Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patientsResearch Article Published on 2020-09-082022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] Care Chest CT classical clinical collected COVID-19 COVID-19 case COVID-19 patient detection Diagnosis digital PCR disease disease severity evaluated False negative female Hospital admission Host identify individuals with COVID-19 interstitial management median median age Molecular diagnosis nasopharyngeal sample Nasopharyngeal swab negative test pandemic Patient patients performed positive quantification raise RdRP Real-time PCR reduce respiratory sample reverse transcription PCR RNAseP Sample SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 genome Serological assay severe COVID-19 manifestations Spread tested [DOI] 10.1371/journal.pone.0236311 PMC 바로가기 [Article Type] Research Article
Simple, Low-Cost and Long-Lasting Film for Virus Inactivation Using Avian Coronavirus Model as ChallengeArticle Published on 2020-09-042022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Antiviral caused challenge Contact contaminated surface coronavirus COVID-19 infection detergent Direct dose Efficacy expected film flammable inactivated inactivation infective maintain Model morphologically polystyrene Population populations quantification RNA virus RT-qPCR sanitization SARS-CoV-2 shown simple Spread spread of COVID-19 virucidal virucide virus virus infectivity was determined was used [DOI] 10.3390/ijerph17186456 PMC 바로가기 [Article Type] Article
Curative anticoagulation prevents endothelial lesion in COVID-19 patientsObservational Study Published on 2020-09-012022-10-04 Journal: Journal of thrombosis and haemostasis : JTH [Category] 임상, [키워드] Adding Admission Analysis analyzed angiotensin receptor blocker Anticoagulant anticoagulation biological profile cardiovascular complication characteristic circulating circulating endothelial cells coagulation disorders Coagulopathy Computed tomography cough COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19 patient COVID-19 patients criteria CT scan curative D-dimer D-dimers Disseminated intravascular coagulation endothelial Endothelial cell Endothelial dysfunction Fever Gender Hemostasis Hospitalization inhibitor Patient patients treated Pneumonia positive Prevent quantification SARS-CoV-2 significantly increased significantly more tested [DOI] 10.1111/jth.14968 PMC 바로가기 [Article Type] Observational Study
Recent Progress in Plasmonic Biosensing Schemes for Virus DetectionReview Published on 2020-08-222022-10-29 Journal: Sensors (Basel, Switzerland) [Category] COVID-19, MERS, [키워드] approaches Biomarker Colorimetric Combination complement coronavirus 2 coronavirus disease COVID-19 dengue virus detection Diagnostic method diagnostic methods Diseases Ebola virus effective Electrochemiluminescence ELISA enzyme-linked immunosorbent assay Hepatitis Infectious disease Influenza virus limitation LSPR Luminescence nanomaterials PCR Perspective plasmonics platform polymerase chain Progress public health quantification recent receptor respiratory SARS-CoV-2 scattering SERS SPR stability virus virus detection Zika virus [DOI] 10.3390/s20174745 PMC 바로가기 [Article Type] Review
3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomographyResearch Article Published on 2020-08-202022-10-31 Journal: eLife [Category] COVID-19, MERS, [키워드] 3d histology approach Autopsy characteristic COVID-19 cross DAD Diffuse alveolar damage distribution histology Histopathology Human hyaline membrane formation individual cells infiltrating interior lung tissue lymphocyte parenchymal pathophysiology Patient phase contrast quantification reconstructed tissue tissue remodeling tomography X-ray [DOI] 10.7554/eLife.60408 PMC 바로가기 [Article Type] Research Article
The “pandemic” increase in lung ultrasound use in response to Covid-19: can we complement computed tomography findings? A narrative reviewReview Published on 2020-08-172022-10-29 Journal: The Ultrasound Journal [Category] COVID-19, [키워드] acute respiratory syndrome affected caused chest HRCT complement Computed tomography coronavirus COVID-19 critical care patient Diagnosis disease emergency condition Evidence feature global pandemic Healthcare system High-resolution HRCT increase in Infectious disease intensive care less lung lung disorders management Multidetector computed tomography Patient Pneumonia point-of-care pulmonary conditions pulmonary involvement quantification Respiratory distress syndrome, adult SARS-CoV-2 Severe acute respiratory syndrome severity spread to Thorax Ultrasonography while [DOI] 10.1186/s13089-020-00185-4 PMC 바로가기 [Article Type] Review
RCOVID19: Recurrence-based SARS-CoV-2 features using chaos game representationBiochemistry, Genetics and Molecular Biology Published on 2020-08-072022-10-31 Journal: Sensors (Basel, Switzerland) [Category] COVID-19, [키워드] acute respiratory syndrome Analysis Chaos game representation China Coordinate series coronavirus COVID-19 pandemic dataset effective feature genomic sequence identify instance Nonlinear analysis provided quantification Recurrence quantification analysis reported responsible SARS-CoV-2 spread to whole genome sequence [DOI] 10.1016/j.dib.2020.106144 PMC 바로가기 [Article Type] Biochemistry, Genetics and Molecular Biology
Assay validation and determination of in vitro binding of mefloquine to plasma proteins from clinically normal and FIP-affected catsResearch Article Published on 2020-08-052022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, [키워드] Accuracy antimalarial Antiviral average binding calicivirus clinical trial clinically coefficient Concentration coronavirus demonstrated detect dialysis dosing regimens expressed in vitro in vivo infections inhibit investigated limit plasma plasma concentration plasma protein Plasma Protein Binding Population Precision proportion Proteins quantification reported Standard deviation Variation [DOI] 10.1371/journal.pone.0236754 PMC 바로가기 [Article Type] Research Article
Estimation of COVID-19 spread curves integrating global data and borrowing informationResearch Article Published on 2020-07-292022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] adopted approved Bayesian country COVID-19 drug estimation food Health Hierarchical identify infected cases Infection information joint novel coronavirus disease outperform pandemic Predictive Prevent provide quantification risk factor severe disease Spread the disease trajectory treat virus [DOI] 10.1371/journal.pone.0236860 PMC 바로가기 [Article Type] Research Article
Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman PrimatesOriginal Article Published on 2020-07-282022-11-01 Journal: The New England Journal of Medicine [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Analysis antibody Antigen BAL BAL fluid CD4 T-cell CD8 T-cell responses changes in coronavirus coronavirus disease detectable Dilution dose eight evaluate geometric mean titer groups histopathological Inflammation inhibitory lower airway lower airways lung mRNA-1273 mRNA-1273 vaccine nasal swab Neutralizing activity pathologic performed polymerase chain Prevent primate quantification Replication response Result robust SARS-CoV-2 serum Seven specimen specimens Spike protein T-cell T-cell Response Th2 type 1 helper undetectable Vaccine vaccine group viral genome viral replication were assessed [DOI] 10.1056/NEJMoa2024671 PMC 바로가기 [Article Type] Original Article