Guidelines for the pharmacological treatment of COVID-19. The task-force/consensus guideline of the Brazilian Association of Intensive Care Medicine, the Brazilian Society of Infectious Diseases and the Brazilian Society of Pulmonology and TisiologySpecial Article Published on 2020-01-012022-10-29 Journal: Revista Brasileira de Terapia Intensiva [Category] COVID-19, [키워드] anticoagulation Bacterial Betacoronavirus Brasil Brazil Chloroquine clinical trials conducted Coronavirus infections/drug therapy Corticosteroids COVID-19 Diretrizes effective Effectiveness Evidence GRADE guideline guidelines hospitalized patients Infecções por coronavirus/tratamento farmacológico Infectious disease Influenza information Interpretation Intervention Medicine methodologist oseltamivir Patient pharmacological pharmacological treatment professional provided Pulmonology Rapid recommendation Result Safe SARS-CoV-2 Society systematic reviews Therapies therapy Tocilizumab treated Treatment use of hydroxychloroquine was performed [DOI] 10.5935/0103-507X.20200039 PMC 바로가기 [Article Type] Special Article
Approaches for the Treatment of SARS-CoV-2 Infection: A Pharmacologic View and Literature ReviewReview Article Published on 2020-01-012022-10-30 Journal: Iranian Journal of Pharmaceutical Research : IJPR [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome (ARDS) approach ARDS caused China clinical manifestations clinical trial coronavirus coronavirus 2 Coronavirus disease 2019 COVID-19 COVID-19 disease disease drugs targeting effective effective drug effort elements host cell identify knowledge literature medication Mild moderate new virus offered outcomes pandemic Pharmacologic potential therapy public health Quickly respiratory review SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus severity Spread Stage suggested syndrome the disease therapy Treatment View virus [DOI] 10.22037/ijpr.2020.113821.14506 PMC 바로가기 [Article Type] Review Article
Tracing the decision-making process for myelofibrosis: diagnosis, stratification, and management of ruxolitinib therapy in real-word practiceOriginal Article Published on 2019-12-122024-09-02 Journal: Annals of Hematology [Category] 대상포진, [키워드] myelofibrosis Real-life practice ruxolitinib survey therapy [DOI] 10.1007/s00277-019-03847-z PMC 바로가기 [Article Type] Original Article
In vivo models for studying Hepatitis E virus infection; Updates and applicationsReview Published on 2019-12-012023-06-10 Journal: Virus research [Category] E형 간염, [키워드] animal model Cross-species infection HEV Pregnancy therapy Virus-host interaction [DOI] 10.1016/j.virusres.2019.197765 [Article Type] Review
History of Inflammatory Bowel DiseasesReview Published on 2019-11-142024-09-02 Journal: Journal of Clinical Medicine [Category] 대상포진, [키워드] bowel Inflammation Inflammatory bowel disease interactome therapy ulcerative colitis [DOI] 10.3390/jcm8111970 PMC 바로가기 [Article Type] Review
Non-invasive bioluminescence imaging of HCoV-OC43 infection and therapy in the central nervous system of live miceArticle Published on 2019-11-062023-06-15 Journal: Antiviral Research [Category] MERS, [키워드] bioluminescence imaging Chloroquine coronavirus mouse therapy [DOI] 10.1016/j.antiviral.2019.104646 PMC 바로가기 [Article Type] Article
A randomized open label trial of tenofovir monotherapy versus tenofovir plus telbivudine in spontaneous reactivation of hepatitis BRandomized Controlled Trial Published on 2019-09-012023-06-19 Journal: Saudi journal of gastroenterology : official journ [Category] B형 간염, [키워드] Hepatitis Reactivation tenefovir and combination therapies therapy [DOI] 10.4103/sjg.SJG_537_18 PMC 바로가기 [Article Type] Randomized Controlled Trial
Attenuating the emergence of anti-fungal drug resistance by harnessing synthetic lethal interactions in a model organism모델 유기체에서 합성 치명적인 상호 작용을 활용하여 항진균제 내성의 출현을 완화Research Article Published on 2019-08-192022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allele alleles antifungal drug resistance antifungal therapy antimicrobial resistance approach Bacteria best Candida Care caused Cell clinically combination therapies Community community acquired death Deletion drug drug resistance drug-resistant drugs effective Evolution experiments Express expressing FIVE fluconazole fungal Fungal infection fungal infections fungi Gain gain-of-function Genetic genetic component genetic screens genus growth hospitals Host identify Immunosuppressed inactivation incidence Infection infections inhibit inhibited Interaction investigated isolate knowledge life life-threatening mediator mediators Medical care Mortality MRSA mucosal mutant Mutation organism pathogen Pathogens patient population performed phenotype powerful tool Prevent proof proof of concept Protein provide resistance mechanisms responsible Saccharomyces cerevisiae significantly target target proteins Testing therapy thrush Treatment yeast [DOI] 10.1371/journal.pgen.1008259 PMC 바로가기 [Article Type] Research Article
Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies새로운 효모 단백병증 모델 및 유전자 변형 파리에서 PBP1/ATXN2 기능의 손실에 의해 칼슘 반응성 트랜스활성제(CREST) 독성이 구출됩니다Research Article Published on 2019-08-072022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] addition Affect aggregate aggregation ALS Amyotrophic lateral sclerosis ATXN2 calcium caused chaperone CREST cytoplasmic degenerative Deletion disease Disease model Diseases downregulation Drosophila effective enhancer expressed facilitate foci form ganglion cell ganglion cells Genes inhibit Lateral Sclerosis Like Localization mammalian cells mechanism modify Mutation neurodegenerative neurons nuclear ortholog overexpressing overexpression phenotype Propagation Protein Proteins reduce reduced regulated required rescued risk factor shown Spectrum SS18L1 targets therapeutic target therapy Thioflavin toxic Toxicity transgenic yeast yeast form yeast forms [DOI] 10.1371/journal.pgen.1008308 PMC 바로가기 [Article Type] Research Article
microRNAs: Key players in virus-associated hepatocellular carcinomaReview Published on 2019-08-012023-06-16 Journal: Journal of cellular physiology [Category] B형 간염, [키워드] Exosome HBV HCV Hepatocellular carcinoma microRNA therapy [DOI] 10.1002/jcp.27956 [Article Type] Review