Rapid detection of African swine fever virus using Cas12a-based portable paper diagnosticsArticle Published on 2020-04-072022-10-04 Journal: Cell Discovery [Category] 진단, [키워드] affecting African applied Biological techniques comparable conserved contagious cross-reactivity detect diagnostics Disease surveillance dsDNA economic loss effective Fever Genes lethal disease Molecular biology mutations Pathogens qPCR Rapid responsible robust sensitivity Taking therapy Tolerance Vaccine virus [DOI] 10.1038/s41421-020-0151-5 PMC 바로가기 [Article Type] Article
A Comprehensive Literature Review on the Clinical Presentation, and Management of the Pandemic Coronavirus Disease 2019 (COVID-19)Infectious Disease Published on 2020-04-062022-10-31 Journal: Cureus [Category] COVID-19, [키워드] ACE ACE2 Angiotensin-converting enzyme ARDS Basic science Biochemistry can be used candidate CDC center Chloroquine clinical Clinical course Clinical practice clinical trial Comprehensive Control Coronavirus disease 2019 Corticosteroid COVID-19 COVID19 described diagnostic discharge disease course epidemiological evaluate evaluated Evolution experiment explain Factor Frequency global pandemic H1N1 hindrance hospital ibuprofen Infection information inhibitors limitation literature literature review LOPINAVIR AND RITONAVIR management manuscript media MERS Micronutrient mRNA-1273 vaccine multiple parameter nonsteroidal anti-inflammatory drug NSAIDS outbreak pandemic Phylogeny presentation Prophylaxis Public health interventions remdesivir (GS-5734) review risk factor SARS-CoV-2 self-quarantine severe acute respiratory infection Spread statistical Stratification Symptom the SARS-CoV-2 virus the WHO therapy Treatment viral genome virion Vitamin C [DOI] 10.7759/cureus.7560 PMC 바로가기 [Article Type] Infectious Disease
Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patientsShort Report Published on 2020-04-062022-10-31 Journal: eLife [Category] COVID-19, SARS, [키워드] ACE ACE inhibitor ACE inhibitors ACE-2 ACEi ACEIs Activation acute respiratory distress acute respiratory distress syndrome angiotensin Angiotensin converting enzyme-2 angiotensin receptor antagonists angiotensin receptor blocker angiotensin-converting enzyme-1 angiotensin-converting enzyme-2 ARB ARBs ARDS Arterial hypertension cardiovascular contribute coronavirus Coronavirus disease-19 COVID-19 COVID-19 patient Discontinuing Effect implicated Infection medication pathophysiology pathway Patient plasma Potential Protective RAAS receptor renal renin-angiotensin-aldosterone system respiratory Respiratory failure SARS SARS- CoV-2 SARS-CoV-2 shown syndrome therapeutic therapy Treatment virus [DOI] 10.7554/eLife.57278 PMC 바로가기 [Article Type] Short Report
Antiviral therapy in management of COVID-19: a systematic review on current evidenceReview Article Published on 2020-04-062022-10-27 Journal: Archives of Academic Emergency Medicine [Category] COVID-19, [키워드] addition antiviral agent antiviral therapy can be used clinical trial coronavirus COVID-19 database determine Efficacy Epidemics evaluate Evidence identify independent international organization management MERS-CoV Middle East organization pandemic Patient performed potential treatment option regimen reported researcher respiratory SARS-CoV severe COVID-19 standard treatment systematic review therapy Treatment was performed Web of Science WHO World Health Organization PMC 바로가기 [Article Type] Review Article
Master Regulator Analysis of the SARS-CoV-2/Human InteractomeArticle Published on 2020-04-012022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] ACE2 protein affected apoptotic bioinformatics can be used coronavirus COVID-19 detect develop disease downregulation effort Epidemic gene network analysis host cell Infection interactome knowledge mechanisms mitochondrial molecular feature new virus outbreak performed Proteins reached receptor regulator respiratory tract SARS-CoV-2 therapy virus virus infection [DOI] 10.3390/jcm9040982 PMC 바로가기 [Article Type] Article
