Comorbid Chronic Diseases and Acute Organ Injuries Are Strongly Correlated with Disease Severity and Mortality among COVID-19 Patients: A Systemic Review and Meta-AnalysisResearch Article Published on 2020-04-192022-10-29 Journal: Research [Category] COVID-19, [키워드] Acute cardiac injury Acute kidney injury addition approach cardiovascular disease chronic chronic condition Chronic kidney disease chronic liver disease Clinical characteristics Clinical course Clinical data Comorbidity complications correlated COVID-19 determine diabete diagnosed with COVID-19 disease severity effective help high mortality rate high risk High-risk patients hypertension identify increased risk Infectious disease management mechanism mitigate Mortality no correlation organ function outbreak outcome parameter pathophysiological pathophysiology Patient patients with COVID-19 raising review risk factor SARS-CoV-2 systemic therapy tissue damage treating COVID-19 Vaccine virus [DOI] 10.34133/2020/2402961 PMC 바로가기 [Article Type] Research Article
Recent progress and challenges in drug development against COVID-19 coronavirus (SARS-CoV-2) – an update on the statusReview Published on 2020-04-192023-05-31 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 조류인플루엔자, [키워드] AlphaCoV, Alpha-coronavirus BetaCoV, Beta-coronavirus CDC, Centers for Disease Control and Prevention coronavirus COVID-19 COVID-19, Coronavirus disease 2019 CT, Computed tomography DeltaCoV, Delta-coronavirus FDA, Food and Drug Administration GammaCoV, Gamma-coronavirus IL-6, Interleukin-6 MERS, Middle East respiratory syndrome Pathogenesis RT-PCR, Real-Time Reverse Transcription Polymerase Chain Reaction SARS-CoV-2 SARS-COV-2, severe acute respiratory syndrome coronavirus-2 SARS, Severe acute respiratory syndrome Severe acute respiratory syndrome therapy Vaccines VLP, virus-like particle WHO, World Health Organization [DOI] 10.1016/j.meegid.2020.104327 PMC 바로가기 [Article Type] Review
Management of Pemphigus in COVID-19 Pandemic Era; a Review ArticleReview Article Published on 2020-04-182022-10-27 Journal: Archives of Academic Emergency Medicine [Category] COVID-19, [키워드] acquisition article auto-immune disease Autoimmune disease Course COVID-19 COVID-19 outbreak COVID-19 pandemic drug Epidemics Evidence immunosuppressive drugs mucous membranes Novel coronavirus outbreak pandemic Patient pemphigus pemphigus vulgaris raised review severe acute respiratory syndrome coronavirus 2 susceptible patient therapy Treatment underlying conditions PMC 바로가기 [Article Type] Review Article
Statins as early therapy to mitigate COVID-19 (SARS-CoV-2)-associated ARDS and cytokine storm syndrome – time is of the essenceMedical Hypothesis Published on 2020-04-182022-10-29 Journal: Journal of Clinical and Translational Research [Category] COVID-19, [키워드] ACE 2 acute respiratory distress syndrome ARDS atorvastatin COVID-19 Cytokine storm Cytokine storm syndrome hyperinflammation microparticles mitigate SARS-CoV-2 statin statins therapy PMC 바로가기 [Article Type] Medical Hypothesis
Extracorporeal membrane oxygenation therapy in the COVID-19 pandemicCommentary Published on 2020-04-172022-10-31 Journal: Future Cardiology [Category] COVID-19, SARS, [키워드] COVID-19 COVID-19 pandemic ECMO Extracorporeal extracorporeal membrane oxygenation therapy membrane Oxygenation therapy [DOI] 10.2217/fca-2020-0040 PMC 바로가기 [Article Type] Commentary
Do checkpoint inhibitors compromise the cancer patients’ immunity and increase the vulnerability to COVID-19 infection?Editorial Published on 2020-04-152022-10-31 Journal: Immunotherapy [Category] COVID-19, [키워드] acute respiratory syndrome administration Cancer cancer patient checkpoints inhibitors claimed coronavirus COVID-19 immune therapy Immunity immunodeficiency Immunosuppression impacted inhibitor malignancy outcome pandemic Patient Prognosis survival the WHO therapy tolerable Toxicity [DOI] 10.2217/imt-2020-0077 PMC 바로가기 [Article Type] Editorial
Controversial treatments: An updated understanding of the coronavirus disease 2019Review Published on 2020-04-102022-10-04 Journal: Journal of medical virology [Category] 치료제, [키워드] absence acute respiratory distress antiviral therapy China Chloroquine Complication complications coronavirus coronavirus disease COVID‐19 Critical Evidence extracorporeal membrane oxygenation glucocorticoid Health help Infection International limitation literature review liver mild patient multiple organ dysfunction organ function outbreak patients Pneumonia reduce reduce mortality Remdesivir ribavirin SARS‐CoV‐2 specific treatment Support syndrome therapy threat Treatment virus [DOI] 10.1002/jmv.25788 PMC 바로가기 [Article Type] Review
Novel coronavirus treatment with ribavirin: Groundwork for an evaluation concerning COVID‐19Review Published on 2020-04-102022-10-30 Journal: Journal of medical virology [Category] COVID-19, SARS, [키워드] antiviral activity antiviral drugs antiviral therapy challenge China clinical trial concerning coronavirus COVID‐19 COVID‐19 described dosage Drug efficacy effective therapy evaluate Evidence in vitro Infection mechanism MERS novel Novel coronavirus outbreak Outbreaks pandemic provide required ribavirin scientific rigor significantly therapeutic therapy Treatment variant viral outbreak [DOI] 10.1002/jmv.25798 PMC 바로가기 [Article Type] Review
COVID-19: immunopathology and its implications for therapy Comments & Opinion Published on 2020-04-092022-10-05 Journal: Nature reviews. Immunology [Category] 바이오마커, 임상, 치료기술, 치료제, [키워드] immunopathology implication therapy [DOI] 10.1038/s41577-020-0308-3 [Article Type] Comments & Opinion
Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection중동 호흡기 증후군 코로나바이러스(MERS-CoV) 스파이크 단백질을 발현하는 재조합 파라인플루엔자 바이러스 5를 사용한 단일 용량, 비강내 면역화로 치명적인 MERS-CoV 감염으로부터 마우스 보호Research Article Published on 2020-04-072022-09-14 Journal: mBio [Category] 진단, 치료제, [키워드] acute respiratory disease administration approved C57BL/6 cause Complete coronavirus CoV COVID-19 develop effective Endemic eosinophil evaluated expressing hDPP4 Human human DPP4 humans immunization immunized immunized mice inactivated indicated intramuscular intranasal lethal infection lung MERS MERS-CoV MERS-CoV infection mice Middle East neutralizing antibody parainfluenza virus provided recombinant respiratory respiratory syndrome coronavirus robust SARS-CoV-2 spike Spike protein T cell response therapy Vaccine vaccine candidate virus clearance [DOI] 10.1128/mBio.00554-20 PMC 바로가기 [Article Type] Research Article