotensin-converting enzyme 2 Arterial hypertension Artery binding blood flow cardiovascular catalytic domain cause cell entry clinical study Context contribute COVID-19 death Deleterious diagnosed with COVID-19 disease Endothelial dysfunction event events Evidence feature Hyperactivation Inflammation Inflammatory knowledge Local morbidity and mortality New Occurrence organs oxidative oxidative and inflammatory stress oxidative stress PAH paradigm pathology pathophysiology pathway Patient prevalent primary arterial hypertension Protein RAS regulate renin–angiotensin–aldosterone system reported resistance responsible risk SARS-CoV2 small resistance arteries small vessel Stress thrombosis tissue Vascular virus [DOI] 10.3389/fcvm.2020.588692 PMC 바로가기 [Article Type] Cardiovascular Medicine