Cardiac safety of off-label COVID-19 drug therapy: a review and proposed monitoring protocolReviews Published on 2020-04-012022-10-31 Journal: European heart journal. Acute cardiovascular care [Category] COVID-19, SARS, [키워드] Adverse adverse effect adverse effects American Heart Association Antibiotics antiviral therapy Arrhythmias cardiac cardiac function Cardiomyopathy Care Chloroquine coronavirus 2019 disease COVID-19 drug drugs Effect effective Favipiravir Hydroxychloroquine individual Infection Injury medication monoclonal antibodies Multiple Myocardial off-label offer pandemic patients with COVID-19 point-of-care positive protocol QT interval resource risk therapy Toxicity Treatment [DOI] 10.1177/2048872620922784 PMC 바로가기 [Article Type] Reviews
Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension레닌-안지오텐신계 억제제는 고혈압 환자의 임상 결과를 개선합니다.Letter Published on 2020-03-312022-09-06 Journal: Emerging Microbes & Infections [Category] Communicable Disease, COVID-19, MERS, SARS, [키워드] ACEi ACEIs addition angiotensin Angiotensin II angiotensin II type 1 receptor blockers angiotensin II type1 receptor blockers angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitors antihypertensive drugs ARB ARBs benefit blocker CD3 CD8 T cell Clinical outcome clinical outcomes contribute Coronavirus infection coronavirus infection disease COVID-19 COVID-19 patient COVID-19 patients dysfunction enrolled evaluate the effect Evidence hypertension IL-6 IMPROVE inhibitor Patient patients Peripheral blood RAS RAS inhibitors receiving receptor Receptor Blockers Renin renin-angiotensin system severe disease Support T cell therapy Viral Viral load [DOI] 10.1080/22221751.2020.1746200 PMC 바로가기 [Article Type] Letter
A Systematic Review of Physical Rehabilitation of Facial Palsyarticle Published on 2020-03-312024-09-02 Journal: Frontiers in Neurology [Category] 대상포진, [키워드] central facial palsy exercise rehabilitation systematic review therapy [DOI] 10.3389/fneur.2020.00222 PMC 바로가기 [Article Type] article
A Coronavirus Disease 2019 (COVID-19) Patient with Multifocal Pneumonia Treated with HydroxychloroquineInternal Medicine Published on 2020-03-302022-10-31 Journal: Cureus [Category] COVID-19, [키워드] 2019 novel coronavirus 2019-nCoV acute respiratory syndrome cause China comorbid condition Comorbidity Computed tomography Contact Contagion coronavirus coronavirus disease cough CoV COVID-19 Diagnosis Fever FIVE ground-glass opacity Healthcare system high mortality Hydroxychloroquine Lung Opacity male multifocal myalgia nucleic acid amplification outbreak pandemic Patient Pneumonia positive quarantine risk SARS-CoV-2 sars-cov-2 (severe acute respiratory syndrome coronavirus -2) Self-isolation Shortness of breath subpleural Symptoms tested the patient therapy Thorax Wuhan [DOI] 10.7759/cureus.7473 PMC 바로가기 [Article Type] Internal Medicine
The experience of high-flow nasal cannula in hospitalized patients with 2019 novel coronavirus-infected pneumonia in two hospitals of Chongqing, ChinaResearch Published on 2020-03-302022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] baseline China Chongqing coronavirus Critically ill patient defined HFNC High-flow nasal cannula hospital hospitalized patient indicated Intubated intubation invasive ventilation MOST nasal NIV Noninvasive ventilation Novel coronavirus outbreak Oxygen therapy PaO Patient patients Pneumonia Respiratory failure respiratory rate Result screened Seven significantly Support therapy treated Ventilation [DOI] 10.1186/s13613-020-00653-z PMC 바로가기 [Article Type] Research